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T14593Biotin-PEG3-Mal;化合物 T14593Biotin-PEG3-Mal
Biotin-PEG3-Mal is a biotinylated polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs). By introducing the biotin moiety, it enables specific recognition and binding to target proteins. Additionally, the PEG spacer contributes to improved solubility and flexibility of the linker. This compound offers a valuable tool for constructing PROTACs, which hold great potential in targeted protein degradation strategies[1].
价 格:¥电议型 号:T14593产 地:中国大陆
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T14557BI-1935;化合物BI-1935BI-1935
BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease.
价 格:¥电议型 号:T14557产 地:中国大陆
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T14524Befetupitant;贝非匹坦Ro67-5930;Ro67-5930
Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.
价 格:¥电议型 号:T14524产 地:中国大陆
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T14493Balapiravir化合物 T14493R1626|||Ro 4588161
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (most often for lymphopenia) and the percentage of patients with serious adverse events (especially hematological, infection, ocular events) was dose related. Balapiravir (R1626) is the tri-isobutyrate ester prodrug of R1479 under clinical develop
价 格:¥电议型 号:T14493产 地:中国大陆
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T14393Azide-PEG3-C1-Ala;化合物 T14393Azide-PEG3-C1-Ala
Azide-PEG3-C1-Ala is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14393产 地:中国大陆
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T14293Annonacin;化合物 T14293Annonacin
Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex and it is the active agent found in Graviola leaf extract to act as an inhibitor of sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps[1].
价 格:¥电议型 号:T14293产 地:中国大陆
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T14198ALX-1393;化合物ALX-1393ALX-1393
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain.
价 格:¥电议型 号:T14198产 地:中国大陆
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T14193α-Galactosylceramide;化合物KRN7000KRN7000|||α-GalCer;KRN7000|||α-GalCer
α-Galactosylceramide (KRN7000) is a synthetic glycolipid with antitumorial and immunostimulatory and is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide and CD1d can bind to the T cell antigen receptor of NKT cells.
价 格:¥电议型 号:T14193产 地:中国大陆
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T1419Azithromycin hydrate;阿奇霉素二水合物CP-62993 dihydrate|||Azithromycin dihydrate;CP-62993 dihydrate|||阿奇霉素二水
Azithromycin hydrate (CP-62993 dihydrate) is a semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
价 格:¥电议型 号:T1419产 地:中国大陆
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T14139Aganepag;化合物 T14139AGN 210937;AGN 210937
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, scar reduction, scar prevention, and the treatment and prevention of wrinkles.
价 格:¥电议型 号:T14139产 地:中国大陆
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T14093Ac4ManNAz;化合物Ac4ManNAzAc4ManNAz
Ac4ManNAz is an azido-containing metabolic glycoprotein labeling reagent. It can be used to selectively modify proteins, and it can be used in cell labeling, tracking and proteomic analysis;
价 格:¥电议型 号:T14093产 地:中国大陆
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T14077A-935142;化合物A-935142A-935142
A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. a-935142 enhances hERG currents by slowing inactivation, promoting activation, reducing inactivation, shortening atrial and ventricular repolarization, and in a complex manner.
价 格:¥电议型 号:T14077产 地:中国大陆
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T140293,6-Dioxaoctanedioic acid;化合物 T140293,6-Dioxaoctanedioic acid
3,6-dioxaoctanedioic acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].
价 格:¥电议型 号:T14029产 地:中国大陆
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T139931-Isothiocyanato-PEG3-azide;化合物 T139931-Isothiocyanato-PEG3-azide
1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker utilized for PROTAC synthesis[1].
价 格:¥电议型 号:T13993产 地:中国大陆
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T13939Tubulysin E;微管蛋白抑制剂 ETubulysin E
Tubulysin E is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide.
价 格:¥电议型 号:T13939产 地:中国大陆
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T13937Tubulysin B;化合物 T13937Tubulysin B
Tubulysin B is an agent of potent microtubule destabilizing and highly cytotoxic peptide isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis.
价 格:¥电议型 号:T13937产 地:中国大陆
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T13936Triptotriterpenic acid A;化合物 T13936Maytenfolic acid|||Abrusgenic acid;Maytenfolic acid|||Abrusgenic
Triptotriterpenic acid A is a natural product isolate from Tripterygium wilfordii.
价 格:¥电议型 号:T13936产 地:中国大陆
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T13935(+)-trans-Isolimonene;化合物 T13935(+)-trans-Isolimonene
(+)-trans-Isolimonene is a natural product (monoterpene) isolated from essential oil.
价 格:¥电议型 号:T13935产 地:中国大陆
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T13934Toxicarol isoflavone;化合物 T13934Toxicarol isoflavone
Toxicarol isoflavone, an iso avone, is extracted from Millettia brandisiana.
价 格:¥电议型 号:T13934产 地:中国大陆
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T13933Toringin;三叶海棠素Toringin
Toringin is a bioflavonoid isolated from the bark of Docyniopsis tschonoski, and have various biological activities and beneficial actions against cancers, coronary heart disease, among other pathologies.
价 格:¥电议型 号:T13933产 地:中国大陆