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T14306ApimostinelApimostinel,NRX-1074,AGN-241660
Apimostinel (NRX-1074; AGN-241660) is a partial agonist of NMDA receptor.
价 格:¥电议型 号:T14306产 地:美洲
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T1431KhellinKhellin,Visammin,Amicardine
Khellin is a vasodilator that also has bronchodilatory action.
价 格:¥电议型 号:T1431产 地:美洲
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T14312ApratastatApratastat
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s
价 格:¥电议型 号:T14312产 地:美洲
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T14314ApronalApronal,Allylisopropylacetylurea,Apronalide
Apronal (Allylisopropylacetylurea, Apronalide) is a hypnotic and sedative drug. It has been withdrawn in several countries due to side effects.
价 格:¥电议型 号:T14314产 地:美洲
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T14315AR-9281AR-9281,APAU,
AR9281 is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH). It has potential for the treatment of hypertension and type 2 diabetes[1].
价 格:¥电议型 号:T14315产 地:美洲
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T14316AR-C155858AR-C155858
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
价 格:¥电议型 号:T14316产 地:美洲
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T1432PhenylbutazonePhenylbutazone,Butazolidine,
Phenylbutazone is a butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ankylosing spondylitis, rheumatoid arthritis, and reactive arthritis.
价 格:¥电议型 号:T1432产 地:美洲
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T14320ARL67156 trisodium saltARL67156 trisodium salt
ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12?μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
价 格:¥电议型 号:T14320产 地:美洲
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T14323ARQ 531ARQ 531
ARQ 531 is a reversible non-covalent inhibitor of Bruton’s Tyrosine Kinase (BTK). With IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.
价 格:¥电议型 号:T14323产 地:美洲
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T14324ArtemisoneArtemisone,Artemifone,BAY 44-9585
Artemisone (Artemifone) is a potent and semi-synthetic antimalarial. Which inhibits P. falciparum strains (IC50: 0.83 nM).
价 格:¥电议型 号:T14324产 地:美洲
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T14325ArterolaneArterolane,OZ 277,RBx 11160
Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.
价 格:¥电议型 号:T14325产 地:美洲
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T14327AS1949490AS1949490
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.
价 格:¥电议型 号:T14327产 地:美洲
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T1433Ritodrine hydrochlorideRitodrine hydrochloride,Ritodrine HCl,NSC 291565
Ritodrine binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine is a phenethylamine derivative with tocolytic activity. Specifically, ritodrine
价 格:¥电议型 号:T1433产 地:美洲
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T14331GusacitinibGusacitinib,ASN-002,
Gusacitinib (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
价 格:¥电议型 号:T14331产 地:美洲
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T14332AsoprisnilAsoprisnil,J867,
Asoprisnil (J867) is a selective progesterone receptor modulator. Which exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human[1].
价 格:¥电议型 号:T14332产 地:美洲
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T14334ASP2535ASP2535
ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitive impairment in animal models of schizophrenia and Alzheimer´s disease[1].
价 格:¥电议型 号:T14334产 地:美洲
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T14335ASP6432ASP6432
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.
价 格:¥电议型 号:T14335产 地:美洲
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T14338AtabecestatAtabecestat,JNJ-54861911,
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and
价 格:¥电议型 号:T14338产 地:美洲
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T1434ClarithromycinClarithromycin,A-56268,
Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classification of clarithromycin is Macrolides.
价 格:¥电议型 号:T1434产 地:美洲
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T14341ATN-224ATN-224,Bis(choline)tetrathiomolybdate,
ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor.
价 格:¥电议型 号:T14341产 地:美洲