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T18954LCY7-SE Triethylamine (477908-53-5(free acid) )；化合物CY7-SE TriethylamineCY7-SE Triethylamine (477908-5
CY7-SE Triethylamine is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm) used for labeling proteins, peptides, antibodies, and oligonucleotides.
价 格：￥电议型 号：T18954L产 地：中国大陆
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T18477NAMPT inhibitor-linker 1；化合物 T18477NAMPT inhibitor-linker 1
NAMPT inhibitor-linker 1, a drug-linker conjugate for ADC, integrates an NAMPT inhibitor (as a payload) with a linker. In the formulation of ADC-3, it pairs with an anti-c-Kit monoclonal antibody, demonstrating strong efficacy against c-Kit expressing cell lines, specifically GIST-T1 and NCI-H526, where it exhibits IC50 values of <3 pM and 9 pM, respectively.
价 格：￥电议型 号：T18477产 地：中国大陆
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T17477Azido-PEG1-CH2COO-Cl；化合物 T17477Azido-PEG1-CH2COO-Cl
Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker, commonly employed in the synthesis of PROTAC BRD4 Degrader-1[1].
价 格：￥电议型 号：T17477产 地：中国大陆
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T16505PF-4778574；化合物 T16505PF-4778574
PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).
价 格：￥电议型 号：T16505产 地：中国大陆
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T16495PF-06747711；化合物 T16495PF-06747711
PF-06747711 is an effective and selective retinoic acid receptor-related orphan C2 inverse agonist (IC50: 4.1 nM). PF-06747711 also has anti-skin inflammatory activity.
价 格：￥电议型 号：T16495产 地：中国大陆
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T16477PF-03715455；化合物 T16477PF-03715455
PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38α over p38β (respective IC50: 0.88 and 23 nM). PF-03715455 has the potential for the treatment of COPD.
价 格：￥电议型 号：T16477产 地：中国大陆
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T16332NKH477；化合物 T16332Colforsin dapropate hydrochloride；Colforsin dapropate hydrochloride
NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts. NKH477 directly activates the catalytic unit of adenylate cyclase and enhances intracellular cAMP .
价 格：￥电议型 号：T16332产 地：中国大陆
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T16145MS-444化合物 T16145BE-34776
MS-444 suppresses the activity of purified smooth muscle myosin light chain kinase (MLCK) (IC50: 10 μM).
价 格：￥电议型 号：T16145产 地：中国大陆
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T15477Hexaminolevulinate hydrochloride；5-氨基酮戊酸己酯盐酸盐Hexyl 5-aminolevulinate hydrochloride|||5-Aminolevulini
Hexaminolevulinate hydrochloride (P-1206) has approved for cystoscopic detection of papillary bladder cancer and it also is a fluorescent agent.
价 格：￥电议型 号：T15477产 地：中国大陆
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T14779BRD7389；化合物BRD7389BRD7389
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.
价 格：￥电议型 号：T14779产 地：中国大陆
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T14778BRD6989；化合物BRD6989BRD6989
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.
价 格：￥电议型 号：T14778产 地：中国大陆
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T14777BRD5529；化合物 T14777BRD5529
BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9.
价 格：￥电议型 号：T14777产 地：中国大陆
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T14776BRD4 Inhibitor-10；化合物BRD4 Inhibitor-10BRD4 Inhibitor-10
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
价 格：￥电议型 号：T14776产 地：中国大陆
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T14775Bragsin2；化合物Bragsin26-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one|||Bragsin 2；6-methoxy-5-nitro
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.
价 格：￥电议型 号：T14775产 地：中国大陆
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T14774Bragsin1；化合物 T14774Bragsin1
Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.
价 格：￥电议型 号：T14774产 地：中国大陆
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T14773Br-PEG4-OH；化合物 T14773Br-PEG4-OH
Br-PEG4-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14773产 地：中国大陆
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T14772Br-PEG4-CH2-Boc；化合物 T14772Br-PEG4-CH2-Boc
Br-PEG4-CH2-Boc, a PEG- and Alkyl/ether-based PROTAC linker, serves as a valuable component for the synthesis of PROTACs[1].
价 格：￥电议型 号：T14772产 地：中国大陆
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T14771Br-PEG4-C2-Boc；化合物 T14771Br-PEG4-C2-Boc
Br-PEG4-C2-Boc is a cleavable 4-unit PEG ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14771产 地：中国大陆
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T14770Br-PEG3-OH；化合物 T14770Br-PEG3-OH
Br-PEG3-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14770产 地：中国大陆
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T14477Azido-PEG8-C1-NHS ester；化合物 T14477Azido-PEG8-C1-NHS ester
Azido-PEG8-C1-NHS ester is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T14477产 地：中国大陆
