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T60731Mitobronitol;化合物 MitobronitolMitobronitol
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol. Mitobronitol is an anticancer agent classified as an alkylating agent. Mitobronitol shows myelosuppression effect that significantly reduced risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia [1] [2].
价 格:¥电议型 号:T60731产 地:中国大陆
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T60730BA38017;化合物 BA38017BA38017
BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].
价 格:¥电议型 号:T60730产 地:中国大陆
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T6073OG-L002;化合物OG-L002OG-L002
OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.
价 格:¥电议型 号:T6073产 地:中国大陆
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T6072LBGT226;化合物BGT226BGT226 free base|||NVP-BGT226;BGT226 free base|||NVP-BGT226
BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
价 格:¥电议型 号:T6072L产 地:中国大陆
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T60729EGFR-IN-67;化合物 EGFR-IN-67EGFR-IN-67
EGFR-IN-67 (Compound 7d) is a potent inhibitor of EGFR with anticancer activity (IC 50 = 0.34 μM) [1].
价 格:¥电议型 号:T60729产 地:中国大陆
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T60728M1 ligand 1;化合物 M1 ligand 1M1 ligand 1
M1 ligand 1 (compound 3b-b) is a N-desmethyl congener of arecoline derivative that is a muscarinic acetylcholine receptor M1 ligand. M1 ligand 1 is able to be used as PET (positron emission tomography) radiotracer [1].
价 格:¥电议型 号:T60728产 地:中国大陆
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T60727B-Raf IN 8;化合物 B-Raf IN 8B-Raf IN 8
B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC 50 = 70.65 nM). B-Raf IN 8 shows antitumor activity which has IC 50 values of 9.78, 13.78, 18.52 and 29.85 μM against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells [1].
价 格:¥电议型 号:T60727产 地:中国大陆
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T60726OYYF-175;化合物 OYYF-175OYYF-175
OYYF-175 is an antimicrobial antifolate. OYYF-175 exhibits potent broad-spectrum antibacterial activities, especially against multi-drug resistant Gram-Negative-strains. OYYF-175 is an inhibitor of dihydrofolate reductase (DHFR) with an IC 50 of 2.36 nM for Escherichia coli DHFR.
价 格:¥电议型 号:T60726产 地:中国大陆
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T60725PRMT5-IN-10;化合物 PRMT5-IN-10PRMT5-IN-10
PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.
价 格:¥电议型 号:T60725产 地:中国大陆
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T60724URAT1 inhibitor 3;化合物 URAT1 inhibitor 3URAT1 inhibitor 3
URAT1 inhibitor 3 is a potent, orally active, selective inhibitor of URAT1(IC 50 = 0.8 nM). URAT1 inhibitor 3 shows urate-lowering efficacy that can be used in gout and hyperuricemi research [1].
价 格:¥电议型 号:T60724产 地:中国大陆
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T60723CYP1B1-IN-1;化合物 CYP1B1-IN-1CYP1B1-IN-1
CYP1B1-IN-1 (Compound 9e) is a selective inhibitor of cytochrome P450 1B1 (CYP1B1) (IC 50 = 0.49 nM) [1].
价 格:¥电议型 号:T60723产 地:中国大陆
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T60722Prohibitin ligand 1;化合物 Prohibitin ligand 1Prohibitin ligand 1
Prohibitin ligand 1 (Compound 22i) is a cardioprotectant prohibitin ligand that exhibits in vitro cardioprotectant activities at nanomolar concentrations. Prohibitin ligand 1 induces the pro-survival factor STAT3 phosphorylation [1].
价 格:¥电议型 号:T60722产 地:中国大陆
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T60720AChE/BChE-IN-4;化合物 AChE/BChE-IN-4AChE/BChE-IN-4
AChE/BChE-IN-4 (BMC-3) is an AChE and BChE dual inhibitor that can cross the BBB. The IC 50 values of AChE/BChE-IN-4 for human AChE (hAChE) and human BChE (hBChE) are 792 nM and 2.2 nM, respectively[1].
价 格:¥电议型 号:T60720产 地:中国大陆
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T6072BGT226 maleate;化合物BGT226BGT226|||NVP-BGT226 (maleate)|||NVP-BGT226;BGT226|||NVP-BGT226 (maleate)|||N
BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .
价 格:¥电议型 号:T6072产 地:中国大陆
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T60719AR antagonist 3;化合物 AR antagonist 3AR antagonist 3
When administered intratumorally, AR antagonist 3 shows effective inhibition on the growth of tumor. AR antagonist 3 is a potent and selective antagonist of androgen receptor (AR) with an IC 50 of 0.47 μM. AR antagonist 3 dose-dependently decrease the FRET signal with an IC50 of 18.05 μM [1].
价 格:¥电议型 号:T60719产 地:中国大陆
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T607183-IN-PP1;化合物 3-IN-PP13-IN-PP1
3-IN-PP1, a potent protein kinase D (PKD) inhibitor, exhibits pan-PKD inhibitory activity with IC50 values of 108 nM for PKD1, 94 nM for PKD2, and 108 nM for PKD3. Additionally, it serves as a broad-spectrum anticancer agent by inhibiting the growth of various tumor cells. 3-IN-PP1 is utilized in cancer research [1].
价 格:¥电议型 号:T60718产 地:中国大陆
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T60717Phenolphthalol;化合物 PhenolphthalolPhenolphthalol
Phenolphthalol is estrogenically active which is also a laxative in drug preparations [1].
价 格:¥电议型 号:T60717产 地:中国大陆
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T60716Antitubercular agent-28;化合物 Antitubercular agent-28Antitubercular agent-28
Antitubercular agent-28 (compound 2) has antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 is a potent antitubercular agent with an MIC value of 4.5 μM, an IC 50 value of 1.5 μM, and an IC 90 value of 2.5 μM. Antitubercular agent-28 shows effective intracellular antimycobacterial activity with low cytotoxicity [1].
价 格:¥电议型 号:T60716产 地:中国大陆
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T60715α-Glucosidase-IN-4;α-Glucosidase抑制剂4α-Glucosidase-IN-4
α-Glucosidase-IN-4 is a potent α-glucosidase inhibitor with antihypertensive and hypoglycemic activity.
价 格:¥电议型 号:T60715产 地:中国大陆
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T60714gp120-IN-2;化合物 gp120-IN-2gp120-IN-2
gp120-IN-2 (compound 4i) exhibits anti-HIV-1 activity which is a potent inhibitor of HIV-1 gp120 with an IC 50 of 7.5 μM and CC 50 of 112.93 μM. gp120-IN-2 dose-dependently shows cytotoxicity in SUP-T1 cells [1].
价 格:¥电议型 号:T60714产 地:中国大陆