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T21154Chlorfluazuron;化合物 T21154IKI 7899|||AI3-29785|||CCRIS 2680|||CGA 112913|||Atabron;IKI 7899|||AI3-297
Chlorfluazuron, a chitin synthesis inhibitor, is commonly used as an insect growth regulator for controlling the major insect pests in crops.
价 格:¥电议型 号:T21154产 地:中国大陆
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T20802Flumethasone pivalate特戊酸氟米松Locacorten|||NSC-107680|||特戊酸氟米松|||Lorinden|||NSC 107680|||NSC107680|||Lo
Flumethasone pivalate (Locorten) has antipruritic, anti-inflammatory, and vasoconstrictive properties and can be used in studies about adrenocortical suppression, cutaneous atrophy, plasma transcortin binding, and telangiectasia.
价 格:¥电议型 号:T20802产 地:中国大陆
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T20080Exifone;依昔苯酮NSC 680919|||NSC680919|||NSC-680919;NSC 680919|||NSC680919|||NSC-680919|||依昔苯酮
Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increased relative maximal rate of HDAC1-catalyzed deacetylation.
价 格:¥电议型 号:T20080产 地:中国大陆
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T19680Zotepine;佐替平Zotepine
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second-generation antipsychotic with a primary use as a treatment for schizophrenia, although clinical trials have been conducted into its efficacy as an antimanic agent in patients with acute bipolar mania.
价 格:¥电议型 号:T19680产 地:中国大陆
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T19674Verlukast;化合物 T19674MK 0679|||MK-679|||L 668,019|||MK 679|||L 668019|||L-668,019;MK 0679|||MK-679|||
Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 = 10.7 +/- 1.6 nM) but is essentially inactive versus [3H]leukotriene C4 binding in guinea-pig lung homogenates (IC50: 19 and 33 microM).
价 格:¥电议型 号:T19674产 地:中国大陆
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T17731LCL2A-SN-38 DCA 1279680-68-0(free base);化合物CL2A-SN-38 DCACL2A-SN-38 DCA 1279680-68-0(free base)
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable t
价 格:¥电议型 号:T17731L产 地:中国大陆
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T17680Boc-NH-PEG4-Ms;化合物 T17680Boc-NH-PEG4-Ms
Boc-NH-PEG4-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17680产 地:中国大陆
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T16809Rupintrivir芦平曲韦AG-7088|||AG7088|||Rupintrivirvr
Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirvr inhibits the replication of EV71 and EV-D68, and may be useful for the study of viral infections.
价 格:¥电议型 号:T16809产 地:中国大陆
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T16808Runcaciguat;化合物RuncaciguatRuncaciguat
Runcaciguat is a soluble guanylate cyclase stimulator. Runcaciguat combines with selective partial adenosine A1 receptor agonists and can be used in studies about cardiovascular and renal diseases.
价 格:¥电议型 号:T16808产 地:中国大陆
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T16807Rucaparib monocamsylate;瑞卡帕布樟脑磺酸盐Rucaparib Camsylate;瑞卡帕布樟脑磺酸盐|||Rucaparib Camsylate
Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains.
价 格:¥电议型 号:T16807产 地:中国大陆
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T16805RTS-V5;化合物 T16805RTS-V5
RTS-V5 is a dual inhibitor of HDAC/proteasome (IC50s: 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively).
价 格:¥电议型 号:T16805产 地:中国大陆
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T16803RS 8359;化合物RS 8359RS 8359
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity.
价 格:¥电议型 号:T16803产 地:中国大陆
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T16802Lonapalene;氯萘帕林RS4317;RS4317
Lonapalene (RS4317) is a 5-lipoxygenase (5-LO) inhibitor with anti-psoriasis efficacy.Lonapalene topically blocks skin inflammation.
价 格:¥电议型 号:T16802产 地:中国大陆
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T16801(RS)-(Tetrazol-5-yl)glycine;化合物(RS)-(Tetrazol-5-yl)glycineLY 285265|||D,L-(tetrazol-5-yl)glycine;LY
(RS)-(Tetrazol-5-yl)glycine (LY 285265) (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D, and GluN1/GluN2A, respectively.
价 格:¥电议型 号:T16801产 地:中国大陆
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T16800(RS)-AMPA;化合物(RS)-AMPA(±)-AMPA;(±)-AMPA
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.
价 格:¥电议型 号:T16800产 地:中国大陆
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T1680Tolazoline hydrochloride;苯甲唑啉盐酸盐Imidaline hydrochloride|||Imidaline (hydrochloride)|||Benzidazol hyd
Tolazoline hydrochloride (NSC35110 (hydrochloride)) is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn.
价 格:¥电议型 号:T1680产 地:中国大陆
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T16680PTC-028;化合物PTC-028PTC-028
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
价 格:¥电议型 号:T16680产 地:中国大陆
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T15680L-159282;化合物 T15680MK 996;MK 996
L-159282 is an orally active and nonpeptide angiotensin II receptor antagonist. It also has anti-hypertensive activity.
价 格:¥电议型 号:T15680产 地:中国大陆
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T15472Hepsulfam;化合物 T15472NCI 329680|||ZINC01574758;NCI 329680|||ZINC01574758
Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).
价 格:¥电议型 号:T15472产 地:中国大陆
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T14680BMS-906024;化合物 BMS-906024Osugacestat|||AL-101|||BM-0018;Osugacestat|||AL-101|||BM-0018
BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-906024 prevents the activation of all four Notch receptors, and is active against Notch1, -2, -3 and -4 receptors. BMS-906024 prevents the activation of all four Notch receptors, with IC50s of 1.6, 0.7, 3.4 and 2.9 nM for Notch1, -2, -3 and -4 receptors, respectively.
价 格:¥电议型 号:T14680产 地:中国大陆