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T14970Cipralisant;化合物 T14970GT-2331;GT-2331
Cipralisant is a selective histamine H3 receptor antagonist in vivo, and an agonist in vitro (pKi: 9.9 for histamine H3 receptor; Ki: 0.47 nM for rat histamine H3 receptor). It has the potential for the treatment of attention-deficit hyperactivity disorder.
价 格:¥电议型 号:T14970产 地:中国大陆
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T1497Liranaftate;利拉萘酯Piritetrate|||M-732;Piritetrate|||利拉萘酯|||M-732
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.
价 格:¥电议型 号:T1497产 地:中国大陆
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T14964CI 972 anhydrous;化合物 T14964CI 972 (anhydrous);CI 972 (anhydrous)
CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
价 格:¥电议型 号:T14964产 地:中国大陆
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T14897CCG-63802;化合物CCG-63802CCG-63802
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins. CCG-63802 inhibits the interaction between RGS4 and Galpha with an IC50 value of 1.4 μM.
价 格:¥电议型 号:T14897产 地:中国大陆
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T14767BP 897 hydrochloride;化合物BP 897 hydrochlorideBP 897 hydrochloride
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
价 格:¥电议型 号:T14767产 地:中国大陆
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T14697BnO-PEG1-CH2COOH;化合物 T14697BnO-PEG1-CH2COOH
BnO-PEG1-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14697产 地:中国大陆
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T14690BMS 433796;化合物BMS 433796BMS-289948|||BMS-299897;BMS-289948|||BMS-299897
BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T14690产 地:中国大陆
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T14683BMS-983970;化合物 T14683BMS-983970
BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.
价 格:¥电议型 号:T14683产 地:中国大陆
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T1468Lornoxicam;氯诺昔康Ro 13-9297|||Chlortenoxicam|||TS110;Ro 13-9297|||Chlortenoxicam|||TS110|||氯诺昔康
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
价 格:¥电议型 号:T1468产 地:中国大陆
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T14674BMS-509744;化合物 T14674BMS-509744
BMS-509744 is an inhibitor of ATP competitive Itk (IC50: 19 nM).
价 格:¥电议型 号:T14674产 地:中国大陆
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T14673BMS 299897;化合物BMS 299897BMS 299897
BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor protein (APP).
价 格:¥电议型 号:T14673产 地:中国大陆
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T1461Candesartan坎地沙坦CV 11974|||坎地沙坦
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
价 格:¥电议型 号:T1461产 地:中国大陆
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T14597Biotin-PEG4-acid;化合物 T14597Biotin-PEG4-acid
Biotin-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14597产 地:中国大陆
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T14529LBentiromide acetate;苯替酪胺醋酸盐Bentiromide acetate(37106-97-1 Free base);Bentiromide acetate(37106-97-1
Bentiromide acetate is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is broken down by the pancreatic enzyme chymotrypsin, yielding p-aminobenzoic acid (PABA).
价 格:¥电议型 号:T14529L产 地:中国大陆
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T14497BAM 15;化合物BAM 15BAM 15
BAM 15 is an uncoupler of mitochondrial protonophore.
价 格:¥电议型 号:T14497产 地:中国大陆
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T14397Azide-PEG5-Tos;化合物 T14397Azide-PEG5-Tos
Azide-PEG5-Tos is a cleavable PEG linker consisting of five units, employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14397产 地:中国大陆
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T14384AZD8797;化合物KAND567KAN-0440567|||KAND567;KAN-0440567|||KAND567
AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2, and potentially protects against SARS-CoV-2-induced neuronal damage, preventing worsening of nociceptive sensitization and microglial activation in a migraine model of rats following seizures.
价 格:¥电议型 号:T14384产 地:中国大陆
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T14372AZD1979;化合物 T14372AZD1979
AZD1979 is an antagonist of Melanin-concentrating hormone receptor 1 (MCHr1) (IC50: 12 nM).
价 格:¥电议型 号:T14372产 地:中国大陆
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T14297AP1867;化合物 T14297AP1867
AP1867 is a synthetic FKBP12F36V-directed ligand.
价 格:¥电议型 号:T14297产 地:中国大陆
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T14197LAlvameline maleate;化合物 T14197LLu 25-109-M;Lu 25-109-M
Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.
价 格:¥电议型 号:T14197L产 地:中国大陆