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  • T4176rac-BHFF；化合物rac-BHFF(R,S)-BHFF；(R,S)-BHFF

    rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo and is orally active.

    价 格：￥电议型 号：T4176产 地：中国大陆

  • T41176PARPYnD；PARPYnDPARPYnD

    PARPYnD is a potent photoaffinity probe for poly(ADP-ribose) polymerase (PARP) (IC50 values for PARP2, PARP1 and PARP6 are 6, 38 and 230 nM, respectively). PARPYnD labels PARP1 and PARP2 in the cell when an N3 functionalized fluorescent probe is attached and can inhibit isolated PARP6.

    价 格：￥电议型 号：T41176产 地：中国大陆

  • T40358Ensitrelvir fumarateEnsitrelvir fumarateS-217622 fumarate

    Ensitrelvir (S-217622) fumarate is a novel orally active inhibitor, targeting the SARS-CoV-2 3CL protease (IC50 = 13 nM). It demonstrates non-covalent and non-peptidic characteristics. This compound represents a pioneering advancement in the development of effective antiviral agents against the SARS-CoV-2 virus.

    价 格：￥电议型 号：T40358产 地：中国大陆

  • T40276GS-621763；化合物GS-621763GS-621763

    GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.

    价 格：￥电议型 号：T40276产 地：中国大陆

  • T40176MrgprX2 antagonist-5MrgprX2 antagonist-5MrgprX2 antagonist-5

    MrgprX2 antagonist-5, which acts as a potent antagonist of MrgprX2. It exhibits the ability to effectively inhibit the activity of MrgprX2, making it an ideal candidate for research related to inflammatory skin disorders.

    价 格：￥电议型 号：T40176产 地：中国大陆

  • T39707AS-1763；化合物AS-1763AS-1763

    AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.

    价 格：￥电议型 号：T39707产 地：中国大陆

  • T39176PB28；PB28PB28

    PB28 is a cyclohexylpiperazine derivative that functions as a potent and highly selective agonist of the sigma 2 (σ2) receptor, exhibiting a Ki (binding affinity) of 0.68 nM. At the same time, PB28 acts as an antagonist of the sigma 1 (σ1) receptor, with a Ki of 0.38 nM. PB28 demonstrates a lower affinity for other receptors. It effectively inhibits electrically evoked twitch in both the guinea pig bladder (EC50 value of 2.62 μM) and ileum (EC50 value of 3.96 μM). Moreover, PB28 exhibits the abi

    价 格：￥电议型 号：T39176产 地：中国大陆

  • T38983Dazucorilant；DazucorilantCORT113176；CORT113176

    Dazucorilant (CORT113176) is a non-steroidal glucocorticoid receptor (GR) modulator characterized by its high affinity and selectivity. With an impressive K i value of ＜1 nM in vitro, Dazucorilant proves to be an exceptional compound for investigating neurological disorders.

    价 格：￥电议型 号：T38983产 地：中国大陆

  • T38787ER176；ER176ER176

    ER176 is a novel PET radioligand utilized for the visualization of 18 kDa translocator protein (TSPO), a neuroinflammation biomarker, marking the advancement in imaging technology.

    价 格：￥电议型 号：T38787产 地：中国大陆

  • T38176Muramic acid；Muramic acidMuramic acid

    Muramic acid is a prevalent constituent found in the cell walls of Gram-positive bacteria, serving as a distinguishing marker for such bacteria[1].

    价 格：￥电议型 号：T38176产 地：中国大陆

  • T38013Sonlicromanol hydrochloride；Sonlicromanol 盐酸盐KH 176 hydrochloride；KH 176 hydrochloride

    Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases.

    价 格：￥电议型 号：T38013产 地：中国大陆

  • T37176Edoxaban impurity 6；Edoxaban impurity 6Edoxaban impurity 6

    Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2].

    价 格：￥电议型 号：T37176产 地：中国大陆

  • T3643HMN-176；化合物HMN176HMN-176

    HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).

    价 格：￥电议型 号：T3643产 地：中国大陆

  • T36176AMK (hydrochloride)；AMK (hydrochloride)AMK (hydrochloride)

    AMK is an active metabolite of the neurohormone melatonin .1,2,3,4It is formed from melatoninviathe metabolic intermediate AFMK that is then deformylated by catalase or formamidase.5,6AMK scavenges singlet oxygenin vitrowhen used at a concentration of 200 μM.1It inhibits the epinephrine- and arachidonic acid-induced production of prostaglandin E2and PGD2in ovine seminal vesicle microsomes in a concentration- and time-dependent manner, as well as LPS-induced increases in COX-2 levels in RAW 264.7

    价 格：￥电议型 号：T36176产 地：中国大陆

  • T35973Cholesterol-5α,6α-epoxide；胆固醇-5Α,6Α-环氧化物Epoxycholesterol|||5α,6α-epoxy Cholestanol|||NSC 18176；Epoxy

    Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE application.

    价 格：￥电议型 号：T35973产 地：中国大陆

  • T35856BMS-986176；化合物BMS-986176BMS-986176

    AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).

    价 格：￥电议型 号：T35856产 地：中国大陆

  • T3581KS176；化合物KS176KS176

    KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MRP1.

    价 格：￥电议型 号：T3581产 地：中国大陆

  • T35176Xibenolol；化合物 T35176Xibenololum；Xibenololum

    Xibenolol is a biochmeical.

    价 格：￥电议型 号：T35176产 地：中国大陆

  • T35033Vamicamide；戊米胺FK 176|||FK-176|||FK176；FK 176|||FK-176|||FK176

    Vamicamide (FK 176) is a novel anticholinergic compound. Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg (p.o.) or higher and inhibits cataleptic convulsions in mice at 100 mg/kg.

    价 格：￥电议型 号：T35033产 地：中国大陆

  • T3435Vicriviroc maleate；维立韦罗马来酸盐SCH-D (maleate)|||SCH-417690 (maleate)；维立韦罗马来酸盐|||SCH-D (maleate)|||SCH-4

    Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.

    价 格：￥电议型 号：T3435产 地：中国大陆

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