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T71898Bromotubercidin；化合物 BromotubercidinBromotubercidin
Bromotubercidin is a reversible inhibitor of RNA synthesis. Bromotubercidin is a biochemical.
价 格：￥电议型 号：T71898产 地：中国大陆
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T71897Vatalanib succinate；化合物 Vatalanib succinateVatalanib succinate
Vatalanib succinate is a VEGFR, PDGFR-β, c-Kit, c-Fms, and aromatase inhibitor.
价 格：￥电议型 号：T71897产 地：中国大陆
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T71896Brevicompanine B；化合物 Brevicompanine BBrevicompanine B
Brevicompanine B is a fungal metabolite that has plant growth and circadian rhythm regulatory activity. Brevicompanine B inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various genes involved in the regulation of plant circadian rhythm. It is active against P. falciparum.
价 格：￥电议型 号：T71896产 地：中国大陆
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T71894AZD3229 Tosylate；化合物 AZD3229 TosylateAZD3229 Tosylate
AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal stromal tumors (GISTs).
价 格：￥电议型 号：T71894产 地：中国大陆
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T71893Clobetasol Propionate-d5；化合物 Clobetasol Propionate-d5Clobetasol Propionate-d5
Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a cell-free assay and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 ?g/ml. Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice. Formulations containing clobetasol propionate have been used in the t
价 格：￥电议型 号：T71893产 地：中国大陆
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T71891G-573；化合物 G-573G-573
G-573 is an allosteric inhibitor of MEK that is both potent and selective. The IC(50) value for pERK inhibition in HCT116 tumours by G-573 was estimated to be 0.406? ??M. The IC(50) values for tumour growth inhibition in HCT116 and H2122 were estimated to be 3.43 and 2.56???M, respectively. ED(50) estimates in HCT116 and H2122 mouse xenograft models were estimated to be ~4.6 and 1.9?mg/kg/day, respectively.
价 格：￥电议型 号：T71891产 地：中国大陆
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T71890F5446；化合物 F5446F5446
F5446 is a SUV39H1 inhibitor. F5446 has an EC50 of 0.496 μmol/L for SUV39H1 enzymatic activity. H3K9me3 was enriched in the promoters of GZMB, PRF1, FASLG, and IFNG in quiescent T cells. F5446 inhibited H3K9me3, thereby upregulating expression of these effectors in tumor-infiltrating CTLs and suppressing colon carcinoma growth in a CD8+ CTL-dependent manner in vivo. Our data indicate that SUV39H1 represses CTL effector gene expression and, in doing so, confers colon cancer immune escape.
价 格：￥电议型 号：T71890产 地：中国大陆
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T7189AMG9810化合物AMG9810(2E)-N-(2,3-二氢-1,4-苯并二噁英-6-基)-3-[4-(1,1-二甲基乙基)苯基]-2-丙酰胺
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively).
价 格：￥电议型 号：T7189产 地：中国大陆
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T7156NIBR189；化合物NIBR189NIBR189
NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)
价 格：￥电议型 号：T7156产 地：中国大陆
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T71242AZD-1897；化合物 AZD-1897AZD-1897
AZD-1897 is an ATP-competitive pan-PIM inhibitor. When combined with the Akt inhibitor AZD5363, AML cells from putative leukaemia stem cells incur a reduction in levels of the anti-apoptotic protein MCL1. The combination of PIM and Akt inhibition holds promise for the treatment of AML.
价 格：￥电议型 号：T71242产 地：中国大陆
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T71189RX 809055AX；化合物 RX 809055AXRX 809055AX
RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.
价 格：￥电议型 号：T71189产 地：中国大陆
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T70189Navoximod phosphate；化合物 Navoximod phosphateNavoximod phosphate
Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic.
价 格：￥电议型 号：T70189产 地：中国大陆
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T70187NPC-18915；化合物 NPC-18915NPC-18915
NPC-18915 is a benzofuran compound, inhibitor of neutophil activation.
价 格：￥电议型 号：T70187产 地：中国大陆
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T6S1894Linderane；乌药醚内酯Linderane
1. Linderane was characterized as a mechanism-based inactivator of CYP2C9.
价 格：￥电议型 号：T6S1894产 地：中国大陆
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T69189SANT-2；化合物 SANT-2SANT-2
SANT-2 is a potent inhibitor of Shh signaling pathway.
价 格：￥电议型 号：T69189产 地：中国大陆
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T6905Netupitant；奈妥吡坦Ro 67-31898/000|||CID 6451149；Ro 67-31898/000|||奈妥吡坦|||CID 6451149
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
价 格：￥电议型 号：T6905产 地：中国大陆
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T68778SIB-1893；化合物 SIB-1893SIB-1893
SIB-1893 is a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. It positive allosteric modulator at mGlu4 receptors.
价 格：￥电议型 号：T68778产 地：中国大陆
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T68356AM-3189；化合物 AM-3189AM-3189
AM-3189 is a potent and selective GPR40 Agonist with minimal CNS penetration, superior pharmacokinetic properties and in vivo efficacy comparable to AMG 837. AM-3189 maintains the in vivo efficacy of AMG 837 while displaying a superior pharmacokinetic profile and minimal CNS exposure. Similar to AMG 837, while highly potent on GPR40, AM-3189 was highly selective over the closely related GPCRs, GPR41 and GPR43. 13kdemonstrated low clearance, moderate volume of distribution, and good oral bioavai
价 格：￥电议型 号：T68356产 地：中国大陆
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T68223GSK-1018921 free base；化合物 GSK-1018921 free baseGSK-1018921 free base
GSK-1018921 free base is a selective GlyT1 inhibitor.
价 格：￥电议型 号：T68223产 地：中国大陆
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T68189Anpirtoline free base；化合物 Anpirtoline free baseAnpirtoline free base
Anpirtoline free base is a highly potent 5-HT1B receptor agonist. Anpirtoline has been shown to decreases central serotonin synthesis and attenuate aggressive behavior in vivo. Anpirtoline also acts as an antagonist at 5-HT3 receptors and can bypass the blood-brain barrier.
价 格：￥电议型 号：T68189产 地：中国大陆
