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T15971Mal-NH-ethyl-SS-propionic acid;化合物 T15971Mal-NH-ethyl-SS-propionic acid
Mal-NH-ethyl-SS-propionic acid, a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1], plays a crucial role in the modulation of drug release from the conjugate.
价 格:¥电议型 号:T15971产 地:中国大陆
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T15970Mal-NH-Boc;化合物 T15970Mal-NH-Boc
Mal-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15970产 地:中国大陆
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T1597Proadifen hydrochloride;盐酸丙基解痉素U-5446|||RP-5171|||SKF-525A;U-5446|||RP-5171|||SKF-525A|||盐酸丙基解痉素
Proadifen hydrochloride (RP-5171) is an inhibitor of drug metabolism and cytochrome P-450 enzyme system activity.
价 格:¥电议型 号:T1597产 地:中国大陆
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T15944M77976;化合物M77976M77976
M77976 is a selective ATP-competitive inhibitor of pyruvate dehydrogenase kinase 4 (PDK4) with an inhibitory effect on PDK4, having an IC50 value of 648 μM. It is used for research related to obesity and diabetes.
价 格:¥电议型 号:T15944产 地:中国大陆
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T15897m-PEG5-nitrile;化合物 T15897m-PEG5-nitrile
m-PEG5-nitrile is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15897产 地:中国大陆
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T15812LY2979165;化合物LY2979165mGlu2 agonist;mGlu2 agonist
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
价 格:¥电议型 号:T15812产 地:中国大陆
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T15797LX2761;化合物 T15797LX2761
LX2761 is a chemically stable and effective inhibitor against sodium-dependent glucose cotransporter 1 (SGLT1) and SGLT2 (IC50s: 2.2 nM and 2.7nM for hSGLT1 and hSGLT2). However, it shows specific SGLT1 inhibition in the gastrointestinal (GI) tract.
价 格:¥电议型 号:T15797产 地:中国大陆
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T15770(Rac)-CP-609754;化合物 T15770LNK754;LNK754
LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer´s disease.
价 格:¥电议型 号:T15770产 地:中国大陆
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T15759Lintitript;林替曲特SR 27897;SR 27897|||林替曲特
Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.
价 格:¥电议型 号:T15759产 地:中国大陆
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T15746Lexibulin dihydrochloride;化合物 T15746CYT-997 dihydrochloride;CYT-997 dihydrochloride
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines). It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
价 格:¥电议型 号:T15746产 地:中国大陆
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T15697L-NMMA acetate;化合物L-NMMA acetateTilarginine acetate|||Methylarginine acetate;Tilarginine acetate|||M
L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 ?M for nNOS, eNOS, and iNOS, respectively.
价 格:¥电议型 号:T15697产 地:中国大陆
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T1566Aripiprazole;阿立哌唑OPC-14597;阿立哌唑|||OPC-14597
Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A.
价 格:¥电议型 号:T1566产 地:中国大陆
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T15597ISA-2011B;化合物ISA-2011BISA-2011B
ISA-2011B is an inhibitor of PIP5K1α and can be used in anticancer studies.
价 格:¥电议型 号:T15597产 地:中国大陆
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T15591Ipenoxazone;伊培沙宗NC-1200|||MLV-6976;NC-1200|||MLV-6976|||伊培沙宗
Ipenoxazone is an effective and centrally acting muscle relaxant.
价 格:¥电议型 号:T15591产 地:中国大陆
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T15485HJC0197;化合物HJC0197HJC0197
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).
价 格:¥电议型 号:T15485产 地:中国大陆
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T1546Nitazoxanide;硝唑尼特NSC 697855;NSC 697855|||硝唑尼特
Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction.
价 格:¥电议型 号:T1546产 地:中国大陆
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T15424GSK1379725A;化合物GSK1379725AGSK1379725A
GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
价 格:¥电议型 号:T15424产 地:中国大陆
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T15402GNE-4997;化合物 T15402GNE-4997
GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM). The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects decreases cytotoxicity.
价 格:¥电议型 号:T15402产 地:中国大陆
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T15397GNE-049;化合物 T15397GNE-049
GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay). GNE-049 also inhibits BRET and BRD4(1) (IC50s: 12 nM and 4200 nM, respectively).
价 格:¥电议型 号:T15397产 地:中国大陆
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T15388GLPG0974;化合物GLPG0974GLPG-0974;GLPG-0974
GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.
价 格:¥电议型 号:T15388产 地:中国大陆