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  • T6441CGS 21680 Hydrochloride；化合物CGS 21680 HClCGS 21680 HCl；CGS 21680 HCl

    CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.

    价 格：￥电议型 号：T6441产 地：中国大陆

  • T63680Cap-dependent endonuclease-IN-11；化合物 Cap-dependent endonuclease-IN-11Cap-dependent endonuclease-IN-1

    Cap-dependent endonuclease-IN-11 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-11 has shown research potential for viral infections.

    价 格：￥电议型 号：T63680产 地：中国大陆

  • T6338PHA-680632；化合物PHA-680632PHA 680632|||PHA680632；PHA 680632|||PHA680632

    PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.

    价 格：￥电议型 号：T6338产 地：中国大陆

  • T62680(R)-MLT-985；化合物 (R)-MLT-985(R)-MLT-985

    (R)-MLT-985 (compound 11) is a potent inhibitor of MALT1 protease (IC50: 3 nM). (R)-MLT-985 has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells.(R)-MLT-985 inhibits growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.

    价 格：￥电议型 号：T62680产 地：中国大陆

  • T61680AKT-IN-5；化合物 AKT-IN-5AKT-IN-5

    AKT-IN-5 (Example 8) is a chemical compound known as an Akt inhibitor, specifically targeting Akt1 and Akt2. Its potency is reflected in IC50 values of 450 nM and 400 nM for Akt1 and Akt2, respectively [1].

    价 格：￥电议型 号：T61680产 地：中国大陆

  • T60680Tegaserod；替加色罗Tegaserod

    Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has antitumor activity and is used in the treatment of irritable bowel syndrome (IBS).

    价 格：￥电议型 号：T60680产 地：中国大陆

  • T5680Aloin(mixture of A&B)芦荟苷芦荟素,葡糖基蒽酮,芦荟大黄素甙|||芦荟苷

    ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.

    价 格：￥电议型 号：T5680产 地：中国大陆

  • T5047PD-168077 maleate；化合物PD-168077 maleatePD-168077 maleate

    PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)

    价 格：￥电议型 号：T5047产 地：中国大陆

  • T4680HC-067047；化合物HC-067047HC067047；HC067047

    HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .

    价 格：￥电议型 号：T4680产 地：中国大陆

  • T40680[Tyr11]-Somatostatin；[Tyr11]-Somatostatin[Tyr11]-Somatostatin；[Tyr11]-Somatostatin

    [Tyr11]-Somatostatin is a neuroactive peptide utilized in proteomics research. It belongs to a class of neuroactive substances that play a role in modulating retinal physiology.

    价 格：￥电议型 号：T40680产 地：中国大陆

  • T39680DiflomotecanDiflomotecanBN 80915

    Diflomotecan (BN 80915) is a potent, orally active topoisomerase I inhibitor that displays enhanced plasma stability and superior preclinical anti-tumor activity relative to other established compounds.

    价 格：￥电议型 号：T39680产 地：中国大陆

  • T39044Rezvilutamide；瑞维鲁胺SHR3680；SHR3680

    Rezvilutamide (SHR3680) is an orally available androgen receptor inhibitor that crosses the blood-brain barrier and has antitumor activity.Rezvilutamide (SHR3680) is used in the study of metastatic desmoplasia-resistant prostate cancer.

    价 格：￥电议型 号：T39044产 地：中国大陆

  • T38680RJW100；化合物RJW100RJW100

    RJW100 is a compound that acts as a potent agonist of liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1), exhibiting pEC50 values of 6.6 and 7.5, respectively. Additionally, RJW100 induces robust activation of the miR-200c (miRNA-200c, microRNA-200c) promoter.

    价 格：￥电议型 号：T38680产 地：中国大陆

  • T376803-hydroxy Palmitic Acid methyl ester；3-hydroxy Palmitic Acid methyl ester3-hydroxy Palmitic Acid met

    3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum.

    价 格：￥电议型 号：T37680产 地：中国大陆

  • T37354CAY10680；CAY10680CAY10680；CAY10680

    CAY10680 is a dopamine-sparing, benzothiazinone compound that selectively inhibits both MAO-B activity (IC50 = 34.9 nM in human) and adenosine A2A receptors (Ki = 39.5 nM in human). It demonstrates significantly less potent inhibitory values for other adenosine receptor subtypes (Kis > 1 μM) and MAO-A (IC50 ≥ 10 μM). At 1-20 μM, CAY10680 has been shown to abolish cAMP accumulation in CHO cells transfected with adenosine A2A receptors. In the central nervous system adenosine A2A receptor expressi

    价 格：￥电议型 号：T37354产 地：中国大陆

  • T36809UoS 12258UoS 12258UoS 12258

    Positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro). Also potentiates AMPA-mediated synaptic responses in vivo. Improves performance of rats in various learning and memory paradigms

    价 格：￥电议型 号：T36809产 地：中国大陆

  • T36808UK 59811 hydrochloride；UK 59811 hydrochlorideUK 59811 hydrochloride

    Blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM).

    价 格：￥电议型 号：T36808产 地：中国大陆

  • T36807Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)；Estradiol 17-(β-D-Glucuronide) (sodium salt hyd

    Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2

    价 格：￥电议型 号：T36807产 地：中国大陆

  • T36806TPC2-A1-P；TPC2-A1-PTPC2-A1-P；TPC2-A1-P

    TPC2-A1-P is a potent, membrane-permeable agonist of the two-pore channel 2 (TPC2), exhibiting an EC50 of 10.5 μM. It exerts its effects by mimicking the physiological actions of PI(3,5)P2, and demonstrates greater efficacy in inducing Na2+ mobilization from TPC2 compared to TPC-A1-N. This compound serves as a valuable tool for probing various functions of TPC2 channels in intact cells[1][2][3].

    价 格：￥电议型 号：T36806产 地：中国大陆

  • T36805TPC2-A1-NTPC2-A1-NTPC2-A1-N

    TPC2-A1-N is a novel, lipophilic, membrane permeable isoform-selective small molecule agonist of two-pore channel 2 (TPC2). TPC2-A1-N plays its role by mimicking the physiological actions of NAADP and PI(3,5)P2 through independent binding sites. TPC2-A1-N has inverse effects on key lysosomal activities and increases the pH in the lysosomal lumen in a TPC2-dependent manner[1].

    价 格：￥电议型 号：T36805产 地：中国大陆

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