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T64190Keap1-Nrf2-IN-12；化合物 Keap1-Nrf2-IN-12Keap1-Nrf2-IN-12
eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.
价 格：￥电议型 号：T64190产 地：中国大陆
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T63987Keap1-Nrf2-IN-14；化合物 Keap1-Nrf2-IN-14Keap1-Nrf2-IN-14
Keap1-Nrf2-IN-14 is a KEAP1-NRF2 inhibitor that effectively disrupts the KEAP1-NRF2 interaction (IC50: 75 nM) with a Kd=24 nM for KEAP1. Keap1-Nrf2-IN-14 induces the expression of NRF2 target genes and is able to enhance downstream antioxidant and anti-inflammatory effects. -Nrf2-IN-14 can be used to study oxidative stress-related inflammation.
价 格：￥电议型 号：T63987产 地：中国大陆
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T63622RF9 hydrochloride；化合物 RF9 hydrochlorideRF9 hydrochloride
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).
价 格：￥电议型 号：T63622产 地：中国大陆
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T63364Nrf2 activator-5；化合物 Nrf2 activator-5Nrf2 activator-5
Nrf2 activator-5 is a potent activator of Nrf2 that attenuates H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglia, exhibiting antioxidant and anti-inflammatory activity.
价 格：￥电议型 号：T63364产 地：中国大陆
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T63294Keap1-Nrf2-IN-5；化合物 Keap1-Nrf2-IN-5Keap1-Nrf2-IN-5
Keap1-Nrf2-IN-5 is a potent inhibitor of Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) (IC50: 4.1 μM, Kd: 3.7 μM).
价 格：￥电议型 号：T63294产 地：中国大陆
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T63016Nrf2 activator-4；Nrf2 激活剂4Nrf2 activator-4
Nrf2 activator-4 is an Nrf2 activator that inhibits the production of reactive oxygen species in microglia for the treatment of fatty liver disease associated with metabolic dysfunction in humans.
价 格：￥电议型 号：T63016产 地：中国大陆
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T62654Fluocortin butyl ester；化合物 Fluocortin butyl esterFluocortin butyl ester
Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when used topically. fluocortin butyl ester appears to be an effective, well-tolerated topical steroid that can be used in studies of perennial rhinitis.
价 格：￥电议型 号：T62654产 地：中国大陆
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T61773Keap1-Nrf2-IN-4；化合物 Keap1-Nrf2-IN-4Keap1-Nrf2-IN-4
Keap1-Nrf2-IN-4, a powerful neddylation inhibitor, demonstrates significant anti-proliferation activity against MGC-803 cells (IC50 = 2.55 μM), effectively impeding their migration and inducing apoptosis. Additionally, it effectively inhibits tumor growth while exhibiting minimal toxicity [1].
价 格：￥电议型 号：T61773产 地：中国大陆
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T61688Nrf2 activator-2；化合物 Nrf2 activator-2Nrf2 activator-2
Nrf2 activator-2 (referred to as compound O15), an Osthole derivative, is a highly potent Nrf2 agonist exhibiting an EC 50 of 2.9 μM in 293 T cells. By effectively disrupting the binding between Keap1 and Nrf2, Nrf2 activator-2 activates the Nrf2 pathway. Furthermore, this compound significantly reduces the ubiquitination of Nrf2 in cells, indicating its potential in regulating Nrf2 activity [1].
价 格：￥电议型 号：T61688产 地：中国大陆
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T61522Nrf2/HO-1 activator 2；化合物 Nrf2/HO-1 activator 2Nrf2/HO-1 activator 2
Nrf2/HO-1 activator 2 (compound 13m), a difluoro-substituted derivative, is a highly potent activator of Nrf2/HO-1. It exhibits substantial neuroprotective and antioxidant properties by activating the Nrf2/HO-1 pathway through phosphorylation of ERK1/2, JNK, or Akt in PC12 cells. This compound finds utility in the investigation of Parkinson´s disease (PD) [1].
