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T18018HS-27;化合物HS-27HS-27
HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC. HS-27 can be used in see-and-treat paradigms.
价 格:¥电议型 号:T18018产 地:中国大陆
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T1730NPS-2143;化合物NPS 2143SB262470|||NPS 2143|||SB 262470A;SB262470|||NPS 2143|||SB 262470A|||2-氯-6-[(2R)-
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
价 格:¥电议型 号:T1730产 地:中国大陆
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T17277YS-201;化合物 T17277YS-201
YS-201 is an antagonist of dihydropyridine-type calcium channel.
价 格:¥电议型 号:T17277产 地:中国大陆
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T17165Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine化合物 T17165tris-2-tert-butoxycarbonyl-ethoxy-me
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine, a cleavable PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, specifically Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane, widely used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17165产 地:中国大陆
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T17020TCS 2314;化合物 T17020TCS-2314|||TCS 2314|||TCS 2314|||TCS2314;TCS-2314|||TCS 2314|||TCS 2314|||TCS2314
TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).
价 格:¥电议型 号:T17020产 地:中国大陆
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T16936SS-208;化合物SS-208SS-208
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
价 格:¥电议型 号:T16936产 地:中国大陆
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T16817S-2474;化合物 S-2474S-2474
S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced cell death.
价 格:¥电议型 号:T16817产 地:中国大陆
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T16799RS-246204;化合物 T16799RS-246204
RS-246204 is an R-spondin-1 substitute compound. RS-246204 is able to initiate small intestinal organoids without the use of the R-spondin-1 protein.
价 格:¥电议型 号:T16799产 地:中国大陆
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T16732Reproxalap;化合物ReproxalapNS-2|||ADX-102;NS-2|||ADX-102
Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye.
价 格:¥电议型 号:T16732产 地:中国大陆
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T16344NS-2028;化合物NS-2028NS-2028
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM). NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM). NS
价 格:¥电议型 号:T16344产 地:中国大陆
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T1632Amitraz双甲脒BTS-27419|||NSC 324552|||双甲脒
Amitraz (NSC 324552) is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mange in dogs.
价 格:¥电议型 号:T1632产 地:中国大陆
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T1530Mitiglinide calcium hydrate;米格列奈钙KAD-1229 calcium hydrate|||Mitiglinide calcium|||S-21403 calcium hy
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda.
价 格:¥电议型 号:T1530产 地:中国大陆
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T15286Flindokalner;化合物FlindokalnerBMS-204352;BMS-204352
Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner displays a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM) and acts as a negative modulator of GABAA receptors and it also shows anxiolytic efficacy in vivo.
价 格:¥电议型 号:T15286产 地:中国大陆
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T14690BMS 433796;化合物BMS 433796BMS-289948|||BMS-299897;BMS-289948|||BMS-299897
BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T14690产 地:中国大陆
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T14672BMS-248360;化合物 T14672BMS-248360
BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor. With Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 shows hypertensive effects[1].
价 格:¥电议型 号:T14672产 地:中国大陆
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T1445Agomelatine;阿戈美拉汀Thymanax|||S-20098|||Valdoxan;Thymanax|||S-20098|||Valdoxan|||阿戈美拉汀
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
价 格:¥电议型 号:T1445产 地:中国大陆
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T14380AZD7507;化合物CS-2850AZD7507
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
价 格:¥电议型 号:T14380产 地:中国大陆
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T13748L-2-Hydroxyglutaric acid disodium;S-2-羟基戊二酸(S)-2-Hydroxyglutaric acid disodium;S-2-羟基戊二酸|||(S)-2-Hyd
L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively).
价 格:¥电议型 号:T13748产 地:中国大陆
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T1293Gatifloxacin;加替沙星BMS 206584-01|||PD 135432|||CG5501|||BMS-206584|||AM-1155;BMS 206584-01|||PD 135432
Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
价 格:¥电议型 号:T1293产 地:中国大陆
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T125980ES-242-4;化合物 ES-242-4ES-242-4
ES-242-4 is a useful organic compound for research related to life sciences. The catalog number is T125980 and the CAS number is 136565-69-0.
价 格:¥电议型 号:T125980产 地:中国大陆