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  • T68143Solpecainol；索培卡诺Solpecainol

    solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.

    价 格：￥电议型 号：T68143产 地：中国大陆

  • T67844RBN-3143；化合物RBN-3143RBN-3143

    RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines. RBN-3143 exhibits research potential of lung inflammation.

    价 格：￥电议型 号：T67844产 地：中国大陆

  • T6763Xevinapant；化合物AT406ARRY-334543|||SM-406|||AT406|||Debio-1143；ARRY-334543|||SM-406|||AT406|||Debio-11

    Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.

    价 格：￥电议型 号：T6763产 地：中国大陆

  • T671431-Naphthalenemethanol；化合物 1-Naphthalenemethanol1-Naphthalenemethanol

    1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.

    价 格：￥电议型 号：T67143产 地：中国大陆

  • T66143rac-Boc-β2-homophenylalanine；化合物 rac-Boc-β2-homophenylalaninerac-Boc-β2-homophenylalanine

    rac-Boc-β2-homophenylalanine is a useful organic compound for research related to life sciences. The catalog number is T66143 and the CAS number is 26250-90-8.

    价 格：￥电议型 号：T66143产 地：中国大陆

  • T65143Tetraxetan；化合物 2,2’,2’’,2’’’-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acidTetrax

    Tetraxetan is a useful organic compound for research related to life sciences. The catalog number is T65143 and the CAS number is 60239-18-1.

    价 格：￥电议型 号：T65143产 地：中国大陆

  • T6422Brimonidine Tartrate；酒石酸溴莫尼定AGN190342 tartrate|||304 tartrate|||AGN190342 (tartrate)|||UK 14304 (tar

    Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hypertension.

    价 格：￥电议型 号：T6422产 地：中国大陆

  • T64143AChE/GSK-3β-IN-1；化合物 AChE/GSK-3β-IN-1AChE/GSK-3β-IN-1

    AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-3β (IC50: 22.4 nM). AChE/GSK-3β-IN-1 is able to occupy the ATP binding site of DYRK1A. aChE/GSK-3β-IN-1 exhibits high kinase selectivity for the CMGC kinase family. aChE/GSK-3β-IN-1 inhibits ROS expression and reduces oxidative stress. aChE/GSK-3β-IN-1 can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T64143产 地：中国大陆

  • T6339AG14361；化合物AG14361AG 14361|||AG-14361；AG 14361|||AG-14361

    AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).

    价 格：￥电议型 号：T6339产 地：中国大陆

  • T63143DENV-IN-5；化合物DENV-IN-5DENV-IN-5

    Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.

    价 格：￥电议型 号：T63143产 地：中国大陆

  • T62143LP-922761 hydrate；化合物 LP-922761 hydrateLP-922761 hydrate

    LP-922761 hydrate is a selective, potent, orally active AAK1 inhibitor with IC50 values of 4.8 nM and 7.6 nM in enzyme and cellular assays, respectively. LP-922761 hydrate inhibits BMP-2 inducible protein kinase (BIKE) (IC50: 24 nM). 922761 hydrate has no significant effect on cellular GAK, opioids, adrenergic α2 or GABAa receptors.

    价 格：￥电议型 号：T62143产 地：中国大陆

  • T6143LPI-103 Hydrochloride；化合物 T6143LPI-103 Hydrochloride

    PI-103 Hydrochloride is a potent dual inhibitor of PI3K and mTOR, demonstrating inhibitory IC50 values of 8 nM for p110α, 88 nM for p110β, 48 nM for p110δ, 150 nM for p110γ, 20 nM for mTORC1, and 83 nM for mTORC2, respectively. Additionally, it inhibits DNA-PK with an IC50 of 2 nM and induces autophagy [1] [2] [3] [4].

    价 格：￥电议型 号：T6143L产 地：中国大陆

  • T61439DSS30；化合物DSS30DSS30

    DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl), which reduces the secretion of β-amyloid (Aβ).DSS30 can be used for the prevention and treatment of neurodegenerative diseases such as Alzheimer´s disease.

    价 格：￥电议型 号：T61439产 地：中国大陆

  • T61438Propiverine；化合物 PropiverinePropiverine

    Propiverine is a potent antimuscarinic agent that effectively inhibits cellular calcium influx, leading to the reduction of muscle spasm. It exhibits neurotropic and musculotropic effects specifically on the smooth muscles of the urinary bladder. Propiverine proves valuable in research concerning overactive bladder (OAB) [1] [2].

    价 格：￥电议型 号：T61438产 地：中国大陆

  • T61437HPK1-IN-26；化合物 HPK1-IN-26HPK1-IN-26

    HPK1-IN-26, a novel compound, is a potent inhibitor of both HPK1 and GLK. This small molecule exhibits promise in aiding the study of animal pathogen infection [1].

    价 格：￥电议型 号：T61437产 地：中国大陆

  • T61436Cdc7-IN-18；化合物 Cdc7-IN-18Cdc7-IN-18

    Cdc7-IN-18 (compound 1-2) is a highly effective inhibitor of the CDC7 enzyme. It has an IC 50 value of 1.29 nM for the Cdc7/DBF4 enzyme. In addition, this compound exhibits strong antiproliferative activities, with an IC 50 value of 53.62 nM in COLO205 cells [1].

    价 格：￥电议型 号：T61436产 地：中国大陆

  • T61435(S)-Cdc7-IN-18；化合物 (S)-Cdc7-IN-18(S)-Cdc7-IN-18

    (S)-Cdc7-IN-18, a potent CDC7 inhibitor, effectively impedes the overactivation of MCM2, a crucial tumor cell marker, induced by huCdc7 overexpression. Consequently, it inhibits the aberrant proliferation of tumor cells. This compound, exhibits promise for cancer disease research [1].

    价 格：￥电议型 号：T61435产 地：中国大陆

  • T61434Mirogabalin besylate；化合物 Mirogabalin besylateMirogabalin besylate

    Mirogabalin besylate is a potent and orally active ligand that selectively targets the α2δ subunit of voltage-gated calcium channels. It displays high affinity (K d ) values, namely 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM, for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively.

    价 格：￥电议型 号：T61434产 地：中国大陆

  • T61433HDAC1-IN-5；化合物 HDAC1-IN-5HDAC1-IN-5

    HDAC1-IN-5, a potent inhibitor of HDAC1 with an IC50 value of 15 nM, also exhibits inhibitory activity towards HDAC6 with an IC50 value of 20 nM. In cancer cells, HDAC1-IN-5 enhances the acetylation of both histone H3 and α-tubulin, leading to the activation of caspase 3 and induction of apoptosis. Additionally, HDAC1-IN-5 binds with DNA, causing chromatin damage. Furthermore, it demonstrated strong inhibitory activity against tumor growth in xenograft mice. [1]

    价 格：￥电议型 号：T61433产 地：中国大陆

  • T61432ATR-IN-16；化合物 ATR-IN-16ATR-IN-16

    ATR-IN-16 (compound 46) is a highly effective ATR kinase inhibitor, exhibiting considerable anticancer activity in LoVo cells, as demonstrated by its IC 50 value of 410 nM [1].

    价 格：￥电议型 号：T61432产 地：中国大陆

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