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T7497LC3a 70-77 2TFA(63555-63-5(free base));化合物C3a 70-77 2TFAComplement 3a (70-77);Complement 3a (70-77)
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a.
价 格:¥电议型 号:T7497L产 地:中国大陆
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T7497C3a (70-77);化合物C3a 70-77Complement 3a (70-77)|||C3a 70-77;Complement 3a (70-77)|||C3a 70-77
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.
价 格:¥电议型 号:T7497产 地:中国大陆
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T74700Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine;化合物 Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylam
Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine is an immune stimulator antibody conjugate (ISAC) that consists of an anti-human epidermal growth factor receptor 2 (HER2) antibody, a STING agonist (ADU-S100), and a linker, utilized in cancer research.
价 格:¥电议型 号:T74700产 地:中国大陆
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T74554Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH;化合物 Tazemetostat de(methylene morpholine)-O-C3-O
Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH (Compound 21b), an EZH2 degrader, is employed in lymphoma research [1].
价 格:¥电议型 号:T74554产 地:中国大陆
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T74485STC314;化合物 STC314STC314
STC314 is an anti-infective agent that reverses organ damage caused by excessive immune response by neutralizing extracellular histones and neutrophil trapping networks, and can be used in the study of sepsis and acute respiratory distress syndrome (ARDS).STC314 protects the stability of lipid bilayers, and inhibits platelet activation and erythrocyte damage.STC314 is also used in the study of prostate cancer.Nardeterol HCl is a selective kappa agonist with analgesic activity.
价 格:¥电议型 号:T74485产 地:中国大陆
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T74462SNIPER(TACC3)-11;化合物 SNIPER(TACC3)-11SNIPER(TACC3)-11
SNIPER(TACC3)-11 is a potent degrader of the FGFR3-TACC3 protein, effectively diminishing its levels and inhibiting the proliferation of cancer cells positive for FGFR3-TACC3 [1].
价 格:¥电议型 号:T74462产 地:中国大陆
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T74389Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH;化合物 Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-am
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH, a chemical compound, serves as a linker incorporating TLR4 inhibitor TLR4-IN-C34. This compound effectively inhibits TLR4 in both enterocytes and macrophages, significantly reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74389产 地:中国大陆
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T74388Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;化合物 Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOHTri
Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH is a chemical linker incorporating the TLR4 inhibitor, TLR4-IN-C34, which suppresses TLR4 activity in enterocytes and macrophages, consequently diminishing systemic inflammation observed in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74388产 地:中国大陆
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T74387Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH;化合物 Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOHTri(TLR
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a chemical linker featuring the TLR4 inhibitor TLR4-IN-C34, known for inhibition of TLR4 in enterocytes and macrophages, thereby diminishing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74387产 地:中国大陆
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T74383TLR4-IN-C34-C2-amide-C6-OH;化合物 TLR4-IN-C34-C2-amide-C6-OHTLR4-IN-C34-C2-amide-C6-OH
TLR4-IN-C34-C2-amide-C6-OH, a chemical compound, serves as a linker encompassing the TLR4 inhibitor TLR4-IN-C34. This inhibitor is known to target TLR4 in enterocytes and macrophages, effectively reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74383产 地:中国大陆
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T74379DLin-K-C3-DMA;化合物 DLin-K-C3-DMADLin-K-C3-DMA
DLin-K-C3-DMA, a cationic lipid, facilitates the synthesis of nucleic acid-lipid particles for nucleic acid delivery [1].
价 格:¥电议型 号:T74379产 地:中国大陆
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T7406AKR1C3-IN-13-(3,4-二氢-1H-异喹啉-2-磺酰基)-苯甲酸3-(3,4-二氢-1H-异喹啉-2-磺酰基)-苯甲酸
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
价 格:¥电议型 号:T7406产 地:中国大陆
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T74003HDAC3/6-IN-2;化合物 HDAC3/6-IN-2HDAC3/6-IN-2
HDAC3/6-IN-2 (compound 15) is a dual inhibitor targeting HDAC6 and HDAC3, exhibiting potent activity with IC50 values of 0.368 μM for HDAC6 and 0.635 μM for HDAC3. This compound demonstrates antitumor effects by inducing apoptosis in cancer cells and reducing HDAC6 and HDAC3 levels. This action is linked to the increased acetylation of H3 and α-tubulin [1].
价 格:¥电议型 号:T74003产 地:中国大陆
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T73356Ac32Az19;化合物 Ac32Az19Ac32Az19
Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressed HEK293/R2 cells.
价 格:¥电议型 号:T73356产 地:中国大陆
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T7293EC330;化合物EC330EC330
EC330, a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range.
价 格:¥电议型 号:T7293产 地:中国大陆
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T72910APOBEC3G-IN-1;APOBEC3G 抑制剂1APOBEC3G-IN-1
APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer.
价 格:¥电议型 号:T72910产 地:中国大陆
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T72631TACC3 inhibitor 1;化合物 TACC3 inhibitor 1TACC3 inhibitor 1
TACC3 inhibitor 1 is a potent TACC3 inhibitor that can cross the blood-brain barrier, inducing apoptosis and cell cycle arrest at the G2/M phase, as well as the generation of intracellular ROS (reactive oxygen species). It exhibits antiproliferative and anti-tumor activity.
价 格:¥电议型 号:T72631产 地:中国大陆
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T72019ZINC32540717;化合物 ZINC32540717ZINC32540717
ZINC32540717 is a potent ebolavirus (EBOV) inhibitor.
价 格:¥电议型 号:T72019产 地:中国大陆
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T71955C3001a;化合物 C3001aC3001a
C3001a is a selective activator for TREK, against other two-pore domain K+(K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a targets TREK channels in the peripheral nervous system to reduce the excitability of nociceptive neurons. In neuropathic pain, C3001a alleviated spontaneous pain and cold hyperalgesia. In a mouse model of acute pancreatitis, C3001a alleviated mechanical allodynia and inflammation. C3001a represents a lead compound which could a
价 格:¥电议型 号:T71955产 地:中国大陆
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T69490NSC368262;化合物 NSC368262NSC368262
NSC368262 is a selective Stat3-family member inhibitor. NSC368262 alkylates Cys468 in Stat3.
价 格:¥电议型 号:T69490产 地:中国大陆