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T15297Fluorescein-thiourea-PEG2-azide；化合物 T15297Fluorescein-thiourea-PEG2-azide
Fluorescein-thiourea-PEG2-azide is a PEG-derived linker commonly applied for the synthesis of PROTACs[1].
价 格：￥电议型 号：T15297产 地：中国大陆
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T15280Fiacitabine；非西他滨FOAC|||FIAC|||NSC 382097；非西他滨|||FOAC|||FIAC|||NSC 382097
Fiacitabine (NSC-382097) is a selective inhibitor of DNA replication of the herpes simplex virus(HSV) (IC50: 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively).
价 格：￥电议型 号：T15280产 地：中国大陆
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T15276Ferroquine；二茂铁氯喹SSR97193|||Ferrochloroquine；SSR97193|||Ferrochloroquine
Ferroquine (Ferrochloroquine) is a ferrocenyl analogue of Chloroquine with antimalarial activity. Ferroquine induces oxidative stress and the subsequent destruction of the membrane, resulting in parasiticidal effect on Plasmodium.
价 格：￥电议型 号：T15276产 地：中国大陆
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T15262Vactosertib Hydrochloride化合物 T15262TEW-7197 Hydrochloride|||EW-7197 Hydrochloride
Vactosertib Hydrochloride is an orally active and ATP-competitive ALK5 inhibitor (IC50: 12.9 nM). It has potently antimetastatic activity and anticancer effect. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50: 17.3 nM).
价 格：￥电议型 号：T15262产 地：中国大陆
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T15244Ertugliflozin L-pyroglutamic acid；埃格列净PF-04971729 L-pyroglutamic acid；埃格列净|||PF-04971729 L-pyrogluta
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.
价 格：￥电议型 号：T15244产 地：中国大陆
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T15197Echinomycin；化合物 T15197Quinomycin A|||NSC-13502；Quinomycin A|||NSC-13502
Echinomycin is a cell-permeable hypoxia-inducible factor-1 (HIF-1) DNA-binding activity inhibitor. Echinomycin selectively inhibits the cancer stem cells (CSCs; IC50: 29.4 pM).
价 格：￥电议型 号：T15197产 地：中国大陆
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T15181DuP-697；化合物DuP-697DuP-697
DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic, anti-inflammatory, antipyretic and apoptotic effects.
价 格：￥电议型 号：T15181产 地：中国大陆
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T15097Deoxynivalenol脱氧雪腐镰刀菌烯醇Vomitoxin|||4-Deoxynivalenol
Deoxynivalenol (Vomitoxin) is a mycotoxin produced by Fusarium spp. of the single trichothecene family and is commonly found in contaminated food and feed.Deoxynivalenol crosses the intestinal mucosa via a cellular bypass at the tight junctions.Deoxynivalenol transporters are unaffected by inhibitors of P-glycoprotein (PgP) or multidrug resistance-associated protein (MRP). Deoxynivalenol commonly causes diarrhea, vomiting, and gastrointestinal inflammation in humans and animals.
价 格：￥电议型 号：T15097产 地：中国大陆
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T15000Cort108297；化合物Cort108297Cort108297
Cort108297 is a selective glucocorticoid receptor modulator and a selective GR antagonist with no affinity for other steroid receptors. Cort108297 showed a high affinity for GRs (Ki: 0.45nM).
价 格：￥电议型 号：T15000产 地：中国大陆
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T14997Conteltinib；化合物 ConteltinibSY-707|||CT-707；SY-707|||CT-707
Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.
价 格：￥电议型 号：T14997产 地：中国大陆
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T14986CMI977；化合物 T14986LDP977；LDP977
CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).
价 格：￥电议型 号：T14986产 地：中国大陆
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T14979Clavulanate lithium；克拉维酸锂Clavulanic acid lithium；Clavulanic acid lithium|||克拉维酸锂
Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase.
价 格：￥电议型 号：T14979产 地：中国大陆
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T14978CL-82198；化合物CL-82198CL-82198
CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA). Its mechanism of action involves binding to the S1’ pocket of MMP-13, ensuring its selectivity and preventing inhibition of other MMPs.
价 格：￥电议型 号：T14978产 地：中国大陆
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T14977CL-275838；化合物 T14977CL-275838
CL-275838 is a compound of memory-enhancing with potent antidepressant activities.
价 格：￥电议型 号：T14977产 地：中国大陆
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T14976CKD-519；化合物 T14976CKD-519
CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM).
价 格：￥电议型 号：T14976产 地：中国大陆
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T14975CJ-42794；化合物CJ-42794CJ-042794；CJ-042794
CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3) (IC50 : 8.5 (pKi )).
价 格：￥电议型 号：T14975产 地：中国大陆
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T14974Citenamide；西替酰胺Cytenamide|||AY-15613；Cytenamide|||AY-15613
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.
价 格：￥电议型 号：T14974产 地：中国大陆
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T14973CITCO；化合物CITCOCITCO
CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist.
价 格：￥电议型 号：T14973产 地：中国大陆
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T14972Cirazoline hydrochloride；化合物 T14972LD 3098 hydrochloride；LD 3098 hydrochloride
Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).
价 格：￥电议型 号：T14972产 地：中国大陆
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T14971CIQ；化合物CIQCIQ
CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. EC50 value: 2.7 μM for NR2C and 2.8 μM for NR2D.
价 格：￥电议型 号：T14971产 地：中国大陆
