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T71832CTX-0124143;CiproquazoneCTX-0124143
CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.
价 格:¥电议型 号:T71832产 地:中国大陆
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T71747IKK?-IN-124;化合物 IKK?-IN-124IKK?-IN-124
IKK?-IN-124 is an allosteric inhibitor of IκBα phosphorylation and NF-κB transcriptional activity through selective capture of the inactive conformation and hence blockade of IKKβ S177/S181 phosphorylation.
价 格:¥电议型 号:T71747产 地:中国大陆
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T71249NCX-278;化合物 NCX-278NCX-278
NCX-278 is a ROCK inhibitor and NO-donating anti-glaucoma agent.
价 格:¥电议型 号:T71249产 地:中国大陆
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T71248AM0216;化合物 AM0216AM0216
AM0216 is a novel highly potent inhibitor of NF-κB inducing Kinase (NIK).
价 格:¥电议型 号:T71248产 地:中国大陆
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T71247PU-H71 hydrate;化合物 PU-H71 hydratePU-H71 hydrate
PU-H71 hydrate is a potent inhibitor of heat shock protein 90 (Hsp90).
价 格:¥电议型 号:T71247产 地:中国大陆
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T71246DD04107;化合物 DD04107DD04107
DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1.
价 格:¥电议型 号:T71246产 地:中国大陆
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T71245ARRY-502;化合物 ARRY-502ARRY-502
ARRY-502 is a CRTH2 antagonist. Regulation of cytokine activity is important in molecularly targeted therapies for asthma.
价 格:¥电议型 号:T71245产 地:中国大陆
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T71243ASP3662;化合物 ASP3662ASP3662
ASP3662, also known as SPI-62, is a potent, selective and CNS-penetrable inhibitor of 11β-HSD1. The effects of ASP3662 suggest that selective inhibition of 11β-HSD1 may be an attractive approach for the treatment of neuropathic and dysfunctional pain, as observed in fibromyalgia. ASP3662 inhibited human, mouse and rat 11β-HSD1 but not human 11β-HSD2, in vitro. ASP3662 inhibited in vitro conversion of glucocorticoid from its inactive to active form in extracts of rat brain and spinal cord.
价 格:¥电议型 号:T71243产 地:中国大陆
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T71242AZD-1897;化合物 AZD-1897AZD-1897
AZD-1897 is an ATP-competitive pan-PIM inhibitor. When combined with the Akt inhibitor AZD5363, AML cells from putative leukaemia stem cells incur a reduction in levels of the anti-apoptotic protein MCL1. The combination of PIM and Akt inhibition holds promise for the treatment of AML.
价 格:¥电议型 号:T71242产 地:中国大陆
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T71241Carbovir;化合物 CarbovirCarbovir
Carbovir, also known as (-)-Carbovir, is a nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) caused mitochondrial toxicity in human hepatoma carcinoma cell.
价 格:¥电议型 号:T71241产 地:中国大陆
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T71240AS 703026;化合物 AS 703026AS 703026
AS 703026 has been shown to inhibit LPS-induced TNFα production in macrophages/monocytes as well as protect from LPS-induced endotoxin shock. AS 703026 may be useful as an anti-inflammatory therapy for COPD patients.
价 格:¥电议型 号:T71240产 地:中国大陆
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T7124Dinotefuran呋虫胺MTI-446|||呋虫胺
Dinotefuran (MTI-446) is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves disruption of the insect´s nervous system by inhibiting nicotinic acetylcholine receptors.
价 格:¥电议型 号:T7124产 地:中国大陆
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T71124NNC 112;化合物 NNC 112NNC 112
NNC 112 is a selective dopamine D1 receptor antagonists.
价 格:¥电议型 号:T71124产 地:中国大陆
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T70452PD 151242;化合物 PD 151242PD 151242
PD 151242 is an endothelin receptor antagonist.
价 格:¥电议型 号:T70452产 地:中国大陆
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T70124Tomivosertib HCl;化合物 Tomivosertib HClTomivosertib HCl
Tomivosertib, also known as eFT508 is a MNK1/2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1/2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling.
价 格:¥电议型 号:T70124产 地:中国大陆
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T70055CO-101244 Free Base;化合物 CO-101244 Free BaseCO-101244 Free Base
CO-101244 Free Base is an NMDA receptor NR2B subunit blocker.
价 格:¥电议型 号:T70055产 地:中国大陆
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T6963Reboxetine mesylate;甲磺酸瑞波西汀FCE20124 mesylate|||Edronax|||PNU155950E mesylate|||PNU 155950E;瑞波西汀甲磺酸盐|
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
价 格:¥电议型 号:T6963产 地:中国大陆
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T69124Alprenolol glucuronide;化合物 Alprenolol glucuronideAlprenolol glucuronide
Alprenolol glucuronide is the glucoronide salt of Aprenolol --- a beta blocker.
价 格:¥电议型 号:T69124产 地:中国大陆
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T68876BXL0124;化合物 BXL0124BXL0124
BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.
价 格:¥电议型 号:T68876产 地:中国大陆