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T6094MK-2461MK-2461,MK2461,MK 2461
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met with a mean IC50 of 2.5 nM.
价 格:¥电议型 号:T6094产 地:美洲
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T6182TirofibanTirofiban,MK383,L700462
Tirofiban (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
价 格:¥电议型 号:T6182产 地:美洲
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T6340Enalaprilat DihydrateEnalaprilat Dihydrate,MK-422,MK-422 Dihydrate
Enalaprilat(IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.
价 格:¥电议型 号:T6340产 地:美洲
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T6486Enalapril MaleateEnalapril Maleate,MK-421 (maleate),MK-421 Maleate
Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension,chronic heart failure , and diabetic nephropathy.
价 格:¥电议型 号:T6486产 地:美洲
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T8786VUT-MK142;化合物VUT-MK142VUT-MK142
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.
价 格:¥电议型 号:T8786产 地:中国大陆
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T83963Z-DEVD-FMK Caspase-3 Inhibitor;化合物 Z-DEVD-FMK Caspase-3 InhibitorZ-DEVD-FMK Caspase-3 Inhibitor
Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and considerably diminishes post-traumatic apoptosis, enhancing neurological recovery in rats before and after traumatic brain injury induction.
价 格:¥电议型 号:T83963产 地:中国大陆
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T82703CMKLR1 antagonist 1;化合物 CMKLR1 antagonist 1CMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-transfected CHO cells. It is applicable in the research of psoriasis and metabolic diseases [1].
价 格:¥电议型 号:T82703产 地:中国大陆
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T82592DEC-RVRK-CMK;化合物 DEC-RVRK-CMKDecanoyl-Arg-Val-Arg-Lys-chloromethylketone;Decanoyl-Arg-Val-Arg-Lys-ch
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone (DEC-RVRK-CMK) is a small, synthetic, irreversible cell-permeable competitive inhibitor of furin that exhibits strong antiviral activity against Zika virus (ZIKV) and Japanese encephalitis virus (JEV) [1].
价 格:¥电议型 号:T82592产 地:中国大陆
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T82449Eramkafusp Alfa;化合物 Eramkafusp AlfaEramkafusp Alfa
Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].
价 格:¥电议型 号:T82449产 地:中国大陆
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T82414Favezelimab;化合物 FavezelimabMK-4280;MK-4280
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that inhibits the LAG-3/MHC class II interaction and shows potential for use in colorectal cancer (CRC) research, particularly when combined with the PD-L1 inhibitor pembrolizumab [1] [2].
价 格:¥电议型 号:T82414产 地:中国大陆
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T81822MeOSuc-AAPF-CMK;化合物 MeOSuc-AAPF-CMKMeOSuc-Ala-Ala-Pro-Phe-CH?Cl;MeOSuc-Ala-Ala-Pro-Phe-CH?Cl
MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH2Cl) is a potent inhibitor of the enzyme proteinase K [1].
价 格:¥电议型 号:T81822产 地:中国大陆
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T81785MK-1468;化合物 MK-1468MK-1468
MK-1468, a highly selective and brain-penetrant LRRK2 inhibitor, exhibits an IC50 of 0.8 nM and is utilized in the study of Parkinson´s disease [1].
价 格:¥电议型 号:T81785产 地:中国大陆
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T81784MK-2206 free base;化合物 MK-2206 free baseMK-2206 free base
MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. It demonstrates sensitivity in various breast cancer cell lines, including those with PIK3CA mutations and those exhibiting PTEN loss, indicating its potential for anticancer activities [1] [2].
价 格:¥电议型 号:T81784产 地:中国大陆
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T81783MK2-IN-5;化合物 MK2-IN-5Hsp25 kinase inhibitor|||Mk2 pseudosubstrate;Hsp25 kinase inhibitor|||Mk2 pseud
MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway and inhibits the phosphorylation of HSP25 and HSP27 [1] [2] [3].
价 格:¥电议型 号:T81783产 地:中国大陆
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T81329Quavonlimab;化合物 QuavonlimabMK-1308;MK-1308
Quavonlimab (MK-1308) is a novel antibody targeting CTLA-4 [1].
价 格:¥电议型 号:T81329产 地:中国大陆
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T80745Z-Ala-Ala-Asp-CMK;化合物 Z-Ala-Ala-Asp-CMKZ-AAD-CMK;Z-AAD-CMK
Z-Ala-Ala-Asp-chloromethylketone (Z-AAD-CMK) is a selective inhibitor of granzyme B [1].
价 格:¥电议型 号:T80745产 地:中国大陆
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T80743Z-APF-CMK;化合物 Z-APF-CMKZ-APF-CMK
Z-APF-CMK is a selective inhibitor of the calcium (Ca2+)-regulated nuclear scaffold protease (CRNSP), as reported in reference [1].
价 格:¥电议型 号:T80743产 地:中国大陆
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T80660Z-DEVD-CMK;化合物 Z-DEVD-CMKZ-DEVD-CMK
Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].
价 格:¥电议型 号:T80660产 地:中国大陆
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T80659Z-YVAD-CMK;化合物 Z-YVAD-CMKZ-YVAD-CMK
Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].
价 格:¥电议型 号:T80659产 地:中国大陆
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T80567Boserolimab;化合物 BoserolimabMK-5890;MK-5890
Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.
价 格:¥电议型 号:T80567产 地:中国大陆