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T81382PROTAC BRD9 Degrader-7；化合物 PROTAC BRD9 Degrader-7PROTAC BRD9 Degrader-7
PROTAC BRD9 Degrader-7 is a selective and orally active BRD9 degrader with a DC50 of 1.02 nM and demonstrates superior pharmacokinetics, evidenced by a Cmax of 3436.95 ng/mL [1].
价 格：￥电议型 号：T81382产 地：中国大陆
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T81381PROTAC eDHFR Degrader-1；化合物 PROTAC eDHFR Degrader-1PROTAC eDHFR Degrader-1
PROTAC eDHFR Degrader-1 is a potent degrader targeting eDHFR-YFP and various proteins of interest (POIs), such as YFP and Luciferase [1].
价 格：￥电议型 号：T81381产 地：中国大陆
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T81380PROTAC EGFR degrader 7 diTFA；化合物 PROTAC EGFR degrader 7 diTFAPROTAC EGFR degrader 7 diTFA
PROTAC EGFR degrader 7 (compound 13b) is a potent, selective, CRBN-recruiting EGFRL858R/T790M degrader with a DC50 of 13.2 nM. It effectively inhibits proliferation of NCI-H1975 cells with an IC50 of 46.82 nM, induces apoptosis, and causes a G2/M phase arrest in these cells. Demonstrating antitumor activity, this compound is applicable in non-small cell lung cancer (NSCLC) research.
价 格：￥电议型 号：T81380产 地：中国大陆
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T8138Phenazine methylsulfate5-甲基吩嗪硫酸甲酯5-甲基吩嗪硫酸甲酯|||Phenazine methosulfate
Phenazine methylsulfate is anti-bacterial agents.
价 格：￥电议型 号：T8138产 地：中国大陆
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T81138SNNF(N-Me)GA(N-Me)ILSS；化合物 SNNF(N-Me)GA(N-Me)ILSSSNNF(N-Me)GA(N-Me)ILSS
SNNF(N-Me)GA(N-Me)ILSS is a biologically active peptide comprising double N-methylated derivatives of an amyloidogenic and cytotoxic partial IAPP sequence.
价 格：￥电议型 号：T81138产 地：中国大陆
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T80138(D-Arg8)-Inotocin；化合物 (D-Arg8)-Inotocin(D-Arg8)-Inotocin
´(D-Arg8)-Inotocin is a potent, selective, and competitive antagonist of the vasopressin receptor (V 1a R), exhibiting a binding affinity (K i) of 1.3 nM. It demonstrates over 3000-fold selectivity for the human V1aR compared to the OTR, V1bR, and V2R subtypes [1].´
价 格：￥电议型 号：T80138产 地：中国大陆
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T79138Antitumor agent-100 hydrochloride；化合物 Antitumor agent-100 hydrochlorideAntitumor agent-100 hydrochlo
Antitumor agent-100 hydrochloride (compound A6), serving as both an apoptosis inducer and molecular glue, exhibits superior anti-tumor activity [1].
价 格：￥电议型 号：T79138产 地：中国大陆
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T79040TRV-1387；化合物 TRV-1387TRV-1387
TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].
价 格：￥电议型 号：T79040产 地：中国大陆
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T7884NS 1738；化合物NS 1738NSC 213859；NSC 213859
NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)
价 格：￥电议型 号：T7884产 地：中国大陆
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T78144NCGC00138783 TFA；化合物 NCGC00138783 TFANCGC00138783 TFA
NCGC00138783 TFA acts as a selective inhibitor of the CD47/SIRPα axis, exhibiting an inhibitory concentration (IC50) of 50 μM. This compound effectively obstructs the interaction between CD47 and SIRPα [1] [2].
价 格：￥电议型 号：T78144产 地：中国大陆
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T78138SIC5-6；化合物 SIC5-6SIC5-6
SIC5-6 is a potent inhibitor of Separase, a substantial cysteine protease implicated in critical cellular processes such as chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, as well as spindle stabilization and elongation. Given its overexpression in many solid cancers, Separase presents an attractive target for chemotherapy [1].
价 格：￥电议型 号：T78138产 地：中国大陆
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T77138Ragifilimab；拉格芙利单抗INCAGN-01876|||INCAGN-1876|||CM-701；INCAGN-01876|||INCAGN-1876|||CM-701
Ragifilimab (INCAGN-1876) is an agonist monoclonal antibody targeting glucocorticoid-induced TNFR-associated protein (GITR). Ragifilimab can be used in the study of advanced or metastatic solid tumors.
价 格：￥电议型 号：T77138产 地：中国大陆
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T76138Phosphodiesterase；化合物 PhosphodiesterasePhosphodiesterase
Phosphodiesterase (PDE), an enzyme capable of catalyzing the hydrolysis of the 3´ ring phosphate bond in cyclic nucleotides, plays a crucial role in biochemical research and acts as a vital regulator in signal transduction processes involving the second messenger molecules cAMP and cGMP. Distinguished by their specificity to cyclic nucleotides, PDEs are categorized into different types ranging from PDE1 to PDE11, presenting potential significance in the study and treatment of various disea
价 格：￥电议型 号：T76138产 地：中国大陆
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T75416alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)；化合物 alpha-1,3-N-Acetylgalactosaminyltransferase
Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1].
价 格：￥电议型 号：T75416产 地：中国大陆
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T75138Lipid 14；化合物 Lipid 14Lipid 14
Lipid 14, a potent ionizable compound, is essential for synthesizing lipid nanoparticles (LNPs) [1].
价 格：￥电议型 号：T75138产 地：中国大陆
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T74775Antibacterial agent 138；化合物 Antibacterial agent 138Antibacterial agent 138
Antibacterial agent 138 exhibits superior efficacy against multi-drug resistant bacteria by inhibiting their protein synthesis and affecting bacterial cell walls [1].
价 格：￥电议型 号：T74775产 地：中国大陆
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T74138PROTAC Bcl-xL degrader-2；化合物 PROTAC Bcl-xL degrader-2PROTAC Bcl-xL degrader-2
PROTAC Bcl-xL degrader-2, based on von Hippel-Lindau ligand, is a potent degrader of Bcl-xL (a Bcl-2 family member), demonstrating an IC 50 of 0.6 nM.
价 格：￥电议型 号：T74138产 地：中国大陆
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T73560I-138；化合物I-138I-138
I-138 is an orally active and potent reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells.
价 格：￥电议型 号：T73560产 地：中国大陆
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T72930NCGC00138783；化合物 NCGC00138783NCGC00138783
NCGC00138783 is a selective inhibitor of the CD47/SIRPα axis, demonstrating its efficacy by directly blocking the interaction between CD47 and SIRPα, with an inhibitory concentration (IC 50) of 50 ?M.
价 格：￥电议型 号：T72930产 地：中国大陆
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T72138Mitochondrial respiration-IN-2；化合物 Mitochondrial respiration-IN-2Mitochondrial respiration-IN-2
Mitochondrial respiration-IN-2, a fluorine derivative of Virginiamycin M1, inhibits the mitochondrial translation of glioblastoma stem cells [1].
价 格：￥电议型 号：T72138产 地：中国大陆
