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T68173ZD-2138;化合物Zd-2138Ici-D2138;Ici-D2138
ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolated airways in guinea pigs.ZD-2138 can be used for the treatment of asthma disease.
价 格:¥电议型 号:T68173产 地:中国大陆
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T68138Saterinone;沙泰尼酮Saterinone
Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic heart failure. Saterinone inhibited crude cAMP phosphodiesterase (PDE) activity in guinea pig right ventricular homogenates The ic50 value is 2.3 × 10(-5) mol/l.
价 格:¥电议型 号:T68138产 地:中国大陆
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T671384-(Difluoromethoxy)-3-hydroxybenzaldehyde;化合物 4-(Difluoromethoxy)-3-hydroxybenzaldehyde4-(Difluorome
4-(Difluoromethoxy)-3-hydroxybenzaldehyde is a useful organic compound for research related to life sciences. The catalog number is T67138 and the CAS number is 151103-08-1.
价 格:¥电议型 号:T67138产 地:中国大陆
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T66138(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclopentylacetic acid;化合物 (S)-2-((tert-Butoxycarbonyl)amino)-2
(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclopentylacetic acid is a useful organic compound for research related to life sciences. The catalog number is T66138 and the CAS number is 109183-72-4.
价 格:¥电议型 号:T66138产 地:中国大陆
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T65138DL-Lysine dihydrochloride;化合物 DL-Lysine dihydrochlorideDL-Lysine dihydrochloride
DL-Lysine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65138 and the CAS number is 617-68-5.
价 格:¥电议型 号:T65138产 地:中国大陆
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T6442CH5138303化合物CH5138303gastric cancer|||inhibit|||CH-5138303
CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.
价 格:¥电议型 号:T6442产 地:中国大陆
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T64138Cap-dependent endonuclease-IN-16;化合物 Cap-dependent endonuclease-IN-16Cap-dependent endonuclease-IN-1
Cap-dependent endonuclease-IN-16 is a pyridone polycyclic derivative and a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-16 shows potential for influenza studies.
价 格:¥电议型 号:T64138产 地:中国大陆
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T63976AZ13824374;化合物 AZ13824374AZ13824374
AZ13824374 is a potent and selective ATAD2 inhibitor with anti-proliferative effects in breast cancer. pIC50 values for AZ13824374 against ATAD2 in the ATAD2 FRET and ATAD2 NanoBRET assays were 8.2 and 6.2, respectively.
价 格:¥电议型 号:T63976产 地:中国大陆
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T63138PRMT5-IN-16;化合物 PRMT5-IN-16PRMT5-IN-16
PRMT5-IN-16 (Compound 20) is a PRMT5 inhibitor with antitumour effects. PRMT5, a protein arginine methyltransferase, is a novel anti-tumour target associated with epigenetic modifications.
价 格:¥电议型 号:T63138产 地:中国大陆
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T63036CP-113818;化合物 CP-113818CP-113818
CP-113818 is a potent inhibitor of cholesterol acyltransferase (ACAT) and can be used to study Alzheimer´s disease.
价 格:¥电议型 号:T63036产 地:中国大陆
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T62168ML138;化合物 ML138ML138
ML138 is a probe for MLPCN, an agonist of the κ opioid receptor.
价 格:¥电议型 号:T62168产 地:中国大陆
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T62138Renin inhibitor-1;化合物 Renin inhibitor-1Renin inhibitor-1
Renin inhibitor-1 (compound 26) is a potent, orally active renin inhibitor capable of acting on rh-renin (IC50: 0.9 nM) and hPRA (IC50: 1.8 nM). renal disease.
价 格:¥电议型 号:T62138产 地:中国大陆
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T61666SUN13837;化合物 SUN13837SUN13837
SUN13837 is an orally active, potent modulator of the fibroblast growth factor receptor (FGFR) with the ability to penetrate the blood-brain barrier (BBB). It exhibits neuroprotective activity and holds promise for furthering research on neurodegenerative diseases [1].
价 格:¥电议型 号:T61666产 地:中国大陆
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T61389TGFβ1-IN-1;TGFβ1 抑制剂1TGFβ1-IN-1
TGFβ1-IN-1 is an orally active TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrotic markers (α-SMA and fibronectin) and can be used for the study of cancer and autoimmune diseases.
价 格:¥电议型 号:T61389产 地:中国大陆
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T61388hAChE/Aβ1-42-IN-1;化合物 hAChE/Aβ1-42-IN-1hAChE/Aβ1-42-IN-1
Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and excellent brain-blood barrier (BBB) penetration with a broad safety margin. This compound shows promise for Alzheimer´s disease (AD) research [1].
价 格:¥电议型 号:T61388产 地:中国大陆
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T61387Bromodomain inhibitor-10;化合物 Bromodomain inhibitor-10Bromodomain inhibitor-10
Bromodomain inhibitor-10 (compound 128) is a highly potent inhibitor of bromodomain activity. It exhibits strong binding affinity with K d values of 15.0 nM and 2500 nM for BRD4-1 and BRD4-2, respectively. Furthermore, Bromodomain inhibitor-10 effectively inhibits the production of IL12p40 [1].
价 格:¥电议型 号:T61387产 地:中国大陆
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T61386CXCR2 antagonist 2;化合物 CXCR2 antagonist 2CXCR2 antagonist 2
CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunotherapy with an IC 50 value of 95 nM.
价 格:¥电议型 号:T61386产 地:中国大陆
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T61385IDO1/TDO-IN-1;化合物 IDO1/TDO-IN-1IDO1/TDO-IN-1
IDO1/TDO-IN-1 (30) is a highly effective inhibitor that targets both IDO1 and TDO enzymes with uncompetitive (Ki = 0.23 μM) and competitive (Ki = 0.73 μM) mechanisms, respectively. This compound, IDO1/TDO-IN-1 (30), exhibits a significant capacity to induce cell apoptosis via the potential mitochondria-mediated Bcl-2/Bax pathway [1].
价 格:¥电议型 号:T61385产 地:中国大陆
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T61384hCAIX/XII-IN-4;化合物 hCAIX/XII-IN-4hCAIX/XII-IN-4
hCAIX/XII-IN-4 (compound 6c) is a highly potent inhibitor of CAIX/XII. It exhibits Ki values of 4.5 nM, 23.6 nM, >10000 nM, and >10000 nM for CAXII, CAIX, CAI, and CAⅡ, respectively [1].
价 格:¥电议型 号:T61384产 地:中国大陆
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T61383Diaziquone;地吖醌NSC 182986;NSC 182986
Diaziquone (NSC-182986) is a water-soluble synthetic azacyclic benzoquinone that enhances penetration of the blood-brain barrier, has antitumor activity, and is used in the treatment of extreme renal failure.
价 格:¥电议型 号:T61383产 地:中国大陆