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T14371AZD1152AZD1152,Barasertib,
AZD1152 is a pro-drug of Barasertib-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
价 格：￥电议型 号：T14371产 地：美洲
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T14374AZD2906AZD2906
AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1]. AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats.
价 格：￥电议型 号：T14374产 地：美洲
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T14375AZD3988AZD3988
AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
价 格：￥电议型 号：T14375产 地：美洲
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T14377AZD5423AZD5423
AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM)[1] and it effectively reduces allergen-induced responses in subjects with mild allergic asthma[2].
价 格：￥电议型 号：T14377产 地：美洲
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T14378AZD5582AZD5582
AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs). Which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis[1].
价 格：￥电议型 号：T14378产 地：美洲
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T14379AZD5904AZD5904
AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM. Which has similar potency in mouse and rat.
价 格：￥电议型 号：T14379产 地：美洲
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T1438Butoconazole nitrateButoconazole nitrate,RS 35887,
Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changi
价 格：￥电议型 号：T1438产 地：美洲
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T14380AZD7507AZD7507
AZD7507 is a CSF-1R inhibitor. It has antitumor activity.
价 格：￥电议型 号：T14380产 地：美洲
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T14382AZD7687AZD7687
AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent
价 格：￥电议型 号：T14382产 地：美洲
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T14383AZD8329AZD8329
AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1. Which displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].
价 格：￥电议型 号：T14383产 地：美洲
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T14384AZD8797AZD8797
AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor. For antagonizes CX3CR1 and CXCR2, the Kis values are 3.9 and 2800 nM, respectively.
价 格：￥电议型 号：T14384产 地：美洲
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T14385AZD9056 hydrochlorideAZD9056 hydrochloride
AZD9056 hydrochloride is a P2X7 inhibitor. Which plays a significant role in pain-causing diseases and inflammation.
价 格：￥电议型 号：T14385产 地：美洲
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T14386AZD9567AZD9567
AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. It shows excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].
价 格：￥电议型 号：T14386产 地：美洲
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T1439LacidipineLacidipine,GX-1048,GR-43659X,SN-305,GX-1048
Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specificity in the vascular smooth muscle, where it
价 格：￥电议型 号：T1439产 地：美洲
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T15623JNJ-61432059JNJ-61432059
In mouse hippocampus, Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models. JNJ-61432059 is an oral active and selective negative modu
价 格：￥电议型 号：T15623产 地：美洲
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T16143MRTX-1257MRTX-1257
MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.
价 格：￥电议型 号：T16143产 地：美洲
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T2143BergaptenBergapten,5-Methoxypsoralen,
Bergapten, a psoralen, inhibits cell replication.
价 格：￥电议型 号：T2143产 地：美洲
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T4967NPS-2143 HCLNPS-2143 HCL,NPS-2143 hydrochloride,
NPS-2143 is a selective potent calcium ion-sensing receptor antagonist.
价 格：￥电议型 号：T4967产 地：美洲
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T5174NestoronNestoron,Nestorone,ST-1435
Nestoron, a synthetic progestin, is a high-affinity agonist of the progesterone receptor (EC50: 10.3 nM).
价 格：￥电议型 号：T5174产 地：美洲
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T5353ABX-1431ABX-1431
ABX-1431 is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).
价 格：￥电议型 号：T5353产 地：美洲
