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T40002Pomalidomide-C3-NH2 hydrochloride;化合物Pomalidomide-C3-NH2 hydrochloridePomalidomide-C3-NH2 hydrochlor
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40002产 地:中国大陆
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T40000Pomalidomide-C3-I;化合物Pomalidomide-C3-IPomalidomide-C3-I
Pomalidomide-C3-I is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40000产 地:中国大陆
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T39894Thalidomide-4-C3-NH2 hydrochloride;Thalidomide-4-C3-NH2 hydrochlorideThalidomide-4-C3-NH2 hydrochlor
Thalidomide-4-C3-NH2 hydrochloride is a Thalidomide-derived cereblon ligand utilized for the recruitment of CRBN protein. This compound can be linked to the ligand for protein using a linker to create PROTACs.
价 格:¥电议型 号:T39894产 地:中国大陆
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T39637Pomalidomide-amido-C3-COOH;Pomalidomide-amido-C3-COOHPomalidomide-amido-C3-COOH;Pomalidomide-amido-C
Pomalidomide-amido-C3-COOH is a conjugate compound synthesized as an E3 ligase ligand-linker. It combines a cereblon ligand derived from Pomalidomide with a linker, both of which are used in PROTAC technology.
价 格:¥电议型 号:T39637产 地:中国大陆
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T39426Thalidomide-O-amido-C3-NH2;Thalidomide-O-amido-C3-NH2Thalidomide-O-amido-C3-NH2|||Cereblon Ligand-L
Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate, which combines the cereblon ligand derived from Thalidomide with a linker utilized in PROTAC technology.
价 格:¥电议型 号:T39426产 地:中国大陆
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T39424Cyanuric acid-13C3;Cyanuric acid-13C3Cyanuric acid-13C3;Cyanuric acid-13C3
Cyanuric acid-13C3 is 13C labeled Cyanuric acid.
价 格:¥电议型 号:T39424产 地:中国大陆
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T39360N-Boc-C1-PEG3-C3-NH2;N-Boc-C1-PEG3-C3-NH2N-Boc-C1-PEG3-C3-NH2;N-Boc-C1-PEG3-C3-NH2
N-Boc-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39360产 地:中国大陆
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T39215Thalidomide-O-amido-C3-PEG3-C1-NH2;Thalidomide-O-amido-C3-PEG3-C1-NH2Thalidomide-O-amido-C3-PEG3-C1-
Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized conjugate compound that serves as an E3 ligase ligand-linker. It features a cereblon ligand based on Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology.
价 格:¥电议型 号:T39215产 地:中国大陆
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T39112Propargyl-PEG2-urea-C3-triethoxysilane;Propargyl-PEG2-urea-C3-triethoxysilanePropargyl-PEG2-urea-C3-
Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker utilized for PROTAC synthesis.
价 格:¥电议型 号:T39112产 地:中国大陆
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T3878Raddeanin A;竹节香附素ANSC382873|||Anemodeanin A|||Raddeanin R3;NSC382873|||竹节香附素A|||Anemodeanin A|||Radd
Raddeanin A (NSC-382873) has moderate inhibitory activity against histone deacetylases (HDACs). Raddeanin A has high antiangiogenic potency, antitumor activity.
价 格:¥电议型 号:T3878产 地:中国大陆
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T38713Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH;Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OHFmoc-Asn(Ac3AcNH-beta-Glc)-OH|||F
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH, also known as Fmoc-Asn(Ac3AcNH-beta-Glc)-OH, is a chemical compound used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, which serve as tumor imaging agents, are valuable tools for positron emission tomography (PET) research.
价 格:¥电议型 号:T38713产 地:中国大陆
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T38684AKR1C3-IN-4;化合物AKR1C3-IN-4AKR1C3-IN-4;AKR1C3-IN-4
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
价 格:¥电议型 号:T38684产 地:中国大陆
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T38591Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA);Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)Biotinyl-NH-PEG3-
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, utilized for synthesizing PROTACs.
价 格:¥电议型 号:T38591产 地:中国大陆
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T38549Azido-C1-PEG3-C3-NH2;Azido-C1-PEG3-C3-NH2Azido-C1-PEG3-C3-NH2;Azido-C1-PEG3-C3-NH2
Azido-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T38549产 地:中国大陆
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T38547TLR4-IN-C34-C2-COOH;TLR4-IN-C34-C2-COOHTLR4-IN-C34-C2-COOH;TLR4-IN-C34-C2-COOH
TLR4-IN-C34-C2-COO is a linker compound that incorporates TLR4 inhibitor TLR4-IN-C34. It effectively inhibits TLR4 activity in enterocytes and macrophages. Moreover, it demonstrates a notable ability to mitigate systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis.
价 格:¥电议型 号:T38547产 地:中国大陆
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T38316ABC34;ABC34ABC34
ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). ABC34 demonstrates an IC50 value greater than 25 μM for the inhibition of 9-PAHSA but is more potent in blocking the serine hydrolase ABHD6 and the palmitoyl-protein hydrolase PPT1, which are both off-targets of JJH260.
价 格:¥电议型 号:T38316产 地:中国大陆
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T38287C3a Receptor Agonist;C3a受体激动剂C3a receptor agonist 1|||Complement 3a Receptor Agonist;C3a receptor ag
C3a Receptor Agonist (C3a receptor agonist 1) binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestinal ischemia-reperfusion injury. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. C3a stimulates differentiation of neural progenitor cells in vitro.
价 格:¥电议型 号:T38287产 地:中国大陆
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T38037Caffeic Acid-13C3;Caffeic Acid-13C3Caffeic Acid-13C3;Caffeic Acid-13C3
Caffeic acid-13C3 is an isotopically enriched form of caffeic acid that is intended for use as an internal standard for the quantification of caffeic acid by GC- or LC-MS. Caffeic acid is an inhibitor of 5-LO , with IC50 values of 3.7-72 μM, and 12-LO, with IC50 values of 5.1-30 μM.
价 格:¥电议型 号:T38037产 地:中国大陆
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T371191,2,3-Trioctanoyl-rac-glycerol-13C3;1,2,3-Trioctanoyl-rac-glycerol-13C31,2,3-Trioctanoyl-rac-glycero
1,2,3-Trioctanoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2,3-trioctanoyl-rac-glycerol by GC- or LC-MS. 1,2,3-Trioctanoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trioctanoyl-rac-glycerol increases hippocampal levels of the glycolytic metabolites glucose 6-phosphate, fructose 6-phosphate, and β-hydroxybutyrate and the seizure threshold in the 6 Hz psychomo
价 格:¥电议型 号:T37119产 地:中国大陆
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T370441,2-Dioleoyl-rac-glycerol-13C3;1,2-Dioleoyl-rac-glycerol-13C31,2-Dioleoyl-rac-glycerol-13C3;1,2-Diol
1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3
价 格:¥电议型 号:T37044产 地:中国大陆