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T41245Trimethylamine N-oxide;三甲胺N-氧化物Trimethylamine N-oxide
Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging effects of urea.Trimethylamine N-oxide induces inflammation through activation of ROS/NLRP3 inflammasomes, which can induce fibroblast differentiation and cardiac fibrosis.
价 格:¥电议型 号:T41245产 地:中国大陆
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T41244Triticonazole;灭菌唑Triticonazole
Triticonazole is a triazole pesticide and fungicide. Triticonazole shows endocrine disrupting activities.
价 格:¥电议型 号:T41244产 地:中国大陆
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T41243Tumulosic acid;化合物 Tumulosic acidTumulosic acid
Tumulosic acid is a natural product for research related to life sciences. The catalog number is T41243 and the CAS number is 508-24-7.
价 格:¥电议型 号:T41243产 地:中国大陆
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T41242Uric acid sodium尿酸钠尿酸钠
Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, has an inhibitory effect on lipid peroxidation and is associated with the pathogenesis of gout joint disease and the formation of calcium oxalate stones.
价 格:¥电议型 号:T41242产 地:中国大陆
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T41240Verrucarin A;化合物 Verrucarin AVerrucarin A
Verrucarin A (Muconomycin A) is a Type D macrocyclic mycotoxin. Verrucarin A (VA), a protein synthesis inhibitor, derived from the pathogen fungus Myrothecium verrucaria, inhibits growth of leukemia cell lines and activates caspases and apoptosis and inflammatory signaling in macrophages. Verrucarin A effectively increased the phosphorylation of p38 MAPK and diminished the phosphorylation of ERK/Akt. Verrucarin A caused cell cycle deregulation through the induction of p21 and p53 [1] [2].
价 格:¥电议型 号:T41240产 地:中国大陆
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T4124IKarisoside A;大花淫羊藿苷 AIcarisoside-|||Baohuoside II;Icarisoside-|||Baohuoside II
IKarisoside A(Baohuoside II) is a flavonol glycoside from the Berberidaceae plant Epimedium, with anti-inflammatory activity.
价 格:¥电议型 号:T4124产 地:中国大陆
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T41124Kizuta saponin K11;Kizuta saponin K11Kizuta saponin K11
Kizuta saponin K11 is a saponin derived from Kalopanax pictum var. maximowiczii leaves, which is a widely used Korean medicinal plant.
价 格:¥电议型 号:T41124产 地:中国大陆
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T4059Selamectin;塞拉菌素UK-124114;UK-124114|||司拉克丁|||塞拉菌素
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth inhibition.
价 格:¥电议型 号:T4059产 地:中国大陆
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T40124Antifungal agent 20;Antifungal agent 20Antifungal agent 20
Antifungal agent 20 demonstrates significant antifungal efficacy against a range of fungal pathogens including Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum.
价 格:¥电议型 号:T40124产 地:中国大陆
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T39124BAY 1217224;BAY 1217224BAY 1217224
BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.
价 格:¥电议型 号:T39124产 地:中国大陆
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T38147(S)-AM1241;(S)-AM1241(S)-AM1241;(S)-AM1241
(S)-AM1241 binds to cannabinoid (CB) receptors and is selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively, in a membrane assay using human receptors). (S)-1241 acts as an agonist at human, rat, and mouse CB2 receptors but shows greater activity at human CB2 (EC50 = 131 nM) than at rat and mouse CB2 receptors (EC50 = 785 and 2,000 nM, respectively). Similar to the racemate AM1241 , (S)-AM1241 produces antinociception to thermal, but not mechanical, pain in rats. Th
价 格:¥电议型 号:T38147产 地:中国大陆
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T37449SR 12460;SR 12460SR 12460
SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits TNF-α-induced NF-κB activation in a reporter assay when used at concentrations ranging from 25 to 150 μM. It reduces LPS-induced production of IL-6 in RAW 264.7 cells. SR 12460 (30 mg/kg) improves grip strength in themdxmouse model of Duchenne muscular dystrophy.
价 格:¥电议型 号:T37449产 地:中国大陆
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T371241,3-Dipalmitoleoyl-rac-glycerol;1,3-Dipalmitoleoyl-rac-glycerol1,3-Dipalmitoleoyl-rac-glycerol
1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. It selectively inhibits α-glucosidase from S. cerevisiae over rat enzyme (IC50s = 4.45 and 9,326.5 μM, respectively). 1,3-Dipalmitoleoyl-rac-glycerol has been used in the formation of lipid bilayers to study the effects of membrane composition and the ionophore valinomycin on membrane potential.
价 格:¥电议型 号:T37124产 地:中国大陆
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T36884BM-1244;BM-1244BM-1244
BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC50 of 5 nM[1].
价 格:¥电议型 号:T36884产 地:中国大陆
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T361243β-hydroxy-5-Cholestenoic Acid;3β-hydroxy-5-Cholestenoic Acid3β-hydroxy-5-Cholestenoic Acid
3β-hydroxy-5-Cholestenoic Acid is one of the metabolites of cholesterol found in high concentrations (40-80 ng/ml) in human circulation.
价 格:¥电议型 号:T36124产 地:中国大陆
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T35253YM 11124;化合物 T35253YM-11124|||YM11124;YM-11124|||YM11124
YM 11124 is a biochemical.
价 格:¥电议型 号:T35253产 地:中国大陆
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T35124Wd 67-2;化合物 T35124Wd67-2|||Wd-67-2;Wd67-2|||Wd-67-2
Wd 67-2 is a biochemical.
价 格:¥电议型 号:T35124产 地:中国大陆
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T34798Telapristone;化合物 T34798metabolite of telapristone acetate (CDB-4124);metabolite of telapristone acet
Telapristone, is the active metabolite of telapristone acetate (also known as CDB-4124). Telapristone is a selective progesterone receptor modulator (SPRM) being studied for the treatment of certain progesterone-sensitive conditions.
价 格:¥电议型 号:T34798产 地:中国大陆
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T34124Pranolium;化合物 T34124UM-272|||SC-27761|||UM 272|||SC 27761|||SC27761;UM-272|||SC-27761|||UM 272|||SC
Pranolium is a quaternary dimethyl derivative of Propranolol, a well-known powerful betareceptor-blocking agent.
价 格:¥电议型 号:T34124产 地:中国大陆
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T33907PEG-9 Laurate;化合物 T33907NSC 1249|||Lipal 4L|||NSC-1249|||Lipal 4ML|||NGML;NSC 1249|||Lipal 4L|||NSC-
PEG-9 Laurate is a bioactive chemical.
价 格:¥电议型 号:T33907产 地:中国大陆