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T60713TK-129;化合物 TK-129TK-129
TK-129 is an orally active, potent inhibitor of KDM5B with IC 50 of 44 nM that is low-toxicity. TK-129 shows cardioprotective effects by inhibiting KDM5B and blocking the KDM5B -associated Wnt pathway. TK-129 can be used in cardiovascular disease studies which reduce isoprenaline-induced myocardial remodelling and fibrosis in vivo as well as reduce ang II-induced activation of cardiac fibroblasts in vitro [1].
价 格:¥电议型 号:T60713产 地:中国大陆
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T60712MAO-B-IN-17;MAO-B抑制剂17MAO-B-IN-17
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson´s.
价 格:¥电议型 号:T60712产 地:中国大陆
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T60711Avibactam sodium hydrate;化合物 Avibactam sodium hydrateAvibactam sodium hydrate
Avibactam sodium hydrate (NXL-104 hydrate) is a covalent and reversible inhibitor of β-lactamase that does not contain a β-lactam core. Avibactam sodium hydrate inhibits β-lactamase CTX-M-15 and TEM-1 with IC 50 s of 5 nM and 8 nM, respectively.
价 格:¥电议型 号:T60711产 地:中国大陆
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T6071Parbendazole;帕苯咪唑SKF 29044;SKF 29044|||帕苯咪唑
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
价 格:¥电议型 号:T6071产 地:中国大陆
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T60709Acyclovir monophosphate;化合物 Acyclovir monophosphateAcyclovir monophosphate
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agen which also has antitumor activity. Acyclovir monophosphate blocks synthesis of DNA by inhibiting the viral DNA polymerase and terminates the chain elongation of the viral DNA [1] [2].
价 格:¥电议型 号:T60709产 地:中国大陆
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T60708Cedazuridine hydrochloride;化合物 Cedazuridine hydrochlorideCedazuridine hydrochloride
Cedazuridine (E7727) (Compound 7a) hydrochloride can be used for researching of cancer that is an orally active inhibitor of cytidine deaminase (CDA) (IC 50 = 0.4 μM) [1].
价 格:¥电议型 号:T60708产 地:中国大陆
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T60707Quinupramine;奎纽帕明LM 208;LM 208
Quinupramine (LM 208) is an orally available classical tricyclic antidepressant compound with a strong affinity for muscarinic and 5-HT receptors.Quinupramine crosses the central nervous system and can be used in the study of neurologic disorders.
价 格:¥电议型 号:T60707产 地:中国大陆
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T60706LP-284;化合物 LP-284LP-284
LP-284 kills solid tumours. LP-284 is a potent DNA alkylating agent that can be used in the hematologic cancers studies with compromised DNA repair, for example, mantle cell lymphoma (MCL) [1] [2].
价 格:¥电议型 号:T60706产 地:中国大陆
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T60705Flupirtine;化合物 FlupirtineFlupirtine
Flupirtine(D 9998) is a selective neuronal potassium channel opener as well as shows properties of NMDA receptor antagonist.
价 格:¥电议型 号:T60705产 地:中国大陆
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T60704Loxoprofen sodium (dihydrate);化合物 Loxoprofen sodium (dihydrate)Loxoprofen sodium (dihydrate)
Loxoprofen sodium dihydrate is a non-steroidal, orally active anti-inflammatory agent that has analgesic and anti-pyretic properties. Loxoprofen sodium dihydrate exhibits antitumor activity which also can reduce atherosclerosis. Loxoprofen sodium dihydrate is a nonselective inhibitor of COX with IC 50 s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively [1] [2] [3] [4].
价 格:¥电议型 号:T60704产 地:中国大陆
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T60702Globosuxanthone A;化合物 Globosuxanthone AGlobosuxanthone A
Globosuxanthone A is a dihydroxanthenone with anticancer activity. Globosuxanthone A shows obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively [1] [2].
价 格:¥电议型 号:T60702产 地:中国大陆
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T60701Fludarabine-Cl;化合物 Fludarabine-ClFludarabine-Cl
Fludarabine-Cl shows inhibition effect on RNA adenosine deaminase 1(ADAR1) that can be used for preventing and/or treating diseases related with cancer or tumor [1].
价 格:¥电议型 号:T60701产 地:中国大陆
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T60700Butabindide;化合物 ButabindideButabindide
Butabindide (UCL-1397) is a potent, selective inhibitor of tripeptidvl peptidase II (TPP II) with Ki values of 10 μM and 7 nM for TPP I and TPP II, respectively. Butabindide inhibits TPP II in order to protect CCK-8 against inactivation [1] [2].
价 格:¥电议型 号:T60700产 地:中国大陆
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T6070(E/Z)-Rigosertib sodium;(E/Z)-Rigosertib 钠盐(E/Z) ON-01910 sodium;N-[2-甲氧基-5-[[[2-(2,4,6-三甲氧基苯基)乙烯基]磺
ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity.
价 格:¥电议型 号:T6070产 地:中国大陆
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T60607Dasotraline;化合物 DasotralineDasotraline
Dasotraline is a triple reuptake inhibitor that blocks dopamine(DA), norepinephrine(NE), and serotonin [5-hydroxytryptamine (5-HT)] transporters with IC 50 values of 4, 6, and 11 nM, respectively. Dasotraline represents a potential new class of antidepressant agents.
价 格:¥电议型 号:T60607产 地:中国大陆
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T6048Dalcetrapib;达塞曲匹JTT-705|||RO4607381;JTT-705|||达塞曲匹|||RO4607381
Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
价 格:¥电议型 号:T6048产 地:中国大陆
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T5S1607Morusin;桑辛素Mulberrochromene;Mulberrochromene|||桑辛素
1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti-oxidant and anti-inflammatory effects.
价 格:¥电议型 号:T5S1607产 地:中国大陆
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T5607Geranyl acetate;乙酸香叶酯Geranyl acetate
Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.
价 格:¥电议型 号:T5607产 地:中国大陆
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T4607CAY 10465;化合物CAY10465CAY10465|||CAY10465 Exclusive;CAY10465|||CAY10465 Exclusive
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
价 格:¥电议型 号:T4607产 地:中国大陆
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T406072,4,6-Trimethylphenol;2,4,6-三甲基苯酚Mesitol;Mesitol
2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.
价 格:¥电议型 号:T40607产 地:中国大陆