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T76251Ac-FEID-CMK;化合物 Ac-FEID-CMKAc-FEID-CMK
Ac-FEID-CMK, a potent peptide inhibitor derived from zebrafish-specific GSDMEb, effectively reduces mortality and kidney injury during septic shock by inhibiting pyroptosis and mitigating acute kidney injury (AKI) in vivo. Additionally, it suppresses the caspy2-mediated noncanonical inflammasome pathway [1].
价 格:¥电议型 号:T76251产 地:中国大陆
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T76201LEESGGGLVQPGGSMK TFA;化合物 LEESGGGLVQPGGSMK TFALEESGGGLVQPGGSMK TFA
LEESGGGLVQPGGSMK TFA, a proteolysis peptide component of Infliximab, serves for the quantitative analysis of the latter. Infliximab is a chimeric monoclonal IgG1 antibody, binding specifically to TNF-α [1].
价 格:¥电议型 号:T76201产 地:中国大陆
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T75938Z-VRPR-FMK TFA;化合物 Z-VRPR-FMK TFAZ-VRPR-FMK TFA
Z-VRPR-FMK (TFA), a selective and irreversible inhibitor of Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), is a tetrapeptide shown to provide protection against influenza A virus (IAV) infection [1].
价 格:¥电议型 号:T75938产 地:中国大陆
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T7591Coluracetam;考拉西坦MKC-231;MKC-231|||考拉西坦
Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.
价 格:¥电议型 号:T7591产 地:中国大陆
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T75812MMK1 TFA;化合物 MMK1 TFAMMK1 TFA
MMK1 TFA is a potent, selective agonist for the human formyl peptide receptor like-1 (FPRL-1/FPR2), exhibiting EC50 values of <2 nM for FPRL-1 and >10,000 nM for FPR1. This compound acts as a powerful chemotactic and calcium-mobilizing agent, effectively activating phagocytic leukocytes. It significantly enhances the Pertussis Toxin-sensitive production of proinflammatory cytokines IL-1b and IL-6 by human monocytes. Additionally, MMK1 TFA has been demonstrated to exhibit anxiolytic-like activity
价 格:¥电议型 号:T75812产 地:中国大陆
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T75706Ac-DEVD-CMK TFA;化合物 Ac-DEVD-CMK TFAAc-DEVD-CMK TFA
Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible inhibitor of caspase-3, effectively preventing apoptosis triggered by elevated glucose levels or 3,20-dibenzoate (IDB). It is applicable in diverse experimental settings to impede apoptosis, as supported by references [1] [2] [3].
价 格:¥电议型 号:T75706产 地:中国大陆
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T75629Ganoderic acid Mk;化合物 Ganoderic acid MkGanoderic acid Mk
Ganoderic acid Mk (GA-Mk), a triterpenoid acid derived from Ganoderma lucidum mycelia, exhibits potent anti-proliferative properties and can induce apoptosis in HeLa cells through a mitochondria-mediated pathway, making it significant for cervical cancer research [1] [2].
价 格:¥电议型 号:T75629产 地:中国大陆
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T73462MK-8189;化合物 MK-8189MK-8189
MK-8189 is a potent, orally active, and selective inhibitor of Phosphodiesterase 10A (PDE10A), exhibiting a K i value of 29 pM. It has potential applications in the research of schizophrenia.
价 格:¥电议型 号:T73462产 地:中国大陆
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T73438MK-3402;化合物 MK-3402MK-3402
MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .
价 格:¥电议型 号:T73438产 地:中国大陆
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T73412AAF-CMK;化合物 AAF-CMKAAF-CMK
AAF-CMK, a tripeptidylpeptidase II (TPPII) inhibitor, exhibits anti-tumor activity and induces apoptosis, making it applicable in leukemia research.
