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T17897cIAP1 Ligand-Linker Conjugates 13;化合物 T17897E3 ligase Ligand-Linker Conjugates 43;E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1].
价 格:¥电议型 号:T17897产 地:中国大陆
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T17797DBCO-PEG4-NH-Boc;化合物 T17797DBCO-PEG4-NH-Boc
DBCO-PEG4-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17797产 地:中国大陆
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T17697BRD7-IN-1;化合物BRD7-IN-1BRD7-IN-1
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 through linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1].
价 格:¥电议型 号:T17697产 地:中国大陆
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T17597Biotin-PEG9-CH2CH2COOH;化合物 T17597Biotin-PEG9-CH2CH2COOH
Biotin-PEG9-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17597产 地:中国大陆
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T1750Pirodavir;吡罗达韦R77975;R77975|||吡罗达韦
Pirodavir (R77975) (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor.
价 格:¥电议型 号:T1750产 地:中国大陆
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T17497Azido-PEG24-alcohol;化合物 T17497Azido-PEG24-alcohol
Azido-PEG24-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17497产 地:中国大陆
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T17397Amine-PEG-CH2COOH (MW 2000);化合物Amine-PEG-CH2COOH (MW 2000)Amine-PEG-CH2COOH (MW 5000);Amine-PEG-CH2C
Amine-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17397产 地:中国大陆
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T17300(-)-(S)-B-973B;化合物(-)-(S)-B-973B(-)-(S)-B-973B
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
价 格:¥电议型 号:T17300产 地:中国大陆
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T17297ZXH-3-26;化合物 T17297ZXH-3-26
ZXH-3-26 is a selective degrader of the PROTAC BRD4 (DC50/5h: ~ 5 nM).
价 格:¥电议型 号:T17297产 地:中国大陆
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T17197UCL 2077;化合物UCL 2077UCL 2077
UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker,with IC50 of 500 nM in hippocampal neurons in culture, having minimal effects on Ca2+ channels, action potentials, input resistance, and the medium afterhyperpolarization.
价 格:¥电议型 号:T17197产 地:中国大陆
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T17101Tiopinac;硫平酸RS 40974|||RS40974|||硫平酸|||RS-40974|||RS 40974|||Tiopinac|||RS 40974|||Tiopinac;RS 40974
Tiopinac is a tricyclic compound with potent anti-inflammatory, analgesic and antipyretic effects in animals, the ability to inhibit prostaglandin synthesis, and moderate anti-platelet aggregation properties in humans.
价 格:¥电议型 号:T17101产 地:中国大陆
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T17097Tilbroquinol;甲溴羟喹Tilbroquinol
Tilbroquinol is an antiprotozoal agent effective against amoebiasis.
价 格:¥电议型 号:T17097产 地:中国大陆
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T17032Telratolimod;化合物TelratolimodMEDI9197|||3M-052;MEDI9197|||3M-052
Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.
价 格:¥电议型 号:T17032产 地:中国大陆
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T16999Tavapadon;化合物TavapadonPF-6649751|||CVL-751;PF-6649751|||CVL-751
Tavapadon (CVL-751) is an orally active and highly selective dopamine D1/D5 receptor partial agonist.
价 格:¥电议型 号:T16999产 地:中国大陆
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T16997Tasidotin hydrochloride;化合物 T16997ILX651;ILX651
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and microtubule dynamics.
价 格:¥电议型 号:T16997产 地:中国大陆
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T16979Talazoparib tosylate化合物 T16979BMN 673ts
Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1).
价 格:¥电议型 号:T16979产 地:中国大陆
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T16978Talaporfin sodium;他拉泊芬钠ME2906|||NPe6|||Mono-L-aspartyl chlorin e6;ME2906|||他拉泊芬钠|||NPe6|||Mono-L-asp
Talaporfin is a photosensitizer used in photodynamic therapy.
价 格:¥电议型 号:T16978产 地:中国大陆
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T16977Talampanel;化合物TalampanelGYKI-53773|||LY-300164;GYKI-53773|||LY-300164
Talampanel (LY-300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models.
价 格:¥电议型 号:T16977产 地:中国大陆
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T16976TAK-915;化合物 T16976TAK-915
TAK-915 is a potent, selective, and brain-penetrant phosphodiesterase 2A (PDE2A) inhibitor (IC50: 0.61 nM). TAK-915 is >4100-fold more selectivity for PDE2A than PDE1A.
价 格:¥电议型 号:T16976产 地:中国大陆
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T16975TAK-593;化合物TAK-593TAK-593
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).
价 格:¥电议型 号:T16975产 地:中国大陆