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T18797Tetrazine-Ph-NHCO-PEG4-NH-Boc;化合物 T18797Tetrazine-Ph-NHCO-PEG4-NH-Boc
Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEGylated PROTAC linker suitable for PROTAC synthesis[1].
价 格:¥电议型 号:T18797产 地:中国大陆
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T18697SNIPER(ER)-87;化合物 T18697SNIPER(ER)-87
SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (ERα) ligand 4-hydroxytamoxifen using a PEG linker. It effectively degrades the ERα protein with an IC50 value of 0.097 μM. Within cells, SNIPER(ER)-87 selectively recruits XIAP to ERα, and XIAP functions as the primary E3 ubiquitin ligase responsible for the degradation of ERα induced by SNIPER(ER)-87[1][2].
价 格:¥电议型 号:T18697产 地:中国大陆
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T18597dFKBP-1;化合物 T18597dFKBP-1
dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
价 格:¥电议型 号:T18597产 地:中国大陆
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T1858CID-797718;化合物CID 797718CID 797718;CID 797718
CID-797718 is a protein kinase D1 (PKD1) inhibitor.
价 格:¥电议型 号:T1858产 地:中国大陆
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T18497NHPI-PEG2-C2-Pfp ester;化合物 T18497NHPI-PEG2-C2-Pfp ester
NHPI-PEG2-C2-Pfp ester is a noncleavable 2-unit polyethylene glycol (PEG) linker widely employed in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18497产 地:中国大陆
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T18297Mal-PEG6-mal;化合物 T18297Mal-PEG6-mal
Mal-PEG6-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18297产 地:中国大陆
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T18197m-PEG37-hydrazide;化合物 T18197m-PEG37-hydrazide
m-PEG37-hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18197产 地:中国大陆
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T18097m-PEG-NH2 (MW 1000);化合物 T18097m-PEG-NH2 (MW 1000)
m-PEG-NH2 (MW 1000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18097产 地:中国大陆
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T17997HO-PEG-amine (MW 1000);化合物 T17997HO-PEG-amine (MW 1000)
HO-PEG-amine (MW 1000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17997产 地:中国大陆
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T17979Fmoc-PEG24-NHS ester;化合物 T17979Fmoc-PEG24-NHS ester
Fmoc-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17979产 地:中国大陆
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T17978Fmoc-PEG12-NHS ester;化合物Fmoc-PEG12-NHS esterFmoc-PEG12-NHS ester
Fmoc-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17978产 地:中国大陆
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T17977Fmoc-PEA;化合物Fmoc-PEAFmoc-PEA
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC).
价 格:¥电议型 号:T17977产 地:中国大陆
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T17976Fmoc-NMe-PEG4-NHS ester;化合物 T17976Fmoc-NMe-PEG4-NHS ester
Fmoc-NMe-PEG4-NHS ester is a PEG-derived PROTAC linker employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T17976产 地:中国大陆
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T17975Fmoc-NH-pentanoic acid-NHS-SO3Na;化合物 T17975Fmoc-NH-pentanoic acid-NHS-SO3Na
Fmoc-NH-pentanoic acid-NHS-SO3Na is a PROTAC linker molecule derived from an alkyl chain. It possesses the ability to facilitate the synthesis of PROTACs[1].
价 格:¥电议型 号:T17975产 地:中国大陆
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T17974Fmoc-NH-PEG4-alcohol;化合物 T17974Fmoc-NH-PEG4-alcohol
Fmoc-NH-PEG4-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17974产 地:中国大陆
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T17973Fmoc-NH-PEG30-CH2CH2COOH;化合物 T17973Fmoc-NH-PEG30-CH2CH2COOH
Fmoc-NH-PEG30-CH2CH2COOH is a PEGylation-based PROTAC linker employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T17973产 地:中国大陆
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T17972Fmoc-NH-PEG3-C2-NH2;化合物 T17972Fmoc-NH-PEG3-C2-NH2
Fmoc-NH-PEG3-C2-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17972产 地:中国大陆
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T17971Fmoc-NH-PEG25-CH2CH2COOH;化合物 T17971Fmoc-NH-PEG25-CH2CH2COOH
Fmoc-NH-PEG25-CH2CH2COOH, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].
价 格:¥电议型 号:T17971产 地:中国大陆
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T17970Fmoc-NH-PEG19-CH2CH2COOH;化合物 T17970Fmoc-NH-PEG19-CH2CH2COOH
Fmoc-NH-PEG19-CH2CH2COOH is a Polyethylene Glycol (PEG)-based linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T17970产 地:中国大陆
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T1797Cabozantinib S-malate;卡博替尼苹果酸盐Cabozantinib|||XL184|||Cabozantinib Malate;苹果酸卡博替尼|||Cabozantinib|||卡博
Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
价 格:¥电议型 号:T1797产 地:中国大陆