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T6419BMS-536924;胰岛素样生长因子-1 受体拮抗剂HY-10262|||BMS 536924|||CS-0117;HY-10262|||胰岛素样生长因子-1 受体拮抗剂|||BMS 536924|
BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
价 格:¥电议型 号:T6419产 地:中国大陆
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T63038WAY-181187 oxalate;化合物 WAY-181187 oxalateWAY-181187 oxalate
WAY-181187 (SAX-187) oxalate is a selective and potent agonist of the 5-HT6 receptor (Ki: 2.2 nM; EC50: 6.6 nM). wAY-181187 oxalate is a specific agonist that mediates 5-HT6 receptor-dependent signalling pathways (e.g. cAMP, Fyn and ERK1/2 kinases).
价 格:¥电议型 号:T63038产 地:中国大陆
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T6283Wortmannin;渥曼青霉素SL-2052|||KY-12420;SL-2052|||渥曼青霉素|||KY-12420
Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.
价 格:¥电议型 号:T6283产 地:中国大陆
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T6218Selumetinib;司美替尼ARRY-142886|||AZD6244;ARRY-142886|||司美替尼|||AZD6244
Selumetinib (AZD6244) (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).
价 格:¥电议型 号:T6218产 地:中国大陆
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T6179Moxalactam sodium salt拉氧头孢钠Latamoxef sodium|||6059 S|||拉氧头孢钠|||Moxalactam Disodium|||LY-127935|||Ant
Moxalactam sodium salt (LY-127935) is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.
价 格:¥电议型 号:T6179产 地:中国大陆
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T60065WAY-118959-A;化合物WAY-118959-AWAY-118959-A
WAY-118959-A is a potential microtubule acetylation inhibitor.
价 格:¥电议型 号:T60065产 地:中国大陆
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T60053Hamaline;化合物Hamaline9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole;9-(4-ch
Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.
价 格:¥电议型 号:T60053产 地:中国大陆
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T5825Iadademstat dihydrochloride;化合物ORY-1001(trans)ORY-1001(trans);ORY-1001(trans)
Iadademstat dihydrochloride (ORY-1001(trans)) , a Potent and Selective Covalent KDM1A/LSD1 Inhibitor, for the Treatment of Acute Leukemia.
价 格:¥电议型 号:T5825产 地:中国大陆
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T56625-Hydroxy-1-tetralone;5-羟基-1-四氢萘酮5-Hydroxy-1-tetralone
5-hydroxy-1-tetralone as the fluorescent labeling reagent.
价 格:¥电议型 号:T5662产 地:中国大陆
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T47481,4-Dioxane-2,5-diol;乙醇醛二聚体Glycolaldehyde dimer|||Hydroxyacetaldehyde dimer|||2,5-Dihydroxy-1,4-diox
1,4-Dioxane-2,5-diol (Glycolaldehyde dimer) is derivative of glycolaldehyde, which is the precursor molecule of various significant compounds including amino acid glycine and in the formose reaction.
价 格:¥电议型 号:T4748产 地:中国大陆
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T408377-Acetoxy-1-methylquinolinium iodide;7-乙酰氧基-1-甲基喹啉溴化物AMQI;7-乙酰氧基-1-甲基喹啉溴化物|||AMQI
7-Acetoxy-1-methylquinolinium iodide (AMQI) serves as a fluorogenic substrate for cholinesterase, with excitation (Ex) occurring at 320 nm and emission (Em) at 410 nm. In the fluorometric flow system, the hydrolysis of this compound is employed for the detection and identification of inhibitors.
价 格:¥电议型 号:T40837产 地:中国大陆
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T40351MHY-1685;5-(4-羟基亚苄基)巴比妥酸MHY-1685
MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can rejuvenate senile hCSCs by modulating autophagy.
价 格:¥电议型 号:T40351产 地:中国大陆
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T4010Juglone;5-羟基对萘醌5-Hydroxy-1,4-naphthoquinone|||Regianin;5-羟基对萘醌|||5-Hydroxy-1,4-naphthoquinone|||胡桃酮|
Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent
价 格:¥电议型 号:T4010产 地:中国大陆
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T39386(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid;(3β,7β,12β,20Z)-3,7,1
(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoid, demonstrates significant inhibitory effects on nitric oxide (NO) production in BV-2 microglia cells induced by n LPS, with an IC50 value of 9.55 uM. Moreover, this compound possesses anti-inflammatory properties.
价 格:¥电议型 号:T39386产 地:中国大陆
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T38975WAY-100135 dihydrochloride;WAY-100135 dihydrochlorideWAY-100135 dihydrochloride
WAY-100135 dihydrochloride is a potent and selective antagonist of both presynaptic and postsynaptic 5-HT 1A receptors, exhibiting an IC 50 value of 34 nM specifically at the rat hippocampal 5-HT 1A receptor. This compound displays promising antipsychotic effects.
价 格:¥电议型 号:T38975产 地:中国大陆
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T384652,2-Dihydroxy-1-phenylethan-1-one;苯基乙二醛Phenylglyoxal hydrate;Phenylglyoxal hydrate|||苯基乙二醛
2,2-Dihydroxy-1-phenylethan-1-one (Phenylglyoxal hydrate) has antioxidant activity.
价 格:¥电议型 号:T38465产 地:中国大陆
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T38381CAY17cCAY17cCAY-17c|||CAY17c
CAY17c is an inhibitor of bromodomain-containing protein 4 (BRD4; IC50= 0.71 μM), as well as class I histone deacetylases (HDACs; IC50s = 0.046, 0.058, 0.075, and 0.167 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 0.073 and 0.923 μM for HDAC6 and HDAC10, respectively).1It is selective for these enzymes over BRD2, -3, and -T (IC50s = >20 μM for all), as well as over HDAC4, -5, -7, -9, and -11 (IC50s = >10 μM for all). CAY17c inhibits the proliferation of HCT116, SW620,
价 格:¥电议型 号:T38381产 地:中国大陆
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T38371CAY10734CAY10734CAY10734|||CAY-10734
CAY10734 has a wide range of applications in life science related research.
价 格:¥电议型 号:T38371产 地:中国大陆
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T38369CAY10678化合物 CAY10678CAY-10678|||CAY10678
CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS
价 格:¥电议型 号:T38369产 地:中国大陆
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T379165,6-epoxy-13-cis Retinoic Acid;5,6-epoxy-13-cis Retinoic Acid5,6-epoxy-13-cis Retinoic Acid
5,6-epoxy-13-cis Retinoic Acid is a metabolite of 13-cis retinoic acid.
价 格:¥电议型 号:T37916产 地:中国大陆