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产品数：86101
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T6124MubritinibMubritinib,TAK-165,
Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
价 格：￥电议型 号：T6124产 地：美洲
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T6283WortmanninWortmannin,KY-12420,SL-2052
Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM, with little selectivity within the PI3K family. Also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM.
价 格：￥电议型 号：T6283产 地：美洲
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T6509GaleteroneGaleterone,VN-124-1,TOK-001
Galeterone is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an androgen receptor antagonist, 2) as a CYP17 l
价 格：￥电议型 号：T6509产 地：美洲
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T8661AS601245.2TFA (345987-15-7 free base)；化合物AS601245.2TFAAS601245.2TFA；AS601245.2TFA
AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively).
价 格：￥电议型 号：T8661产 地：中国大陆
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T8587EcDsbB-IN-12；化合物EcDsbB-IN-124,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one；4,5-dichloro-2-[(
EcDsbB-IN-12 (4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one) targets disulfide bond forming enzyme,and is a novel potent specific inhibitor of EcDsbB.
价 格：￥电议型 号：T8587产 地：中国大陆
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T83962C 101248；化合物 C 101248C 101248
C 101248 is a selective and potent inhibitor targeting both mouse and human tandem pore domain halothane-inhibited K+ channel 1 (THIK-1, IC50= 50 nM), without affecting the K2P family members (TREK-1, TWIK-2) and Kv2.1. This compound effectively blocks tonic and ATP-evoked THIK-1 K+ currents as observed in whole-cell patch-clamp recordings of mouse hippocampal microglia. Additionally, C 101248 mitigates neuroinflammation by inhibiting the NLRP3-dependent release of IL-1β in isolated microglia.
价 格：￥电议型 号：T83962产 地：中国大陆
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T83124Amylocaine；化合物 AmylocaineAmylocaine
Amylocaine, an ester-type local anesthetic, induces reversible insensitivity in the vicinity of its application and is primarily utilized for spinal anesthesia [1].
价 格：￥电议型 号：T83124产 地：中国大陆
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T82858Bleselumab；化合物 BleselumabASKP 1240|||Anti-Human CD40 Recombinant Antibody；ASKP 1240|||Anti-Human CD4
Bleselumab (ASKP 1240), a human anti-CD40 monoclonal antibody (mAb), exhibits high-affinity binding to CD40 (Kd: 0.24 nM) and hinders immune responses by impeding the CD40-CD40L interaction, thereby preventing organ transplant rejection [1].
价 格：￥电议型 号：T82858产 地：中国大陆
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T8230PNU112455A hydrochloride；化合物PNU 112455APNU 112455A；PNU 112455A
PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
价 格：￥电议型 号：T8230产 地：中国大陆
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T82124ICMT-IN-20；化合物 ICMT-IN-20ICMT-IN-20
ICMT-IN-20 (compound 54) serves as an ICMT inhibitor with an IC50 value of 0.682 μM [1].
价 格：￥电议型 号：T82124产 地：中国大陆
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T81249Ru3；化合物 Ru3Ru3
Ru3 is a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor that prompts apoptosis in MCF-7 cells through various mechanisms, including DNA damage induction, inhibition of DNA repair, alteration of cell cycle distribution, reduction of mitochondrial membrane potential, and elevation of intracellular reactive oxygen species (ROS) levels [1].
价 格：￥电议型 号：T81249产 地：中国大陆
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T81248Rubriflorin B；化合物 Rubriflorin BRubriflorin B
Rubriflorin B, a lignan derived from Schisandra rubriflora [1], can be isolated for various applications.
价 格：￥电议型 号：T81248产 地：中国大陆
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T81247Runimotamab；化合物 RunimotamabRunimotamab
Runimotamab, an IgG1-κ humanized chimeric antibody, targets CD3E and HER2 [1].
价 格：￥电议型 号：T81247产 地：中国大陆
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T81246RXFP1 receptor agonist-1；化合物 RXFP1 receptor agonist-1RXFP1 receptor agonist-1
RXFP1 receptor agonist-1 (Example 2), an agonist of the RXFP1 receptor, suppresses cAMP production in HEK293 cells that constitutively express the human RXFP1, exhibiting an EC50 of 300 nM [1].
价 格：￥电议型 号：T81246产 地：中国大陆
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T81245RXFP1 receptor agonist-2；化合物 RXFP1 receptor agonist-2RXFP1 receptor agonist-2
RXFP1 Receptor Agonist-2 (Example 124), an EC50 value of 1 nM [1].
价 格：￥电议型 号：T81245产 地：中国大陆
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T81244RXFP1 receptor agonist-3；化合物 RXFP1 receptor agonist-3RXFP1 receptor agonist-3
RXFP1 receptor agonist-3 (Example 223) is an agonist of the RXFP1 receptor that inhibits cyclic AMP (cAMP) production in HEK293 cells stably expressing human RXFP1, boasting an EC50 of 2 nM [1].
价 格：￥电议型 号：T81244产 地：中国大陆
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T81243RXFP1 receptor agonist-4；化合物 RXFP1 receptor agonist-4RXFP1 receptor agonist-4
RXFP1 receptor agonist-4 (Example 268) is an agonist for the RXFP1 receptor, demonstrated to suppress cAMP production in HEK293 cells that stably express the human RXFP1 receptor, exhibiting an effective concentration (EC50) of 4.9 nM [1].
价 格：￥电议型 号：T81243产 地：中国大陆
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T81242RXFP1 receptor agonist-5；化合物 RXFP1 receptor agonist-5RXFP1 receptor agonist-5
RXFP1 receptor agonist-5 (Example 98) is an agonist that targets the RXFP1 receptor and demonstrates its bioactivity by inhibiting cAMP production in HEK293 cells with stable human RXFP1 expression, exhibiting an EC50 of 1.3 nM [1].
价 格：￥电议型 号：T81242产 地：中国大陆
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T81241RXFP1 receptor agonist-6；化合物 RXFP1 receptor agonist-6RXFP1 receptor agonist-6
RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably express the human RXFP1, exhibiting an EC50 of 12 nM [1].
价 格：￥电议型 号：T81241产 地：中国大陆
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T81240RXFP1 receptor agonist-7；化合物 RXFP1 receptor agonist-7RXFP1 receptor agonist-7
RXFP1 receptor agonist-7 (Example 2) serves as an RXFP1 receptor agonist, effectively inhibiting cAMP production in HEK293 cells that stably express the human RXFP1, achieving an EC50 of 4.2 nM [1].
价 格：￥电议型 号：T81240产 地：中国大陆
