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  • T64116B-Raf IN 5；化合物 B-Raf IN 5B-Raf IN 5

    B-Raf IN 5 is a potent inhibitor of the protein kinase B-Raf (IC50: 2.0 nM). B-Raf IN 5 resists rapid metabolism and does not bind to the secondary target PXR.

    价 格：￥电议型 号：T64116产 地：中国大陆

  • T63661HF51116；化合物 HF51116HF51116

    HF51116 is a potent antagonist of XCR4. HF51116 significantly antagonizes SDF-1α-induced cell migration, calcium mobilization and CXCR4 internalization, and inhibits HIV-1 infection using CXCR4. HF51116 has shown investigational potential for HIV-1 infection, hematopoietic stem cell mobilization and cancer metastasis.

    价 格：￥电议型 号：T63661产 地：中国大陆

  • T63116TXA6101；化合物 TXA6101TXA6101

    TXA6101 is an inhibitor of the bacterial protein FtsZ (filamentous temperature sensitive protein Z). TXA6101 inhibits bacterial division and has an MIC of 1 μg/mL against MRSA isolates expressing either the G193D or G196S mutant FtsZ and retains significant activity against the TXA707 resistant FtsZ mutant. TXA6101 can be used as a potential method of resistance to Gram-negative infections.

    价 格：￥电议型 号：T63116产 地：中国大陆

  • T62116ALK5-IN-33；化合物 ALK5-IN-33ALK5-IN-33

    ALK5-IN-33 (Compound EX-10) is an orally active, selective inhibitor of ALK-5 (IC50 ≤ 10 nM).

    价 格：￥电议型 号：T62116产 地：中国大陆

  • T61754TMX-4116；化合物 TMX-4116TMX-4116

    TMX-4116, a casein kinase 1α (CK1α) degrader, preferentially degrades CK1α in MOLT4, Jurkat, and MM.1S cells, exhibiting degradation concentration 50s (DC50s) below 200 nM. TMX-4116 is utilized in the research of multiple myeloma [1].

    价 格：￥电议型 号：T61754产 地：中国大陆

  • T6116LBleomycin hydrochloride；盐酸博来霉素Bleomycin hydrochloride

    Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.

    价 格：￥电议型 号：T6116L产 地：中国大陆

  • T61169PqsR-IN-1；化合物 PqsR-IN-1PqsR-IN-1

    PqsR-IN-1 (Compound 18) is a potent inhibitor of PqsR, which is a transcriptional regulator involved in the quorum sensing mechanism of Pseudomonas aeruginosa. This compound effectively reduces the production of pyocyanin and exhibits minimal cytotoxicity [1].

    价 格：￥电议型 号：T61169产 地：中国大陆

  • T61168CAY10590；化合物 CAY10590CAY10590

    CAY10590 (GK115) is a compound that functions as an inhibitor of secreted phospholipase A2 (sPLA2). It is commonly employed in research related to chronic inflammatory kidney diseases [1].

    价 格：￥电议型 号：T61168产 地：中国大陆

  • T61167PptT-IN-1；化合物 PptT-IN-1PptT-IN-1

    PptT-IN-1 (compound 5j) is a highly potent inhibitor (IC50: 2.8 μM) of phosphopantetheinyl phosphoryl transferase (PptT), a crucial enzyme involved in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound shows considerable potential for tuberculosis research [1].

    价 格：￥电议型 号：T61167产 地：中国大陆

  • T61166α-Glucosidase-IN-16；化合物 α-Glucosidase-IN-16α-Glucosidase-IN-16

    α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose levels in diabetic rats induced by Streptozotocin. Notably, α-Glucosidase-IN-16 also exhibits noteworthy antidiabetic activity [1].

    价 格：￥电议型 号：T61166产 地：中国大陆

  • T61164hCAII-IN-3；化合物 hCAII-IN-3hCAII-IN-3

    hCAII-IN-3 (Compound 16) is an inhibitor of human carbonic anhydrase (hCA). It exhibits high affinity for hCA I, hCA II, hCA IX, and hCA XII, with Ki values of 403.8 nM, 5.1 nM, 10.2 nM, and 5.2 nM, respectively. Notably, hCA IX-IN-2 demonstrates anticancer activity [1].

    价 格：￥电议型 号：T61164产 地：中国大陆

  • T61163Protein kinase D inhibitor 1；化合物 Protein kinase D inhibitor 1Protein kinase D inhibitor 1

    Protein kinase D inhibitor 1 (compound 17m) is a potent pan-PKD inhibitor. It exhibits inhibitory activity in the low nanomolar range, with IC50 values ranging between 17 and 35 nM. By inhibiting protein kinase D, this compound effectively suppresses cortactin phosphorylation, which is known to be PKD-dependent [1].

    价 格：￥电议型 号：T61163产 地：中国大陆

  • T61162Xanthine oxidoreductase-IN-2；化合物 Xanthine oxidoreductase-IN-2Xanthine oxidoreductase-IN-2

    Xanthine oxidoreductase-IN-2 (Compound IVa) is a potent inhibitor of xanthine oxidoreductase (XOR) with an IC50 value of 7.2 nM. Notably, Xanthine oxidoreductase-IN-2 demonstrates hypouricemic effects in mice, as evidenced by [1].

    价 格：￥电议型 号：T61162产 地：中国大陆

  • T61161HIF-1α-IN-3；化合物 HIF-1α-IN-3HIF-1α-IN-3

    HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].

    价 格：￥电议型 号：T61161产 地：中国大陆

  • T61160Antiparasitic agent-2；化合物 Antiparasitic agent-2Antiparasitic agent-2

    Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it demonstrates moderate cytotoxicity against HepG2 cells with a CC50 of 26.79 μM [1].

    价 格：￥电议型 号：T61160产 地：中国大陆

  • T6116Bleomycin Sulfate；硫酸博来霉素Blenoxane|||NSC125066；Blenoxane|||硫酸博来霉素|||硫酸博莱霉素|||NSC125066

    Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.

    价 格：￥电议型 号：T6116产 地：中国大陆

  • T61116NSC405640；化合物 NSC405640NSC405640

    NSC405640 is a highly effective compound that inhibits the interaction between MDM2 and p53 proteins. Furthermore, it can restore the structural integrity of p53 molecules affected by mutations. Notably, NSC405640 exhibits selectivity in inhibiting the growth of cell lines that possess the normal, unmutated form of the p53 protein [1].

    价 格：￥电议型 号：T61116产 地：中国大陆

  • T60116Pd(OAc)2；化合物 Pd(OAc)2Palladium acetate|||Palladium(II) acetate|||Palladium diacetate；Palladium aceta

    Pd(OAc)2 can be widely used to induce or catalyze various types of organic synthesis reactions.

    价 格：￥电议型 号：T60116产 地：中国大陆

  • T60016VV116；化合物 VV116GS-621763-d1|||JT001；GS-621763-d1|||JT001

    VV116 (JT001) is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV-2 infection.

    价 格：￥电议型 号：T60016产 地：中国大陆

  • T5697BMS-1166；化合物BMS1166BMS-1166

    BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.

    价 格：￥电议型 号：T5697产 地：中国大陆

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