价 格：￥电议型 号：T61522产 地：中国大陆
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T61205Nrf2/HO-1 activator 1；化合物 Nrf2/HO-1 activator 1Nrf2/HO-1 activator 1
Nrf2/HO-1 activator 1 (Compound 24) is a potent neuroprotective agent with significant antioxidant activities, specifically targeting Nrf2/HO-1. It is particularly useful in Parkinson´s disease (PD) research, illustrating its potential in therapeutic applications [1].
价 格：￥电议型 号：T61205产 地：中国大陆
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T60395Nrf2-ARE/hMAO-B/QR2 modulator 1；化合物 Nrf2-ARE/hMAO-B/QR2 modulator 1Nrf2-ARE/hMAO-B/QR2 modulator 1
Nrf2-ARE/hMAO-B/QR2 modulator 1 is a new resveratrol-based multitarget-directed ligands (MTDLs) that showed a well-balanced MTDL profile: cellular activation of the NRF2-ARE pathway (CD = 9.83 μM), selective inhibition of both hMAO-B and QR2 (IC50s = 8.05 and 0.57 μM), and the best ability to promote hippocampal neurogenesis. Nrf2-ARE/hMAO-B/QR2 modulator 1 exerts neuroprotective and antioxidant actions in both acute and chronic Alzheimer models using hippocampal tissues.
价 格：￥电议型 号：T60395产 地：中国大陆
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T5853Rubitecan；鲁比特康RFS 2000|||9-Nitrocamptothecin；RFS 2000|||鲁比特康|||9-Nitrocamptothecin
Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.
价 格：￥电议型 号：T5853产 地：中国大陆
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T5571Forchlorfenuron；氯吡脲Forchlorfenuron (KT-30, CPPU)；氯苯吡脲|||氯吡脲|||Forchlorfenuron (KT-30, CPPU)
Forchlorfenuron (Forchlorfenuron (KT-30, CPPU)) is plant growth regulator and cytokinin; can be used to increase fruit size of fruits.
价 格：￥电议型 号：T5571产 地：中国大陆
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T5027Dimemorfan phosphate；二甲啡烷磷酸盐3,17-dimethylmorphinan；二甲啡烷磷酸盐|||3,17-dimethylmorphinan
Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a potent antitussive.
价 格：￥电议型 号：T5027产 地：中国大陆
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T4638E260；化合物Fer and FerT inhibitorFer and FerT inhibitor；Fer and FerT inhibitor
E260 (Fer and FerT inhibitor) is a Fer/FerT kinase inhibitor
价 格：￥电议型 号：T4638产 地：中国大陆
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T40685L26RFa Acetate (mouse,rat)；26RFa 醋酸（大鼠，小鼠）Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (6001
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (Orphan GPCR SP9155 agonist P550 ) is a member of the RFamide peptide family with orexigenic effects.
价 格：￥电议型 号：T40685L产 地：中国大陆
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T40685Orphan GPCR SP9155 agonist P550 (mouse, rat)；Orphan GPCR SP9155 agonist P550 (mouse, rat)26RFa (mous
Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)) is an orphan GPCR with an orexigenic effect belonging to the RFamide peptide family. It acts as the cognate ligand for the mouse orphan receptor GPR103, which is also known as SP9155 or AQ27.
价 格：￥电议型 号：T40685产 地：中国大陆
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T40588Acifluorfen；三氟羧草醚Acifluorfen
Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX) and induces tumors in rodent livers. It causes significant photooxidative damage to pigments and lipids in sensitive plant species.
价 格：￥电议型 号：T40588产 地：中国大陆
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T40398Crinecerfont hydrochloride；Crinecerfont hydrochlorideSSR-125543A|||SSR-125543 hydrochloride；SSR-1255
Crinecerfont hydrochloride (SSR-125543) is a highly potent, orally active, non-peptide antagonist of the CRF1 receptor. It has demonstrated efficacy in the context of Classic congenital adrenal hyperplasia (CAH) research.
价 格：￥电议型 号：T40398产 地：中国大陆
