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T12145N-Desethyl SunitinibN-Desethyl Sunitinib,SU-11662,
N-Desethyl Sunitinib is a sunitinib metabolite.
价 格:¥电议型 号:T12145产 地:美洲
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T13178ToceranibToceranib,SU11654,PHA 291639E
Toceranib phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.
价 格:¥电议型 号:T13178产 地:美洲
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T14067A-1165442A-1165442
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
价 格:¥电议型 号:T14067产 地:美洲
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T14116ACP-105ACP-105
ACP-105 is a selective amd potent androgen receptor modulator (SARM). For AR wild type and T877A mutant, the pEC50s values are 9.0 and 9.3 , respectively.
价 格:¥电议型 号:T14116产 地:美洲
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T14325ArterolaneArterolane,OZ 277,RBx 11160
Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.
价 格:¥电议型 号:T14325产 地:美洲
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T15116Dichlorophenyl-ABADichlorophenyl-ABA
Dichlorophenyl-ABA is a transthyretin (TTR) amyloid fibril formation inhibitor. which inhibiting aggregate formation in more than 80% in TTR L55P-expressing cells .
价 格:¥电议型 号:T15116产 地:美洲
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T15247ESI-05ESI-05,NSC 116966,
ESI-05 is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 ?M). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
价 格:¥电议型 号:T15247产 地:美洲
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T15719Latanoprostene bunodLatanoprostene bunod,NCX116,LBN
Latanoprostene bunod is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT).
价 格:¥电议型 号:T15719产 地:美洲
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T16116MLN-4760MLN-4760
MLN-4760 is an effective and selective inhibitor of human ACE2 (IC50, 0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
价 格:¥电议型 号:T16116产 地:美洲
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T1619Trazodone hydrochlorideTrazodone hydrochloride,AF-1161,Trazodone HCl
Trazodone hydrochloride is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depres
价 格:¥电议型 号:T1619产 地:美洲
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T16411OtenzepadOtenzepad,AF-DX 116,
Otenzepad is a selective and competitive antagonist of M2 muscarinic acetylcholine receptors. It has IC50 values of 640 nM and 386 nM for rabbit peripheral lung and rat heart, respectively.
价 格:¥电议型 号:T16411产 地:美洲
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T16412OteseconazoleOteseconazole,VT-1161,
Oteseconazole is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM).
价 格:¥电议型 号:T16412产 地:美洲
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T16781RogaratinibRogaratinib,BAY1163877,
Rogaratinib is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity.
价 格:¥电议型 号:T16781产 地:美洲
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T2116AEE788AEE788,NVP-AEE 788,
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
价 格:¥电议型 号:T2116产 地:美洲
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T2353BRD7716BRD7716,BRD7116,
BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
价 格:¥电议型 号:T2353产 地:美洲
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T2543CabazitaxelCabazitaxel,RPR-116258A,taxoid XRP6258
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.
价 格:¥电议型 号:T2543产 地:美洲
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T5677SAR125884 hydrochlorid (1116743-46-4(free base))SAR125884 hydrochlorid (1116743-46-4(free base))
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).
价 格:¥电议型 号:T5677产 地:美洲
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T6116Bleomycin SulfateBleomycin Sulfate,NSC125066,Blenoxane
Bleomycin Sulfate, a glycopeptide antibiotic, is an anticancer agent for squamous cell carcinomas (SCC). In UT-SCC-19A cells, the IC50 of Bleomycin Sulfate is 4 nM.
价 格:¥电议型 号:T6116产 地:美洲