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T80147EcAMP3;化合物 EcAMP3EcAMP3
EcAMP3, a hairpin-like peptide, exhibits both antifungal and antibacterial properties. It belongs to the EcAMP precursor family characterized by seven identical cysteine motifs: C1XXXC2(11–13)C3XXXC4 [1].
价 格:¥电议型 号:T80147产 地:中国大陆
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T80139CRAMP-18 (mouse);化合物 CRAMP-18 (mouse)CRAMP-18 (mouse)
CRAMP-18 (mouse) is an antibiotic peptide with demonstrated efficacy against Gram-negative bacteria, including S. typhimurium and P. aeruginosa, while exhibiting no hemolytic activity. This compound shows promise for research into antifungal, antibacterial, and antitumor applications [1] [2].
价 格:¥电议型 号:T80139产 地:中国大陆
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T80123CRAMP (mouse);化合物 CRAMP (mouse)CRAMP (mouse)
CRAMP (mouse), an antimicrobial peptide, is utilized in the study of biofilm-associated infections [1].
价 格:¥电议型 号:T80123产 地:中国大陆
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T80080PAMP-12 (unmodified) (TFA);化合物 PAMP-12 (unmodified) (TFA)PAMP-12 (unmodified) (TFA)
PAMP-12 (unmodified) TFA, an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells [1].
价 格:¥电议型 号:T80080产 地:中国大陆
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T798839-Chloromethyl-10-hydroxy-11-F-Camptothecin;化合物 9-Chloromethyl-10-hydroxy-11-F-Camptothecin9-Chlorom
9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential applications in anticancer research [1].
价 格:¥电议型 号:T79883产 地:中国大陆
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T79649CB1R/AMPK modulator 1;化合物 CB1R/AMPK modulator 1CB1R/AMPK modulator 1
Compound 38-S is an orally active CB1R/AMPK modulator with a K i of 0.81 nM and an IC50 of 3.9 nM for CB1R. This compound activates AMPK and has been shown to decrease food intake and body weight, in addition to enhancing glucose tolerance and insulin sensitivity [1].
价 格:¥电议型 号:T79649产 地:中国大陆
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T7959(+)-ISOPINOCAMPHEOL;(1S,2S,3S,5R)-(+)-异松蒎醇(+)-ISOPINOCAMPHEOL
(+)-ISOPINOCAMPHEOL is a natural product.
价 格:¥电议型 号:T7959产 地:中国大陆
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T79504AMPA receptor modulator-6;化合物 AMPA receptor modulator-6AMPA receptor modulator-6
AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].
价 格:¥电议型 号:T79504产 地:中国大陆
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T79437NAMPT degrader-3;化合物 NAMPT degrader-3NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism. It exhibits cytotoxic properties and inhibits the proliferation of A2780 cells [1].
价 格:¥电议型 号:T79437产 地:中国大陆
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T79226AMPK activator 11;化合物 AMPK activator 11AMPK activator 11
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative phosphorylation (OXPHOS) (mitochondrial metabolism). This compound demonstrates particular efficacy in inhibiting RKO xenograft growth, rendering it useful for anti-tumor and metabolic disease research [1].
价 格:¥电议型 号:T79226产 地:中国大陆
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T79191AMPA receptor modulator-5;化合物 AMPA receptor modulator-5AMPA receptor modulator-5
AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].
价 格:¥电议型 号:T79191产 地:中国大陆
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T78971AMPA receptor modulator-4;化合物 AMPA receptor modulator-4AMPA receptor modulator-4
AMPA Receptor Modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), serves as an orally active positive allosteric modulator of the AMPA receptors (AMPAR PAMs). This compound is capable of crossing the blood-brain barrier and has been found to enhance cognitive performance and working memory in mice [1].
价 格:¥电议型 号:T78971产 地:中国大陆
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T78791AMPK activator 12;AMPK 激活剂12AMPK activator 12
AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein in human hepatocytes, which can be used for cancer research.
价 格:¥电议型 号:T78791产 地:中国大陆
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T78027PAMP-12 (unmodified);化合物 PAMP-12 (unmodified)PAMP-12 (unmodified)
PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from sympathetic nerve endings and adrenal chromaffin cells [1].
价 格:¥电议型 号:T78027产 地:中国大陆
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T77870Mal-Val-Ala-PABA-cGAMP;化合物 Mal-Val-Ala-PABA-cGAMPMal-Val-Ala-PABA-cGAMP
Mal-Val-Ala-PABA-cGAMP serves as an ADC linker for attachment to STING agonists and is utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T77870产 地:中国大陆
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T778207-Aminomethyl-10-methyl-11-fluoro camptothecin;化合物 7-Aminomethyl-10-methyl-11-fluoro camptothecin7-A
7-Aminomethyl-10-methyl-11-fluoro camptothecin, serving as a cytotoxic component of the antibody-drug conjugate (ADC) MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin, is employed in the synthesis of camptothecin ADCs [1].
价 格:¥电议型 号:T77820产 地:中国大陆
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T77701FL118;化合物FL118FL 118|||FL-118|||10,11-(Methylenedioxy)-20(S)-camptothecin;FL 118|||FL-118|||10,11-(M
FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway, thereby inhibiting migration and invasion of human breast cancer cells.
价 格:¥电议型 号:T77701产 地:中国大陆
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T76951Zampilimab;化合物 ZampilimabZampilimab
Zampilimab (UCB-7858), a monoclonal antibody targeting transglutaminase 2 (TG2), exhibits potential applications in renal transplantation [1] [2].
价 格:¥电议型 号:T76951产 地:中国大陆
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T76814Lampalizumab;化合物 LampalizumabLampalizumab
Lampalizumab (RG 7417), a humanized monoclonal antibody, selectively inhibits complement Factor D in the alternative complement pathway by binding to an exosite and sterically hindering Factor B´s access to the active site. It is employed in the study of age-related macular degeneration (AMD) [1] [2].
价 格:¥电议型 号:T76814产 地:中国大陆
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T76352Lamprey LH-RH I;化合物 Lamprey LH-RH ILamprey LH-RH I
Lamprey LH-RH I, a gonadotropin-releasing hormone, effectively increases plasma steroid levels and induces ovulation in lampreys, yet demonstrates no biological activity in other animal models [1].
价 格:¥电议型 号:T76352产 地:中国大陆