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T16844Sarmazenil;沙马西尼R-154513|||Ro 15-3505;R-154513|||Ro 15-3505
Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor with pro-convulsant properties and is used in the study of chronic hepatic encephalopathy (HE).
价 格:¥电议型 号:T16844产 地:中国大陆
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T16843Saridegib化合物 T16843IPI-926|||Patidegib
Saridegib is an effective and specific inhibitor of Smoothened and a key signaling transmembrane protein in the Hedgehog pathway.
价 格:¥电议型 号:T16843产 地:中国大陆
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T16842Saredutant;化合物 T16842SR 48968C|||SR 48968;SR 48968C|||SR 48968
Saredutant is an antagonist of selective NK2 receptors.
价 格:¥电议型 号:T16842产 地:中国大陆
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T16841SAR-260301;化合物 T16841SAR-260301
SAR-260301 is an orally available and selective inhibitor of PI3Kβ (IC50: 23 nM).
价 格:¥电议型 号:T16841产 地:中国大陆
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T16840Sampatrilat;化合物 T16840UK-81252;UK-81252
Sampatrilat is an effecive and orally active vasopeptidase inhibitor of ACE and neutral endopeptidase. Sampatrilat inhibits C-domain ACE (Ki=13.8 nM) 12.4-fold more potent than that for the N-domain (Ki=171.9 nM).
价 格:¥电议型 号:T16840产 地:中国大陆
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T1684Nitisinone;尼替西农NTBC|||SC0735|||Nitisone;尼替西农|||NTBC|||SC0735|||Nitisone
Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
价 格:¥电议型 号:T1684产 地:中国大陆
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T16684Puromycin aminonucleoside维生素E醋酸酯维生素E醋酸酯|||NSC 3056
Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.
价 格:¥电议型 号:T16684产 地:中国大陆
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T16491PF-06446846 hydrochloride;化合物PF-06446846盐酸盐PF-06446846 hydrochloride
PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.
价 格:¥电议型 号:T16491产 地:中国大陆
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T15684L-689560;化合物L-689560L-689560
L-689560 is widely used as a radiolabeled ligand in binding studies and used to study the roles of NMDA receptors in normal neurological processes as well as in diseases. At the GluN1 glycine binding site, L-689560 is an effective N-methyl-D-aspartate (NMDA) receptor antagonist.
价 格:¥电议型 号:T15684产 地:中国大陆
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T14684BMS-986120;化合物 T14684BMS-986120
BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 (PAR4) antagonist. With IC50s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatelet effects[1][2].
价 格:¥电议型 号:T14684产 地:中国大陆
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T13684Equilin;马烯雌酮7-Dehydroestrone;7-Dehydroestrone
Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity that increases monocyte-endothelial adhesion through NF-κB signalling.Equilin similarly relaxes mesenteric arterial resistance by blocking Ca(2+) entry into smooth muscle.
价 格:¥电议型 号:T13684产 地:中国大陆
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T131684Compound 0120-0018;化合物 0120-0018Compound 0120-0018
Compound 0120-0018 is a useful organic compound for research related to life sciences and the catalog number is T131684.
价 格:¥电议型 号:T131684产 地:中国大陆
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T12684Radioprotectin-1;化合物Radioprotectin-15-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
价 格:¥电议型 号:T12684产 地:中国大陆
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T125684Maceneolignan B;化合物 Maceneolignan BMaceneolignan B
Maceneolignan B is a useful organic compound for research related to life sciences and the catalog number is T125684.
价 格:¥电议型 号:T125684产 地:中国大陆
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T124684Mi-Saponin A;化合物 Mi-Saponin AMi-Saponin A
Mi-Saponin A is a useful organic compound for research related to life sciences. The catalog number is T124684 and the CAS number is 54328-42-6.
价 格:¥电议型 号:T124684产 地:中国大陆
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T12195NCI172112;化合物 T12195NSC268497|||NSC172112;NSC268497|||NSC172112
NCI172112 is is used to develop antitumor agents effective against CNS tumors.
价 格:¥电议型 号:T12195产 地:中国大陆
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T11684Isoguvacine hydrochloride;异四氢烟酸1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride;1,2,3,6-te
Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2S, α5β2γ2S, and ρ1 subunit GABAA receptors.
价 格:¥电议型 号:T11684产 地:中国大陆
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T11442GNE684;化合物 T11442GNE684
GNE684 is a potent inhibitor of potent receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM, 189 nM and 691 nM for human mouse and rat RIP1, respectively [1].
价 格:¥电议型 号:T11442产 地:中国大陆
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T11390GENZ-882706;化合物 T11390RA03546849;RA03546849
GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.
价 格:¥电议型 号:T11390产 地:中国大陆
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T10684LCarnostatine hydrochloride;化合物 T10684LSAN9812 hydrochloride;SAN9812 hydrochloride
Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent, selective inhibitor of carnosinase 1 (CN1), exhibiting a K_i of 11 nM against human recombinant CN1. This compound shows promise for the treatment of diabetic nephropathy (DN) [1].
价 格:¥电议型 号:T10684L产 地:中国大陆