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T39607NLRP3 modulators 1NLRP3 modulators 1NLRP3 modulators 1
NLRP3 modulators 1 (WO2017184746A1, compound 107) is a potent modulator of NLRP3, capable of agonizing or partially agonizing the activity of NLRP3. This compound proves valuable in investigating conditions, diseases, or disorders where a reduction in LRP3 activity plays a role in the pathology.
价 格:¥电议型 号:T39607产 地:中国大陆
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T38607Etoposide phosphate disodiumEtoposide phosphate disodiumBMY-40481 disodium|||Etoposide phosphate dis
Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, functions as a potent chemotherapeutic agent by selectively inhibiting topoisomerase II, hindering the re-ligation of DNA strands. It is regarded as the active equivalent of etoposide, effectively inducing cell cycle arrest, apoptosis, and autophagy in cancer cells.
价 格:¥电议型 号:T38607产 地:中国大陆
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T37607Rhodamine B isothiocyanate (mixed isomers);Rhodamine B isothiocyanate (mixed isomers)Rhodamine B iso
Rhodamine B isothiocyanate (RITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy. It displays excitation/emission maxima of 570/595 nm, respectively, and can be used in conjunction with immunohistochemistry for multi-labeling studies. It has also been used as an anterograde and retrograde tracer in neurons and in nanoparticles to detect apoptosis.
价 格:¥电议型 号:T37607产 地:中国大陆
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T36607(±)8-HDHA;(±)8-HDHA(±)8-HDHA
(±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
价 格:¥电议型 号:T36607产 地:中国大陆
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T36079Tripelargonin;化合物 TripelargoninTripelargonin
Tripelargonin is a triacylglycerol that contains nonanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in Schizochytrium biomass.1 Tripelargonin increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in newborn rhesus monkeys.2
价 格:¥电议型 号:T36079产 地:中国大陆
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T36078D-Xylofuranose, 1,2,3,5-tetraacetate;1,2,3,5-Tetra-O-acetyl-D-xylofuranoseD-Xylofuranose, 1,2,3,5-te
1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.
价 格:¥电议型 号:T36078产 地:中国大陆
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T36077cis-Parinaric Acid;cis-Parinaric Acidcis-Parinaric Acid|||α-Parinaric Acid;cis-Parinaric Acid|||α-Pa
cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained wit
价 格:¥电议型 号:T36077产 地:中国大陆
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T36076Ciprofibrate impurity A;Ciprofibrate impurity ACiprofibrate impurity A
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1].
价 格:¥电议型 号:T36076产 地:中国大陆
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T36075Cholic Acid anilideCholic Acid anilideCholic Acid anilide
Cholic acid anilide is a synthetic bile acid and derivative of cholic acid that inhibits the germination of C. difficile strain R20291 spores in vitro (IC50 = 1.8 μM).
价 格:¥电议型 号:T36075产 地:中国大陆
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T36074S-NEPC;S-NEPCS-NEPC
Cytochrome P450 metabolites of arachidonic acid, such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding DiHETrEs thereby diminishing their activity. Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation. S-NEPC is a colorimetric substrate used to measure sEH activity. It also is
价 格:¥电议型 号:T36074产 地:中国大陆
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T36073S-Acetyl-L-glutathione;S-Acetyl-L-glutathioneS-Acetyl-L-glutathione
S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases
价 格:¥电议型 号:T36073产 地:中国大陆
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T36072Skyrin;SkyrinEndothianin|||Rhodophyscin;Endothianin|||Rhodophyscin
Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 μM, skyrin reduces both glucagon-stimulated cAMP production and glycogenolysis. It does not interfere with epinephrine or glucagon-like peptide 1 effects on these parameters.[1]
价 格:¥电议型 号:T36072产 地:中国大陆
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T36071Silodosin Glucuronide (sodium salt);Silodosin Glucuronide (sodium salt)Silodosin Glucuronide (sodium
Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.
价 格:¥电议型 号:T36071产 地:中国大陆
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T36070(±)5(6)-EET;(±)5(6)-EET(±)5(6)-EET
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5(6)-EET has been implicated in the mobilization of calcium and hormone secretion. 5(6)-EET is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhib
价 格:¥电议型 号:T36070产 地:中国大陆
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T3607Leucomycin;吉他霉素Kitasamycin|||Leucomycin V|||Turimycin;吉他霉素|||Kitasamycin|||Leucomycin V|||Turimycin
Leucomycin (Turimycin) is a macrolide antibiotic.
价 格:¥电议型 号:T3607产 地:中国大陆
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T34784TAN67;化合物 T34784SB-205607 dihydrobromide|||SB 205607 dihydrobromide|||SB205607 dihydrobromide|||TAN-
TAN67 is the first effective selective non-peptide delta1 opioid receptor.
价 格:¥电议型 号:T34784产 地:中国大陆
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T34607Selenolanthionine;化合物 T34607Selenolanthionine
Selenolanthionine is the major water-soluble selenium compound in the selenium tolerant plant Cardamine violifolia.
价 格:¥电议型 号:T34607产 地:中国大陆
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T33636Neospiran;化合物 T33636NSC16071|||NSC 16071|||NSC-16071;NSC16071|||NSC 16071|||NSC-16071
Neospiran can be used in intracardial injections.
价 格:¥电议型 号:T33636产 地:中国大陆
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T33607NBI-34041;化合物 T33607NBI34041|||SB 723620|||SB-723620|||SB723620;NBI34041|||SB 723620|||SB-723620|||S
NBI-34041 is an effective and high-affinity CRF1 receptor antagonist that effectively reduces endocrine responses to CRF(1) receptor-mediated pharmacological and behavioral challenges.
价 格:¥电议型 号:T33607产 地:中国大陆
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T32607Lavendomycin;化合物 T32607Antibiotic FR 900201|||FR-900201|||FR 900201|||FR900201;Antibiotic FR 900201|
Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.
价 格:¥电议型 号:T32607产 地:中国大陆