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产品数:86101
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T36086CAY10567CAY10567CAY-10567|||CAY10567
CAY10567 has a wide range of applications in life science related research.
价 格:¥电议型 号:T36086产 地:中国大陆
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T36035CAY10784CAY10784CAY10784|||CAY-10784
CAY10784 is a STAT3 inhibitor (IC50= 0.74 μM in a reporter assay) and a derivative of WP1066 .1It inhibits proliferation of HeLa, Caco-2, A549, A375, U87MG, and HL-60 cancer cells (IC50s = 1.8, 1.8, 3, 2.8, 2.3, and 1.2 μM, respectively) but not PC3 or HT-29 cancer cells (IC50s = >10 μM for both). CAY10784 is also active againstH. pyloriandC. jejuni(MICs = 1.6 and 4.7 μM, respectively).2
价 格:¥电议型 号:T36035产 地:中国大陆
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T35986CAY10512CAY10512CAY10512|||CAY-10512
The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activatio
价 格:¥电议型 号:T35986产 地:中国大陆
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T35985CAY10487CAY10487CAY-10487|||CAY10487
The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity. The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits.
价 格:¥电议型 号:T35985产 地:中国大陆
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T35822CAY10722CAY10722CAY-10722|||CAY10722
CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 μM). SIRT3 is involved in modulating metabolic homeostasis as a NAD+-dependent protein deacetylase in the mitochondria. SIRT3 functions as either an oncogene or tumor suppressor, depending on cancer cell type. High SIRT3 expression in patient-derived esophageal cancer tissues is associated with shorter survival and, in mice, downregulation leads to a lower tumor load. In contrast, low SIRT3 expression in patie
价 格:¥电议型 号:T35822产 地:中国大陆
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T35820CAY10685CAY10685CAY10685|||CAY-10685
CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions. Its ability to inhibit N-acetyltransferase 10 activity has been used to modulate chromatin organization in order to study changes in nuclear architecture associated with cancer and certain laminopathies.
价 格:¥电议型 号:T35820产 地:中国大陆
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T35819CAY10677CAY10677CAY10677|||CAY-10677
CAY10677 has a wide range of applications in life science related research.
价 格:¥电议型 号:T35819产 地:中国大陆
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T35813CAY10592CAY10592CAY-10592|||CAY 10592|||CAY10592
Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharmacologies of PPARδ receptor agonists, though relatively obscure, have recently been reported to elevate high-density lipoprotein (HDL) cholesterol and lower plasma triglyceride (TG) levels in obese insulin resistant rhesus monkeys. CAY10592 is a full PPARδ agonist (EC50 = 30 nM)
价 格:¥电议型 号:T35813产 地:中国大陆
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T35221Y 18598;化合物 T35221Y-18598|||Y18598;Y-18598|||Y18598
Y 18598 is a biochemical.
价 格:¥电议型 号:T35221产 地:中国大陆
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T35220Y 14556;化合物 T35220Y14556|||Y-14556;Y14556|||Y-14556
Y 14556 is a biochemical.
价 格:¥电议型 号:T35220产 地:中国大陆
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T35219Y 12896;化合物 T35219Y12896|||Alanylbactobolin|||Y-12896;Y12896|||Alanylbactobolin|||Y-12896
Y 12896 has a wide range of applications in life science related research.
价 格:¥电议型 号:T35219产 地:中国大陆
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T35114WAY-123398 free base;化合物 T35114Way-123398|||Way 123398|||Way 123,398|||Way123398|||Way-123,398|||Way
Way 123398 is a class III antiarrhythmic agent.
价 格:¥电议型 号:T35114产 地:中国大陆
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T35113WAY 150138;化合物 T35113WAY150138|||WAY-150138;WAY150138|||WAY-150138
WAY 150138 inhibits the herpes simplex virus.
价 格:¥电议型 号:T35113产 地:中国大陆
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T35112WAY 126299A;化合物 T35112WAY126299A|||WAY-126299A;WAY126299A|||WAY-126299A
Way 126299a is a dual-acting 5-lipoxygenase inhibitor and leukotriene D4 antagonist.
价 格:¥电议型 号:T35112产 地:中国大陆
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T35111Way 125971;化合物 T35111Way-125971|||Way125971;Way-125971|||Way125971
Way 125971 is a bioactive chemcial.
价 格:¥电议型 号:T35111产 地:中国大陆
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T35110Way 123783;化合物 T35110Way-123783|||Way123783;Way-123783|||Way123783
Way 123783 is a bioactive chemical.
价 格:¥电议型 号:T35110产 地:中国大陆
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T35109Way 123223;化合物 T35109Way123223|||Way-123223;Way123223|||Way-123223
Way 123223 is a bioactive chemical.
价 格:¥电议型 号:T35109产 地:中国大陆
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T35108Way 120744;化合物 T35108Way120744|||Way-120744;Way120744|||Way-120744
Way 120744 is a new naphthyl 3h -1,2,3,5-oxadiazole 2-oxide.
价 格:¥电议型 号:T35108产 地:中国大陆
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T35107Way 120491;化合物 T35107Way120491|||Way-120,491|||Way-120491|||Celikalim;Way120491|||Way-120,491|||Way-
Way 120491 activates ATP-sensitive potassium channels.
价 格:¥电议型 号:T35107产 地:中国大陆
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T35106Way 100289;化合物 T35106Way-100289|||Way100289;Way-100289|||Way100289
Way 100289 is a selective 5-HT3 receptor antagonist.
价 格:¥电议型 号:T35106产 地:中国大陆