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T71586Z-VAE(OMe)-fmk;化合物 Z-VAE(OMe)-fmkZ-VAE(OMe)-fmk
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin´s C-terminal tail, thereby occupying the P1´ (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.
价 格:¥电议型 号:T71586产 地:中国大陆
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T71566MK-7445;化合物 MK-7445MK-7445
MK-7445 is a conformationally constrained inhibitor of non-nucleoside reverse transcriptase.
价 格:¥电议型 号:T71566产 地:中国大陆
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T71556MK-1496;化合物 MK-1496MK-1496
MK1496 is a n orally bioavailable Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor MK1496 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a n
价 格:¥电议型 号:T71556产 地:中国大陆
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T71309MK-886 sodium salt;化合物 MK-886 sodium saltMK-886 sodium salt
MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.
价 格:¥电议型 号:T71309产 地:中国大陆
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T7130Navarixin;化合物NavarixinMK-7123|||SCH 527123;MK-7123|||SCH 527123
Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia.
价 格:¥电议型 号:T7130产 地:中国大陆
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T71276MK-2748;化合物 MK-2748MK-2748
MK-2748 is an inhibitor of NS3 protease, hepatitis C virus.
价 格:¥电议型 号:T71276产 地:中国大陆
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T71165MK-1421;化合物 MK-1421MK-1421
MK-1421 is a potent and selective sstr3 antagonist.
价 格:¥电议型 号:T71165产 地:中国大陆
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T7112Ibutamoren Mesylate;伊布莫仑甲磺酸盐MK-0677|||MK-677;MK-0677|||伊布莫仑甲磺酸盐|||MK-677
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
价 格:¥电议型 号:T7112产 地:中国大陆
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T71067MK-1775 hemihydrate;化合物 MK-1775 hemihydrateMK-1775 hemihydrate
MK-1775 hemihydrate is a WEE1 inhibitor with potential antineoplastic sensitizing activity.
价 格:¥电议型 号:T71067产 地:中国大陆
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T70952UR-MK299;化合物 UR-MK299UR-MK299
UR-MK299 is a NPY Y1 receptor antagonist.
价 格:¥电议型 号:T70952产 地:中国大陆
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T70544MKC-963 (R-isomer);化合物 MKC-963 (R-isomer)MKC-963 (R-isomer)
MKC-963 is a platelet aggregation inhibitor and autoinducer of CYP3A4.
价 格:¥电议型 号:T70544产 地:中国大陆
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T70468MK-8666;化合物 MK-8666MK-8666
MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.
价 格:¥电议型 号:T70468产 地:中国大陆
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T7020Z-VAD-FMK;化合物Z-VAD(OH)-FMKZ-VAD(OH)-FMK|||Caspase Inhibitor VI|||Z-VAD;Z-VAD(OH)-FMK|||Caspase Inhib
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not inhibit UCHL1 activity, even at concentrations up to 440 μM.
价 格:¥电议型 号:T7020产 地:中国大陆
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T7019Z-IETD-FMK;化合物Z-IETD-FMKZ-IE(OMe)TD(OMe)-FMK|||Caspase-8 Inhibitor;Z-IE(OMe)TD(OMe)-FMK|||Caspase-8
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.
价 格:¥电议型 号:T7019产 地:中国大陆
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T7013Vorapaxar;沃拉帕沙SCH 530348|||MK-5348;SCH 530348|||MK-5348|||沃拉帕沙
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).
价 格:¥电议型 号:T7013产 地:中国大陆
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T7011Verubecestat;维罗司他MK-8931;MK-8931|||维罗司他
Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.
价 格:¥电议型 号:T7011产 地:中国大陆
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T69953MK-8666 Tris;化合物 MK-8666 TrisMK-8666 Tris
MK-8666 Tris is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 Tris has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.
价 格:¥电议型 号:T69953产 地:中国大陆
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T69672MK-825;化合物 MK-825MK-825
MK-825 is a cholesteryl ester transfer protein (CETP) inhibitor.
价 格:¥电议型 号:T69672产 地:中国大陆