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T60515CaMKIIα-IN-1;化合物 CaMKIIα-IN-1CaMKIIα-IN-1
CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub. CaMKIIα-IN-1 shows good metabolic stability [1].
价 格:¥电议型 号:T60515产 地:中国大陆
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T60496Ketorolac hemicalcium;化合物 Ketorolac hemicalciumKetorolac hemicalcium
Ketorolac (RS37619) hemicalcium is a nonselective COX inhibitor with IC50s of 20 nM and 120 nM for COX-1 and COX-2, respectively. Ketorolac hemicalcium is a non-steroidal anti-inflammatory drug (NSAID) that is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac hemicalcium is also a DDX3 inhibitor that can be used in cancer research [1] [4].
价 格:¥电议型 号:T60496产 地:中国大陆
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T6035Odanacatib;奥当卡替MK-0822;奥达卡替|||奥当卡替|||MK-0822
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
价 格:¥电议型 号:T6035产 地:中国大陆
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T6032Birabresib;化合物BirabresibOTX-015|||OTX015 (MK 8628/Birabresib)|||MK-8628;OTX-015|||OTX015 (MK 8628/Bi
Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity.
价 格:¥电议型 号:T6032产 地:中国大陆
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T6013Z-VAD(OMe)-FMK;化合物Z-VAD(OMe)-FMKZ-VAD-FMK|||Z-Val-Ala-Asp(OMe)-FMK;Z-VAD-FMK|||Z-Val-Ala-Asp(OMe)-FM
Z-VAD(OMe)-FMK is a pan-caspase inhibitor with irreversible properties; Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C terminal hydrolase L1 (UCHL1), which is irreversibly modified by targeting the UCHL1 active site.
价 格:¥电议型 号:T6013产 地:中国大陆
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T6005Z-DEVD-FMK;化合物Z-DEVD-FMKCaspase-3 Inhibitor;Caspase-3 Inhibitor
Z-DEVD-FMK (Caspase-3 Inhibitor) is a Caspase-3 inhibitor (IC50=18 μM) that is selective, irreversible, and cell-permeable. Z-DEVD-FMK inhibits apoptosis induced by caspase activation.
价 格:¥电议型 号:T6005产 地:中国大陆
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T5954Methyldopa hydrate;L-甲基多巴Alpha-Methyldopa Sesquihydrate|||L-(-)-α-Methyldopa hydrate|||MK-351 hydrat
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
价 格:¥电议型 号:T5954产 地:中国大陆
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T5863LIndinavir;茚地那韦MK-639|||L 735 524|||Crixivan;茚地那韦|||MK-639|||L 735 524|||Crixivan
Indinavir (IDV) is an inhibitor of protease that is used as part of highly active antiretroviral therapy for the treatment of HIV/AIDS.
价 格:¥电议型 号:T5863L产 地:中国大陆
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T5863Indinavir sulfate;硫酸茚地那韦L735524 sulfate|||MK-639 sulfate;L735524 sulfate|||MK-639 sulfate|||硫酸茚地那韦
Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
价 格:¥电议型 号:T5863产 地:中国大陆
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T5836Eprinomectin依普菌素依普菌素|||MK-397
Eprinomectin (MK-397) is an avermectin with anthelmintic and insecticidal activities.
价 格:¥电议型 号:T5836产 地:中国大陆
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T5632Suvecaltamide;化合物MK-8998MK-8998;MK-8998
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.
价 格:¥电议型 号:T5632产 地:中国大陆
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T5396Letermovir;莱莫维韦AIC246|||MK-8828;AIC246|||MK-8828|||莱莫维韦
Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.
价 格:¥电议型 号:T5396产 地:中国大陆
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T5152MKT-077;化合物MKT-077MKT 077|||FJ-776|||MKT077;MKT 077|||FJ-776|||MKT077
MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines (EC50s: 1.4-2.2 μM in vitro) through its ability to inhibit members of the Hsp70 family of molecular chaperones.
价 格:¥电议型 号:T5152产 地:中国大陆
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T5099Gefapixant;化合物GefapixantRO 4926219|||AF219|||MK-7264;RO 4926219|||AF219|||MK-7264
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
价 格:¥电议型 号:T5099产 地:中国大陆
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T4999Ertugliflozin;埃格列净MK-8835|||PF-04971729;埃格列净|||MK-8835|||PF-04971729
PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
价 格:¥电议型 号:T4999产 地:中国大陆
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T4991Ertapenem sodium;厄他培南钠MK-826|||L-749345;厄他培南钠|||MK-826|||L-749345|||尔他培南钠
Ertapenem sodium (MK-826) is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases.
价 格:¥电议型 号:T4991产 地:中国大陆
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T4598BMS-5;化合物BMS5BMS5|||LIMKi 3;BMS5|||LIMKi 3
BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.
价 格:¥电议型 号:T4598产 地:中国大陆
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T4547Grazoprevir;化合物GrazoprevirMK-5172;MK-5172
Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.
价 格:¥电议型 号:T4547产 地:中国大陆
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T4544Elbasvir;化合物ElbasvirMK-8742;MK-8742
Elbasvir (MK-8742) is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) being developed as a component of treatment regimens for chronic HCV infection.
价 格:¥电议型 号:T4544产 地:中国大陆
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T4442MK2-IN-1 hydrochloride;化合物MK2-IN-1 hydrochlorideMK2 Inhibitor|||MK 25;MK2 Inhibitor|||MK 25
MK2-IN-1 hydrochloride (MK 25) is a highly selective, non-ATP competitive inhibitor of p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2, IC50: 0.11 μM) [1].
价 格:¥电议型 号:T4442产 地:中国大陆