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  • T71085BMS-824;化合物 BMS-824BMS-824

    BMS-824 is a potent NS5A inhibitor. The 50% inhibition of HCV replicon replication for BMS-824 was approximately 5 nM, with a therapeutic index of >10,000. BMS-824 showed good specificity for HCV, as it was not active against several other RNA and DNA viruses.

    价 格:¥电议型 号:T71085产 地:中国大陆

  • T71084Epiderstatin;化合物 EpiderstatinEpiderstatin

    Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.

    价 格:¥电议型 号:T71084产 地:中国大陆

  • T71083LDN-193188;化合物 LDN-193188LDN-193188

    LDN-193188 is a inhibitor of phosphatidylcholine transfer protein (PC-TP).

    价 格:¥电议型 号:T71083产 地:中国大陆

  • T71082DW532;化合物 DW532DW532

    DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 values were 4.9 and 5.5 μmol/L, respectively), and suppressed their downstream signaling. DW532 dose-dependently inhibited tubulin polymerization via direct binding to tubulin, thus disrupting the mitotic spindle assembly and leading to abnormal cell division. In a panel of human ca

    价 格:¥电议型 号:T71082产 地:中国大陆

  • T71081Nagstatin;化合物 NagstatinNagstatin

    Nagstatin is an inhibitor of N-acetyl-beta-D-glucosaminidase and is produced by Streptomyces amakusaensis MG846-fF3.

    价 格:¥电议型 号:T71081产 地:中国大陆

  • T71080IGN-2098 dihydrochloride;化合物 IGN-2098 dihydrochlorideIGN-2098 dihydrochloride

    IGN-2098 dihydrochloride is an H2-antagonist that may be useful for treatment of gastric and duodenal lesions.

    价 格:¥电议型 号:T71080产 地:中国大陆

  • T7108Omberacetam;化合物NoopeptSGS-111|||Noopept|||GVS-111;SGS-111|||Noopept|||GVS-111

    Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.

    价 格:¥电议型 号:T7108产 地:中国大陆

  • T70950BP-1-108;化合物 BP-1-108BP-1-108

    BP-1-108 is a potent and selective STAT5 inhibitor.

    价 格:¥电议型 号:T70950产 地:中国大陆

  • T7079Batefenterol;化合物BatefenterolGSK961081|||TD-5959;GSK961081|||TD-5959

    Batefenterol (TD-5959) (GSK961081, TD-5959) is a muscarinic receptor antagonist and β2-adrenoceptor agonist. It displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor (Ki:1.4/1.3/3.7 nM).

    价 格:¥电议型 号:T7079产 地:中国大陆

  • T70720CD08108;化合物 CD08108CD08108

    CD08108 is a MC1R agonist.

    价 格:¥电议型 号:T70720产 地:中国大陆

  • T70138AZ0108;化合物 AZ0108AZ0108

    AZ0108 is an orally bioavailable, potent PARP1,2,6 inhibitor that potently inhibits centrosome clustering and is suitable for in vivo efficacy and tolerability studies. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. AZ0108 is more selective in its enzyme inhibition profile and effects on cellular pathways and phenotypes. Specifically, AZ0108 inhibits PARPs 1, 2, and 6 with approxi

    价 格:¥电议型 号:T70138产 地:中国大陆

  • T70108Fasudil hydrochloride hydrate;化合物 Fasudil hydrochloride hydrateFasudil hydrochloride hydrate

    Fasudil hydrochloride hydrate is an HCl salt of Fasudil -- a Rho-kinase (ROCK) inhibitor that has been shown to be effective in hindering the development of mature Cerebral Cavernous Malformation (CCM) lesions as well as reducing portal venous pressure in cirrhotic rats.

    价 格:¥电议型 号:T70108产 地:中国大陆

  • T69696TAS-108 citrate;化合物 TAS-108 citrateTAS-108 citrate

    TAS-108, also known as SR16234, is a synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the mammary gland and uterus and upregulated in estrogen-dependent tumors. Blockage of ERa by TAS-108 prevents the binding and effects of estrogen and may lead to an inhibition of estrogen-dependent cancer cell proliferation. TAS-108 also is a partial agonist of the estrogenic receptor beta (ERb), e

    价 格:¥电议型 号:T69696产 地:中国大陆

  • T69663G108;化合物 G108G108

    G108 is a Novel h-cGAS specific inhibitor for repression of dsDNA-triggered interferon expression (IC50 of 27.5 nM and 5150 nM for h-cGAS and m-cGAS, respectively).

    价 格:¥电议型 号:T69663产 地:中国大陆

  • T69613Ar-H047108 free base;化合物 Ar-H047108 free baseAr-H047108 free base

    Ar-H047108 free base is an imidazopyridine potassium competitive acid blocker (P-CAB). This drug may be used to treat early stellate cell activation and veno-occlusive-disease (VOD)-like hepatotoxicity.

    价 格:¥电议型 号:T69613产 地:中国大陆

  • T6958Prucalopride Succinate;琥珀酸普芦卡必利R-108512|||Resolor Succinate;琥珀酸普芦卡必利|||R-108512|||琥珀酸普卡比利|||Resolor

    Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively.

    价 格:¥电议型 号:T6958产 地:中国大陆

  • T69510BDB-108;化合物 BDB-108BDB-108

    BDB-108 is a re-activator of isopropyl-methylphosphonylated acetylcholinesterase.

    价 格:¥电议型 号:T69510产 地:中国大陆

  • T69396MLS000108969;化合物 MLS000108969MLS000108969

    MLS000108969 is a novel inhibitor of human cytomegalovirus.

    价 格:¥电议型 号:T69396产 地:中国大陆

  • T69223CC-1088;化合物 CC-1088CC-1088

    CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). SelCIDs inhibit phosphodiesterase-4 (PDE 4), an enzyme involved in tumor necrosis factor alpha (TNF alpha) production. CC-1088 inhibits production of the cytokines vascular endothelial growth factor (VEGF) (a pro-angiogenic factor) and interleukin-6 (IL-6).

    价 格:¥电议型 号:T69223产 地:中国大陆

  • T69108Nebidrazine;化合物 NebidrazineNebidrazine

    Nebidrazine is an alpha-adrenoceptor agonist.

    价 格:¥电议型 号:T69108产 地:中国大陆

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