价 格:¥电议型 号:T73412产 地:中国大陆
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T73410MK-4541;化合物 MK-4541MK-4541
MK-4541 is an orally active, selective androgen receptor (AR) modulator that serves as an antagonist to inhibit 5α-reductase. It effectively inhibits proliferation and induces apoptosis in AR-positive prostate cancer cells, significantly reducing the growth of R3327-G prostate tumors in a xenograft mouse model.
价 格:¥电议型 号:T73410产 地:中国大陆
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T73096Z-LEVD-FMK;化合物 Z-LEVD-FMKZ-LEVD-FMK
Z-LEVD-FMK, a cell-permeable caspase-4 inhibitor, effectively blocks endoplasmic reticulum (ER) stress-induced apoptosis in cancer cells.
价 格:¥电议型 号:T73096产 地:中国大陆
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T73093Z-VRPR-FMK;化合物 Z-VRPR-FMKZ-VRPR-FMK
Z-VRPR-FMK, an irreversible inhibitor of the MALT1 protein, effectively suppresses the proliferation and invasion of diffuse large B-cell lymphoma. This is achieved through the inhibition of MALT1-induced NF-κB activation and MMP (matrix metalloproteinase) expression.
价 格:¥电议型 号:T73093产 地:中国大陆
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T72745Acipimox sodium;化合物 Acipimox sodiumK-9321 sodium;K-9321 sodium
Acipimox (K-9321) sodium, a nicotinic acid analogue, functions as an antilipolytic agent by stimulating leptin release, inhibiting lipolysis, and reducing systemic free fatty acids (FFAs) levels, thereby enhancing insulin sensitivity.
价 格:¥电议型 号:T72745产 地:中国大陆
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T72435Z-LE(OMe)TD(OMe)-FMK;化合物 Z-LE(OMe)TD(OMe)-FMKZ-LE(OMe)TD(OMe)-FMK
Z-LE(OMe)TD(OMe)-FMK is a selective inhibitor of caspase-8, effectively inhibiting cellular apoptosis.
价 格:¥电议型 号:T72435产 地:中国大陆
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T72399LIMK1 inhibitor BMS-4;化合物 LIMK1 inhibitor BMS-4LIMK1 inhibitor BMS-4
LIMK1 inhibitor BMS-4 is a compound targeting LIM Kinase (LIMK) 1/2, specifically inhibiting the phosphorylation of its substrate, cofilin, but it remains noncytotoxic on A549 cells.
价 格:¥电议型 号:T72399产 地:中国大陆
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T72281Caspase-9 Inhibitor III;化合物 Caspase-9 Inhibitor IIIAc-LEHD-cmk;Ac-LEHD-cmk
Caspase-9 Inhibitor III (Ac-LEHD-cmk), a caspase-9 inhibitor, exhibits protective effects against ischemia-reperfusion-induced myocardial injury.
价 格:¥电议型 号:T72281产 地:中国大陆
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T72145Montelukast dicyclohexylamine;化合物 Montelukast dicyclohexylamineMK0476 dicyclohexylamine;MK0476 dicyc
Montelukast dicyclohexylamine (MK0476), a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), is utilized in the research of asthma, liver injury, and COVID-19. It exhibits antioxidant properties in the context of intestinal ischemia-reperfusion injury and can mitigate cardiac damage. Additionally, it reduces eosinophil infiltration in the airways of asthmatic patients.
价 格:¥电议型 号:T72145产 地:中国大陆
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T72111Ala-Ala-Pro-Val-chloromethylketone;化合物 Ala-Ala-Pro-Val-chloromethylketoneAAPV-CMK;AAPV-CMK
Ala-Ala-Pro-Val-chloromethylketone serves as an irreversible inhibitor of human neutrophil elastase (NE), utilized in researching chronic inflammatory airway diseases.
价 格:¥电议型 号:T72111产 地:中国大陆
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T71613MK-8712;化合物 MK-8712MK-8712
MK-8712 is a monobactam beta-lactamase inhibitor.
价 格:¥电议型 号:T71613产 地:中国大陆