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T14367AZ1495
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).
价 格:¥电议型 号:T14367产 地:中国大陆
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T14366AZ10606120 dihydrochloride
AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1]. AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM and it is little or no effect at oth
价 格:¥电议型 号:T14366产 地:中国大陆
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T14365AZ PFKFB3 26
AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.
价 格:¥电议型 号:T14365产 地:中国大陆
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T14364AZ-Dyrk1B-333-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
价 格:¥电议型 号:T14364产 地:中国大陆
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T14362AY 9944
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation o
价 格:¥电议型 号:T14362产 地:中国大陆
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T14364-Aminohippuric Acid对氨基马尿酸;p-Aminohippuric acid
Aminohippuric acid is the glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
价 格:¥电议型 号:T1436产 地:中国大陆
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T14358AvoralstatAVORALSTAT;BCX4161
Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
价 格:¥电议型 号:T14358产 地:中国大陆
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T14353Auxinole
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
价 格:¥电议型 号:T14353产 地:中国大陆
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T14350SoblidotinAuristatin PE;TZT-1027
Soblidotin (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.
价 格:¥电议型 号:T14350产 地:中国大陆
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T1435Praziquantel吡喹酮;Droncit;Pyquiton;Biltricide
Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm´s musculature through a subsequent increase in levels of
价 格:¥电议型 号:T1435产 地:中国大陆
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T14349Auristatin F
Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
价 格:¥电议型 号:T14349产 地:中国大陆
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T14348Auristatin E
Auristatin E inhibits cell division by blocking the polymerisation of tubulin. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Auristatin E, an MMAE analog, is cytotoxin in Antibody-drug conjugates.
价 格:¥电议型 号:T14348产 地:中国大陆
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T14346Aumitin
Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1], and it inhibits mitochondrial respiration by targeting complex I.
价 格:¥电议型 号:T14346产 地:中国大陆
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T14345Atropine methyl bromide甲溴阿托品;Methylatropine bromide
Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist. Which is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It penetrates less readily into the central nervous system than atr
价 格:¥电议型 号:T14345产 地:中国大陆
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T14341ATN-224Bis(choline)tetrathiomolybdate;四硫钼酸二胆碱
ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor.
价 格:¥电议型 号:T14341产 地:中国大陆
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T1434ClarithromycinA-56268;克拉霉素
Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classification of clarithromycin is Macrolides.
价 格:¥电议型 号:T1434产 地:中国大陆
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T14336AllitinibAST-1306;ALS 1306
Allitinib (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]
价 格:¥电议型 号:T14336产 地:中国大陆
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T14331GusacitinibASN-002
Gusacitinib (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
价 格:¥电议型 号:T14331产 地:中国大陆
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T1433Ritodrine hydrochlorideDU21220;NSC 291565;Ritodrine HCl;盐酸利托君
Ritodrine binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine is a phenethylamine derivative with tocolytic activity. Specifically, ritodrine
价 格:¥电议型 号:T1433产 地:中国大陆