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T15593IQ-R;化合物 T15593IQ-R
IQ-R is a novel hypoxia-sensitive fluorescent probe that consists of an indolequinone unit coupled with a rhodol fluorophore.
价 格:¥电议型 号:T15593产 地:中国大陆
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T15558GSK319347A;化合物GSK319347AGSK319347A
GSK319347A is a selective and potent dual inhibitor of TBK1 and IKKε with potential anti-tumor activity and inhibition of IKK2 activity, which can be used in the study of bladder cancer and lung adenocarcinoma.
价 格:¥电议型 号:T15558产 地:中国大陆
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T15505HSK0935;化合物 T15505HSK 0935|||HSK-0935;HSK 0935|||HSK-0935
HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.
价 格:¥电议型 号:T15505产 地:中国大陆
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T15493HO-PEG21-OH;化合物 T15493HO-PEG21-OH
HO-PEG21-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15493产 地:中国大陆
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T15438GSK3186899;化合物GSK31868993,3,3-trifluoro-N-[4-[[3-[(2R)-2-methylmorpholin-4-yl]-1H-pyrazolo[3,4-d]pyr
GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.
价 格:¥电议型 号:T15438产 地:中国大陆
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T15425GSK1702934A;化合物 T15425GSK1702934A
GSK1702934A is a selective TRPC3 agonist. It modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3.
价 格:¥电议型 号:T15425产 地:中国大陆
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T15393Glycerol phenylbutyrate;苯丁酸甘油酯HPN-100;苯丁酸甘油酯|||HPN-100
Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
价 格:¥电议型 号:T15393产 地:中国大陆
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T15344Minocromil;米诺罗米FPL59360;米诺罗米|||FPL59360
Minocromil is a new agent of Anti-asthmatic.
价 格:¥电议型 号:T15344产 地:中国大陆
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T15293Fluorescein-PEG4-acid;化合物 T15293Fluorescein-PEG4-acid
Fluorescein-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15293产 地:中国大陆
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T15276Ferroquine;二茂铁氯喹SSR97193|||Ferrochloroquine;SSR97193|||Ferrochloroquine
Ferroquine (Ferrochloroquine) is a ferrocenyl analogue of Chloroquine with antimalarial activity. Ferroquine induces oxidative stress and the subsequent destruction of the membrane, resulting in parasiticidal effect on Plasmodium.
价 格:¥电议型 号:T15276产 地:中国大陆
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T15241ER-000444793;化合物ER-000444793ER-000444793
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
价 格:¥电议型 号:T15241产 地:中国大陆
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T15239Epristeride;爱普列特SKF105657|||ONO-9302;SKF105657|||ONO-9302
Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Episteride induces atrophy and apoptosis of the ventral prostate in rats.
价 格:¥电议型 号:T15239产 地:中国大陆
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T15193EBI-1051;化合物 T15193EBI-1051
EBI-1051 is a highly potent and orally efficacious inhibitor of MEK (IC50: 3.9 nM).
价 格:¥电议型 号:T15193产 地:中国大陆
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T15165DPI-3290;化合物 T15165Org 41793;Org 41793
DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively) with potent antinociceptive activity. DPI-3290 is one of a series of novel centrally acting agents.
价 格:¥电议型 号:T15165产 地:中国大陆
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T15163DPC-681;化合物 T15163DPH-153893;DPH-153893
DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1).
价 格:¥电议型 号:T15163产 地:中国大陆
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T15093Dehydro-ZINC39395747;化合物 T15093Dehydro-ZINC39395747
Dehydro-ZINC39395747 is a ZINC39395747 derivative. ZINC39395747 can increase NO bioavailability in vascular cells. ZINC39395747 is a potent cytochrome b5 reductase 3 inhibitor (IC50 : 9.14 μM and Kd: 1.11 μM).
价 格:¥电议型 号:T15093产 地:中国大陆
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T15088Debio 0932;化合物 T15088CUDC-305;CUDC-305
Debio 0932 is an orally active inhibitor of HSP90 (IC50s: 100 and 103 nM for HSP90α and HSP90β, respectively).
价 格:¥电议型 号:T15088产 地:中国大陆
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T14993Rociletinib hydrobromide;化合物 T14993AVL-301 hydrobromide|||CO-1686 (hydrobromide)|||CNX-419 hydrobrom
Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).
价 格:¥电议型 号:T14993产 地:中国大陆
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T14949Chloramben化合物 T149493-Amino-2,5-dichlorobenzoic acid
Chloramben, a herbicide, is used to control the seedlings of annual grasses and broadleaf weeds.
价 格:¥电议型 号:T14949产 地:中国大陆
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T14945CH-0793076;化合物 T14945TP3076;TP3076
CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 μM).
价 格:¥电议型 号:T14945产 地:中国大陆