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  • T63684DAD dichloride;化合物 DAD dichlorideDAD dichloride

    DAD dichloride is an ion channel blocker that blocks voltage-gated potassium channels, a third-generation photoelectric switch that responds to visible light, and can be used to study visual function.

    价 格:¥电议型 号:T63684产 地:中国大陆

  • T62684Lartesertib;化合物 LartesertibATM Inhibitor-5|||M4076;ATM Inhibitor-5|||M4076

    Lartesertib (ATM Inhibitor-5) is an inhibitor of serine/threonine protein kinase ATM with potential anticancer activity for the study of lung cancer.

    价 格:¥电议型 号:T62684产 地:中国大陆

  • T61987PHA 568487;化合物 PHA 568487PHA 568487

    PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor ( α-7 nAchR ). PHA-568487 shows rapid brain penetration. PHA 568487 reduces oxidative stress and neuroinflammation.

    价 格:¥电议型 号:T61987产 地:中国大陆

  • T61684S 17092;化合物 S 17092S 17092

    S 17092 (S 17092-1) is a highly effective inhibitor of cerebral prolyl-endopeptidase (PEP), displaying an IC50 value of 1.2 nM. It is utilized in research focused on understanding memory impairment and cognitive disorders associated with cerebral aging [1].

    价 格:¥电议型 号:T61684产 地:中国大陆

  • T60684FBA-IN-1;化合物 FBA-IN-1FBA-IN-1

    FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase(FBA) from Candida albicans(CaFBA). Furthermore, FBA-IN-1 can inhibit the Azole-resistant strains 103 growth with the MIC 80 of 1 μg/mL [1].

    价 格:¥电议型 号:T60684产 地:中国大陆

  • T5684Ethyl 3,4-dihydroxybenzoate;3,4-二羟基苯甲酸乙酯Ethyl 3,4-dihydroxybenzoate

    Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.

    价 格:¥电议型 号:T5684产 地:中国大陆

  • T4684ML241 hydrochloride;化合物ML241 hydrochlorideML241 hydrochloride

    ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97 inhibitors.

    价 格:¥电议型 号:T4684产 地:中国大陆

  • T4307PF-06840003;化合物PF06840003EOS200271|||PF 06840003;EOS200271|||PF 06840003

    PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.

    价 格:¥电议型 号:T4307产 地:中国大陆

  • T40684N-Nitrosomorpholine;N-亚硝基吗啉N-Nitrosomorpholine

    N-Nitrosomorpholine, a nitrosamine compound, exhibits sensitivity to light and is recognized as a potent carcinogen in animals.

    价 格:¥电议型 号:T40684产 地:中国大陆

  • T39960SHR168442SHR168442SHR168442

    SHR168442 is a potent RORγ modulator, exhibiting an IC50 value of 0.035 μM.

    价 格:¥电议型 号:T39960产 地:中国大陆

  • T39684AZD8154;AZD8154AZD8154;AZD8154

    AZD8154 is a newly developed inhaled compound that selectively inhibits dual PI3Kγδ, aimed at treating airway inflammatory diseases.

    价 格:¥电议型 号:T39684产 地:中国大陆

  • T38684AKR1C3-IN-4;化合物AKR1C3-IN-4AKR1C3-IN-4;AKR1C3-IN-4

    AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.

    价 格:¥电议型 号:T38684产 地:中国大陆

  • T37684CAY10412;CAY10412CAY10412;CAY10412

    Anandamide (arachidonoyl ethanolamide; AEA) is an endogenous lipid with cannabinergic activity; along with 2-arachidonoyl glycerol, it forms part of the endocannabinoid system. AEA undergoes reuptake into neurons by a facilitated process. Controversy exists as to whether there is a specific AEA transporter, or instead the uptake process is simply driven by hydrolysis of AEA by intracellular fatty acyl amide hydrolase (FAAH). CAY10412 is an analog of AEA that has no intrinsic binding affinity for

    价 格:¥电议型 号:T37684产 地:中国大陆

  • T368663-Deazauridine;4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮NSC 126849;4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮|||NSC 126849

    3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5´-Triphosphate by competitive inhibition of Cytidine Triphosphate synthetase which is considered to be the primary mode of action of this nucleoside analog.

    价 格:¥电议型 号:T36866产 地:中国大陆

  • T36849Corynecin V;Corynecin VCorynecin V

    Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.

    价 格:¥电议型 号:T36849产 地:中国大陆

  • T36848Combretastatin A-1;康普瑞汀A-1Combretastatin A1;Combretastatin A1

    Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and can be used to study hepatocellular carcinoma.

    价 格:¥电议型 号:T36848产 地:中国大陆

  • T36847Coelenterazine hcp;Coelenterazine hcpCoelenterazine hcp

    Coelenterazine hcp is a synthetic bioluminescent luciferin that displays an emission maximum of 445 nm.1It has been used as a calcium indicator and substrate to quantifyRenillaluciferase activity.1,2,3

    价 格:¥电议型 号:T36847产 地:中国大陆

  • T36846Chromomycin A2Chromomycin A2Chromomycin A-2|||Chromomycin A2

    Chromomycin A2 is an aureolic acid that has been found in several marine actinomycetes and has antibacterial and anticancer activities. Chromomycin A2 inhibits the growth of B. subtilis in an agar diffusion assay. It also inhibits the growth of human SGC7901 gastric cancer, HepG2 hepatocellular carcinoma, A549 lung epithelial adenocarcinoma, HCT116 colon cancer, and COC1 ovarian cancer cells, as well as human umbilical vein endothelial cells (HUVECs; IC50s = 4, 0.5, 3, 5, 5, and 8 nM, respective

    价 格:¥电议型 号:T36846产 地:中国大陆

  • T36845Isogarcinol;IsogarcinolIsogarcinol

    Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental auto

    价 格:¥电议型 号:T36845产 地:中国大陆

  • T36844Inostamycin A;Inostamycin AInostamycin A

    Inostamycin A is a bacterial metabolite that has been found inStreptomycesand has anticancer activity.1It is an inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase (IC50= 0.02 μg/ml in A431 cell membranes) and is selective for CDP-diacylglycerol:inositol 3-phosphatidyltransferase over phospholipase C (PLC) and phosphatidylinositol kinase at 10 μg/ml.2Inostamycin A decreases viability of YCU-T892, KCC-TC873, KB, HSC-4, and YCU-T891 oral squamous cell carcinoma (OSCC) cells in a con

    价 格:¥电议型 号:T36844产 地:中国大陆

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