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T36803AAQ chloride；AAQ chlorideAAQ chloride
Photoswitchable Kv channel blocker (IC50 values are 2 and 64 μM at 500 nm and 380 nm respectively). Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Exhibits minimal activity at Nav1.2 and L-type Ca2+ channels. Stimulates action potential firing of hippocampal neurons in vitro at 500 nm and restores visual responsiveness in blind mice at 380 nm.
价 格：￥电议型 号：T36803产 地：中国大陆
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T36802LBisubstrate Inhibitor 78 HCl；Bisubstrate 抑制剂 78盐酸盐Bisubstrate Inhibitor 78 HCl(2368247-39-4 Free bas
Bisubstrate Inhibitor 78 HCl is an NNMT inhibitor (IC50 = 1.41 μM) with potential anticancer activity, inhibiting the proliferation of HSC-2 oral cancer cells at 100 μM.
价 格：￥电议型 号：T36802L产 地：中国大陆
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T36802Bisubstrate Inhibitor 78；Bisubstrate Inhibitor 78Bisubstrate Inhibitor 78
Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50= 1.41 μM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinamide . Bisubstrate inhibitor 78 is selective for NNMT over histone-lysine N-methytransferase NSD2 and protein arginine methyltransferase 1 (PRMT1; IC50s = >50 μM for both). It reduces levels of 1-methylnicotinamide in, and inhibits proliferation of, HSC-2 oral cancer cells when us
价 格：￥电议型 号：T36802产 地：中国大陆
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T36801Binucleine 2Binucleine 2Binucleine 2
Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division
价 格：￥电议型 号：T36801产 地：中国大陆
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T36800EN219；EN219EN219
EN219 is a synthetic recruiter of the E3 ubiquitin ligase RNF114.1It binds to cysteine 8 (C8) in the intrinsically disordered region of RNF114 (RNF114-C8; IC50= 470 nM) and inhibits RNF114-induced autoubiquitination and p21 ubiquitination in a cell-free assay when used at a concentration of 50 μM. EN219 (1 μM) also interacts with cysteine residues in the tubulin β1 chain (TUBB1), heat shock protein 60 (Hsp60), also known as Hsp family D member 1 (HspD1), and histone H3.1 (HIST1H3A) in 231MFP hum
价 格：￥电议型 号：T36800产 地：中国大陆
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T3680ISO-1；化合物ISO1MIF Antagonist|||ISO 1；MIF Antagonist|||ISO 1
ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages.
价 格：￥电议型 号：T3680产 地：中国大陆
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T36680SM1-71；化合物 SM1-71SM1-71
SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-71 can be used as a kinase probe with anticancer activity and inhibits the proliferation of various cancer cell lines.
价 格：￥电议型 号：T36680产 地：中国大陆
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T35916Simotinib；西莫替尼AL-6802|||SIM-6802；AL-6802|||SIM-6802
Simotinib (AL-6802) is a selective and orally bioactive EGFR tyrosine kinase inhibitor (IC50: 19.9 nM) with anti-tumour activity for the study of non-small cell lung cancer.
价 格：￥电议型 号：T35916产 地：中国大陆
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T356802-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide；2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbo
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteriaS. aureus,M. luteus, andB. cereus(MICs = 130, 100, and 50 μg/ml, respectively), and the fungiC. albicans,G. candidum,T. rubrum,F. oxysporum,A. flavus, andS. brevicaulis(MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a prec
价 格：￥电议型 号：T35680产 地：中国大陆
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T35133WIN-68056；化合物 T35133WIN 68056；WIN 68056
WIN-68056 is a wetting agent in x-ray contrast compositions.
价 格：￥电议型 号：T35133产 地：中国大陆
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T34766T-808；化合物 T34766AVI-680；AVI-680
T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer´s disease.
价 格：￥电议型 号：T34766产 地：中国大陆
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T34680Sodium stibocaptate；化合物 T34680Sodium stibocaptate
Sodium stibocaptate is a biochemical.
价 格：￥电议型 号：T34680产 地：中国大陆
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T33955PF-6808472；化合物 T33955OX-44|||OX44|||PF 6808472|||OX 44|||PF6808472；OX-44|||OX44|||PF 6808472|||OX 44
PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.
价 格：￥电议型 号：T33955产 地：中国大陆
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T33431MK-287；化合物 T33431L680573|||L 680573|||L-680573；L680573|||L 680573|||L-680573
MK-287 (L-680573) is a platelet activator (PAF) antagonist that effectively inhibates the binding of [3H]C18-PAF to human platelets, polynucleated white blood cells (PMN), and pulmonary membranes. May be used to treat asthma,
价 格：￥电议型 号：T33431产 地：中国大陆
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T33387Mimbane；化合物 T33387NSC-76808|||NSC76808|||NSC 76808；NSC-76808|||NSC76808|||NSC 76808
Mimbane is a biochemical.
价 格：￥电议型 号：T33387产 地：中国大陆
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T32680Leukotriene E-4 sulfone；化合物 T32680Leukotriene E-4 sulfone
Leukotriene E-4 sulfone is a synthetic leukotriene.
价 格：￥电议型 号：T32680产 地：中国大陆
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T32473L 698680；化合物 T32473L 698,680|||L698680|||L-698680|||L698,680|||L-698,680；L 698,680|||L698680|||L-698
L 698680 is a 6-hydroxy metabolite of L-696229.
价 格：￥电议型 号：T32473产 地：中国大陆
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T31592E6801；化合物E6801E 6801|||E-6801；E 6801|||E-6801
E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson´s disease, depression, obesity epilepsy, anxiety, and many other diseases.
价 格：￥电议型 号：T31592产 地：中国大陆
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T30914CI 680；化合物 T30914CI680|||UNII-0X76UOC3KR|||CI-680；CI680|||UNII-0X76UOC3KR|||CI-680
CI 680 is a bio-active chemical.
价 格：￥电议型 号：T30914产 地：中国大陆
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T30842Cgp 6809；化合物 T30842Cgp6809|||Cgp-6809；Cgp6809|||Cgp-6809
Cgp 6809 is a new methylnitrosoureido-sugar derivative that has been shown to be active against a broad spectrum of transplantable tumours in mice and rats. CGP 6809 is a promising new agent for clinical trials, especially for large bowel and epidermoid lung cancer.
价 格：￥电议型 号：T30842产 地：中国大陆
