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T16936SS-208;化合物SS-208SS-208
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
价 格:¥电议型 号:T16936产 地:中国大陆
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T16934SRX246;化合物 T16934SRX246
SRX246 has no interaction at V1b and V2 receptors. SRX246 shows negligible binding at 64 other receptors classes, including 35 G-proteincoupled receptors. SRX246 is a potent and CNS-penetrant vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a).
价 格:¥电议型 号:T16934产 地:中国大陆
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T16932SRT 2183;化合物SRT 2183SRT 2183
SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM).
价 格:¥电议型 号:T16932产 地:中国大陆
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T16930SR9238;化合物SR9238SR9238
SR9238 is a synthetic agonist of liver X receptor inverse (IC50s: 214 nM and 43 nM for LXRα and LXRβ, respectively).
价 格:¥电议型 号:T16930产 地:中国大陆
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T1693Umbelliferone;7-羟基香豆素Skimmetine|||Hydrangin|||Hydrangine|||7-Hydroxycoumarin|||NSC 19790;Skimmetine|
Umbelliferone (7-Hydroxycoumarin) is found in anise. Umbelliferone occurs widely in plants including Angelica species Phytoalexin of infected sweet potat. It has been reported to have antioxidant properties.
价 格:¥电议型 号:T1693产 地:中国大陆
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T16893SKF-82958;化合物 T16893Chloro-AP|||(±)-SKF 82958;Chloro-AP|||(±)-SKF 82958
SKF 82958 is a D1/D5 receptor full agonist.
价 格:¥电议型 号:T16893产 地:中国大陆
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T16794RO 4938581;化合物 T16794RO 4938581
RO 4938581 is an effective and selective agonist of GABAA α5 inverse (Ki: 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively)).
价 格:¥电议型 号:T16794产 地:中国大陆
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T16793RO-28-1675;化合物 T16793Ro 28-1675;Ro 28-1675
Ro 28-1675 is an effective allosteric GK activator (IC50: 0.24± 0.0019 uM).
价 格:¥电议型 号:T16793产 地:中国大陆
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T16717Radequinil;化合物 T16717AC-3933;AC-3933
Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).
价 格:¥电议型 号:T16717产 地:中国大陆
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T16704LQuilseconazole Formic acid(1340593-70-5 Free base);化合物 Quilseconazole Formic acid(1340593-70-5 Free
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
价 格:¥电议型 号:T16704L产 地:中国大陆
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T16693Pyrene-PEG5-alcohol;化合物 T16693Pyrene-PEG5-alcohol
Pyrene-PEG5-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16693产 地:中国大陆
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T16593Propargyl-PEG10-acid;化合物 T16593Propargyl-PEG10-acid
Propargyl-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16593产 地:中国大陆
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T16576Pritelivir mesylate化合物 T16576BAY 57-1293 mesylate|||AIC316 mesylate
Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate shows antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection.
价 格:¥电议型 号:T16576产 地:中国大陆
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T16575Pritelivir mesylate hydrate化合物 T16575BAY 57-1293 mesylate hydrate|||AIC316 mesylate hydrate
Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate hydrate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate hydrate shows antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection.
价 格:¥电议型 号:T16575产 地:中国大陆
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T16504PF-4693627;化合物 T16504PF-4693627
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA).
价 格:¥电议型 号:T16504产 地:中国大陆
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T16493PF-06465469;化合物 T16493PF-06465469
PF-06465469 is a covalent ITK inhibitor(IC50: 2 nM).
价 格:¥电议型 号:T16493产 地:中国大陆
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T16479PF-04937319;化合物PF-04937319PF-04937319
PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T16479产 地:中国大陆
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T16393ONO-2952;化合物 T16393ONO-2952
ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. ONO-2952 is a potent and selective translocator protein 18 kDa (TSPO) antagonist (Ki: 0.33-9.30 nM for rat and human TSPO). ONO-2952 has the potential for irritable bowel syndrome treatment. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of the noradrenergic system in the brain without the amnesic effect.
价 格:¥电议型 号:T16393产 地:中国大陆
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T16293NGD-4715;化合物 T16293NGD-4715
NGD-4715 is a selective and orally active antagonist of melanin-concentrating hormone receptor 1.
价 格:¥电议型 号:T16293产 地:中国大陆