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T73224AMPK-IN-1;化合物 AMPK-IN-1AMPK-IN-1
AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM. It induces phosphorylation of eEF2 independent of the mTORC1 pathway.
价 格:¥电议型 号:T73224产 地:中国大陆
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T73059Acamprosate;化合物 AcamprosateAcamprosate
Acamprosate, an orally active prototypic neuromodulator, is utilized in the study and treatment of alcohol dependence and alcoholism.
价 格:¥电议型 号:T73059产 地:中国大陆
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T72690AMPK activator 9;化合物 AMPK activator 9AMPK activator 9
AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 ?M, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its potential application in understanding and possibly treating this condition.
价 格:¥电议型 号:T72690产 地:中国大陆
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T72635AMPD2 inhibitor 2;化合物 AMPD2 inhibitor 2AMPD2 inhibitor 2
AMPD2 Inhibitor 2 is a potent inhibitor of AMP deaminase 2 (AMPD2), demonstrating inhibitory concentration 50 (IC50) values of 0.1 μM for human AMPD2 (hAMPD2) and 0.28 μM for mouse AMPD2 (mAMPD2). This compound is valuable for research into the physiological roles of AMPD2, especially in mice on a high-fat diet.
价 格:¥电议型 号:T72635产 地:中国大陆
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T72623Nampt activator-3;化合物 Nampt activator-3Nampt activator-3
NAMPT Activator-3, a derivative of NAT, is a potent activator of NAMPT, demonstrating an EC50 of 2.6 μM and KD of 132 nM. It effectively shields cultured cells against toxicity induced by FK866 and has demonstrated significant neuroprotective effects in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model, without any apparent toxicity [1].
价 格:¥电议型 号:T72623产 地:中国大陆
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T72617Nampt activator-2;Nampt激活剂2Nampt activator-2
Nampt activator-2 is a NAMPT activator (EC50: 0.023 μM). Nampt activator-2 has an affinity for CYP2C9, 2D6, and 2C19 with affinity values of 0.060 μM, 0.41 μM, and 0.59 μM, respectively.Nampt activator-2 can be used in the study of atherosclerosis, obesity, type II diabetes, insulin resistance, and type I diabetes.
价 格:¥电议型 号:T72617产 地:中国大陆
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T72093Thiamphenicol glycinate hydrochloride化合物 Thiamphenicol glycinate hydrochloride甲砜霉素甘氨酸酯盐酸盐
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent utilized in research on respiratory tract infections.
价 格:¥电议型 号:T72093产 地:中国大陆
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T71810Thiamphenicol palmitate;化合物 Thiamphenicol palmitateThiamphenicol palmitate
Thiamphenicol palmitate is a Prodrug of Thiamphenicol, inhibiting the 50S subunit of the bacterial ribosome and protein translation.
价 格:¥电议型 号:T71810产 地:中国大陆
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T71538AMPCP;化合物 AMPCPAMPCP
AMPCP is an Ecto-5´-nucleotidase (CD73) inhibitor.
价 格:¥电议型 号:T71538产 地:中国大陆
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T71443Amphidinolide D;化合物 Amphidinolide DAmphidinolide D
Amphidinolide D is a powerful activator of actomyosin ATPase enhances skeletal muscle contraction.
价 格:¥电议型 号:T71443产 地:中国大陆
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T70961Dmb-rifampicin;化合物 Dmb-rifampicinDmb-rifampicin
Dmb-rifampicin is an inhibitor of nucleic acid polymerases.
价 格:¥电议型 号:T70961产 地:中国大陆
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T70862AMPK Activator SC4;化合物 AMPK Activator SC4AMPK Activator SC4
SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.
价 格:¥电议型 号:T70862产 地:中国大陆
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T69856Pralurbactam;化合物 PralurbactamPralurbactam
Pralurbactam is a β-Lactamase inhibitor utilized in the research of bacterial infections.
价 格:¥电议型 号:T69856产 地:中国大陆
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T69821AMP423;化合物 AMP423AMP423
AMP423 is a naphthyl derivative of 2-cyanoaziridine-1-carboxamide with structural similarity to the pro-oxidant anti-tumor agent imexon. AMP423 was active in SCID mice bearing 8226/S myeloma and SU-DHL-6 B-cell lymphoma tumors, with a median tumor growth delay (T-C) of 21 days (P = 0.0002) and 5 days (P = 0.004), respectively, and a median tumor growth inhibition (T/C) of 33.3% (P = 0.03) and 82% (P = 0.01), respectively. In non-tumor-bearing mice, AMP423 was not myelosuppressive.
价 格:¥电议型 号:T69821产 地:中国大陆
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T69713Fosamprenavir sodium;化合物 Fosamprenavir sodiumFosamprenavir sodium
Fosamprenavir sodium is an HIV protease inhibitor that is the water soluble prodrug of amprenavir.
价 格:¥电议型 号:T69713产 地:中国大陆
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T69074Premazepam;化合物 PremazepamPremazepam
Premazepam is a benzodiazepine derivative. It is a partial agonist of benzodiazepine receptors and was shown in 1984 to possess both anxiolytic and sedative properties in humans but was never marketed.
价 格:¥电议型 号:T69074产 地:中国大陆
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T67972LAmp579 TFA;Amp579三氟乙酸盐Amp579 TFA(213453-89-5 Free base);Amp579 TFA(213453-89-5 Free base)
Amp579 TFA is a novel adenosine A1/A2a receptor agonist that induces acute and delayed preconditioning against myocardial shock in vivo.
价 格:¥电议型 号:T67972L产 地:中国大陆
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T67937Ampreloxetine hydrochloride;阿普罗西汀盐酸盐TD-9855 HCl;TD-9855 HCl
Ampreloxetine hydrochloride (TD-9855 HCl) has anti-inflammatory activity and is a potential compound for the treatment of depression and Alzheimer´s disease.
价 格:¥电议型 号:T67937产 地:中国大陆
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T67925Nampt activator-1;化合物Nampt activator-1Nampt activator-1
NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 μM). NAMPT activator-1 effectively protects cultured cells from FK866-mediated toxicity and is a potential neuroprotective compound.
价 格:¥电议型 号:T67925产 地:中国大陆
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T67810Tampramine;坦帕明Tampramine
Tampramine is a selective norepinephrine reuptake inhibitor that shows a low affinity for adrenergic, histaminergic and muscarinic receptors. Tampramine is a candidate compound for the treatment of forced swimming test (FST) depression.
价 格:¥电议型 号:T67810产 地:中国大陆