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T61248HDAC-IN-32;化合物 HDAC-IN-32HDAC-IN-32
HDAC-IN-32 is a highly effective HDAC inhibitor presenting IC50 values of 5.2, 11, and 28 nM for HDAC1, HDAC2, and HDAC6, respectively. This compound demonstrates notable anti-proliferative properties against tumor cells, as well as significant in vivo antitumor efficacy, which can elicit antitumor immunity [1].
价 格:¥电议型 号:T61248产 地:中国大陆
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T61247TRK-IN-16;化合物 TRK-IN-16TRK-IN-16
TRK-IN-16 (WO2012034091A1, compound X-21) is a highly effective TRK inhibitor, targeting protein kinases that are integral to regulating cell growth, differentiation, and various cellular signal transduction processes. This compound shows great potential for research in TRK-related diseases [1].
价 格:¥电议型 号:T61247产 地:中国大陆
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T61246TRK-IN-15;化合物 TRK-IN-15TRK-IN-15
TRK-IN-15 (WO2012034091A1, compound X-55) is a highly effective inhibitor of TRK, a protein kinase with crucial involvement in the regulation of cellular growth, differentiation, and signal transduction. Offering significant potential for studying TRK-related diseases, TRK-IN-15 holds promise for advancing research in this field [1].
价 格:¥电议型 号:T61246产 地:中国大陆
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T61245Antiparasitic agent-7;化合物 Antiparasitic agent-7Antiparasitic agent-7
Antiparasitic agent-7 (compound 5d) displays specific antiparasitic activity against Leishmania infantum (L. infantum), exhibiting an IC50 value of 2.85 μM. Additionally, Antiparasitic agent-7 demonstrates cytotoxicity against HepG2 cells with a CC50 value of 10.61 μM [1].
价 格:¥电议型 号:T61245产 地:中国大陆
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T61244AhR agonist 2;化合物 AhR agonist 2AhR agonist 2
AhR agonist 2 (Compound 12a) is a highly potent agonist of the aryl hydrocarbon receptor (AhR), exhibiting an EC50 value of 0.03 nM. This compound rapidly induces nuclear enrichment of AhR and initiates transcription of downstream genes, thereby promoting skin barrier repair. AhR agonist 2 shows promising potential for psoriasis research [1].
价 格:¥电议型 号:T61244产 地:中国大陆
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T61243MAT2A-IN-5;化合物 MAT2A-IN-5MAT2A-IN-5
MAT2A-IN-5, a potent inhibitor of MAT2A, effectively targets the abnormally elevated expression of MAT2A found in various tumor types such as gastric, colon, liver, and pancreatic cancers. By reducing the proliferative activity of MTAP-deficient cancer cells, MAT2A-IN-5 exhibits potential in cancer research applications [1].
价 格:¥电议型 号:T61243产 地:中国大陆
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T61242Tubulin inhibitor 12;化合物 Tubulin inhibitor 12Tubulin inhibitor 12
Tubulin inhibitor 12 (Hit 9) is a recently developed compound with potent inhibitory effects on tubulin (IC50 = 25.3 μM). This compound exhibits noteworthy anti-tumor and anti-proliferative activities, making it a promising candidate for the treatment of cancer [1].
价 格:¥电议型 号:T61242产 地:中国大陆
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T6124Mubritinib;木利替尼TAK-165;木利替尼|||TAK-165
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
价 格:¥电议型 号:T6124产 地:中国大陆
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T61124α-Glucosidase-IN-9;化合物 α-Glucosidase-IN-9α-Glucosidase-IN-9
α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].
价 格:¥电议型 号:T61124产 地:中国大陆
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T61122ZINC12409120;化合物ZINC12409120R-4584;R-4584
ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23:α-Klotho interaction.
价 格:¥电议型 号:T61122产 地:中国大陆
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T60921LPF-07038124 HCl(2415085-44-6 Free base);化合物 PF-07038124 HCl(2415085-44-6 Free base)PF-07038124 HCl(2
产品可用于生物细胞实验
价 格:¥电议型 号:T60921L产 地:中国大陆
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T60921PF-07038124;化合物 PF-07038124PF-07038124
PF-07038124 is an inhibitor of PDE4. The IC50 value of PF-07038124 for PDE4B2 is 0.5 nM. PF-07038124 shows inhibitory activities against IFNγ, IL4, and IL-13 with IC50 values of 1.06, 4.1, and 125 nM, respectively [1].
价 格:¥电议型 号:T60921产 地:中国大陆
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T60165VB124;化合物VB124VB124
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for lactate import and export, respectively, in MDA-MB-231 cells. Its high selectivity for MCT4 over MCT1 positions VB124 as a promising agent for researching cardiac hypertrophy, heart failure, and metabolic disorders [1].
价 格:¥电议型 号:T60165产 地:中国大陆
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T5124SRT 1720 dihydrochloride[925434-55-5(free base)];化合物SRT 1720 dihydrochloride[SRT 1720 dihydrochlorid
SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).
价 格:¥电议型 号:T5124产 地:中国大陆
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T4S124714-Hydroxy sprengerinin C14-羟基麦冬皂苷 C14-羟基麦冬皂苷C|||14-羟基麦冬皂苷 C
14-Hydroxy sprengerinin C is a natural product from Ophiopogon japonicus.
价 格:¥电议型 号:T4S1247产 地:中国大陆
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T4490PF-01247324;化合物PF01247324PF-01247324
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
价 格:¥电议型 号:T4490产 地:中国大陆
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T41249Tenofovir alafenamide fumarate;替诺福韦艾拉酚胺富马酸盐GS-7340 fumarate;GS-7340 fumarate
Tenofovir alafenamide fumarate (GS-7340 fumarate) is an orally available Tenofovir precursor compound Tenofovir alafenamide fumarate has anti-HIV activity and can be used to prevent HIV infection.
价 格:¥电议型 号:T41249产 地:中国大陆
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T41248Thiocolchicine;硫代秋水仙碱Thiocolchicine
Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 ?M and a Ki of 0.7 ?M. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
价 格:¥电议型 号:T41248产 地:中国大陆
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T41247Thioperamide maleate;硫丙咪胺马来酸MR-12842 maleate;MR-12842 maleate|||硫丙咪胺马来酸
Thioperamide maleate (MR-12842 maleate) is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31 nM).
价 格:¥电议型 号:T41247产 地:中国大陆
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T41246Thromboxane B2;化合物 Thromboxane B2Thromboxane B2
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces platelet aggregation and arterial contraction.
价 格:¥电议型 号:T41246产 地:中国大陆