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T671892-(Fluoromethyl)-6-nitro-3-(o-tolyl)quinazolin-4(3H)-one;化合物 2-(Fluoromethyl)-6-nitro-3-(o-tolyl)qui
2-(Fluoromethyl)-6-nitro-3-(o-tolyl)quinazolin-4(3H)-one is a useful organic compound for research related to life sciences. The catalog number is T67189 and the CAS number is 56287-73-1.
价 格:¥电议型 号:T67189产 地:中国大陆
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T66189Boc-D-2-Nal-OH;化合物 Boc-D-2-Nal-OHBoc-D-2-Nal-OH
Boc-D-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66189 and the CAS number is 76985-10-9.
价 格:¥电议型 号:T66189产 地:中国大陆
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T6574Lumiracoxib;罗美昔布Prexige|||COX-189;Prexige|||罗美昔布|||COX-189
Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
价 格:¥电议型 号:T6574产 地:中国大陆
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T6543Indoximod吲哚莫德NLG-8189|||Indoximod (NLG-8189)|||1-Methyl-D-tryptophan|||吲哚莫德
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
价 格:¥电议型 号:T6543产 地:中国大陆
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T65189Fmoc-N-Me-D-Ala-OH;化合物 Fmoc-N-Me-D-Ala-OHFmoc-N-Me-D-Ala-OH
Fmoc-N-Me-D-Ala-OH is a useful organic compound for research related to life sciences and the catalog number is T65189.
价 格:¥电议型 号:T65189产 地:中国大陆
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T64189NNMT-IN-3;化合物 NNMT-IN-3NNMT-IN-3
NNMT-IN-3 (compound 14) is a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. nNMT-IN-3 can be used in studies of obesity, cancer, type II diabetes and skeletal sarcopenia, among other diseases.
价 格:¥电议型 号:T64189产 地:中国大陆
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T63897LDN193189 Tetrahydrochloride;化合物 LDN193189 TetrahydrochlorideLDN193189 Tetrahydrochloride
LDN193189 Tetrahydrochloride is a selective inhibitor of BMPI-type receptors and inhibits ALK2 (IC50: 5 nM) and ALK3 (IC50: 30 nM), with weak effects on ALK4, ALK5 and ALK7 (IC50 ≥ 500 nM).
价 格:¥电议型 号:T63897产 地:中国大陆
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T63189EGFR/BRAF-IN-1;化合物 EGFR/BRAF-IN-1EGFR/BRAF-IN-1
EGFR/BRAF-IN-1, a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent inhibitor of EGFR/BRAF, inhibiting BRAFV600E (IC50:45 nM) and cancer cell proliferation (GI50=35 nM), with good antioxidant effect.
价 格:¥电议型 号:T63189产 地:中国大陆
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T62340NBD-14189;化合物 NBD-14189NBD-14189
NBD-14189 is a potent HIV-1 entry antagonist, acting against HIV-1HXB2 pseudovirus (IC50: 89 nM).NBD-14189 binds HIV-1 gp120 and has a significant antiviral effect (EC50<200 nM).
价 格:¥电议型 号:T62340产 地:中国大陆
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T61899VEGFR2-IN-1;VEGFR2 抑制剂1VEGFR2-IN-1
VEGFR2-IN-1 is a selective and potent VEGFR2 inhibitor with antitumor activity that inhibits cell proliferation and migration and can be used in the study of breast cancer.
价 格:¥电议型 号:T61899产 地:中国大陆
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T61898RS6212;化合物 RS6212RS6212
RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M)。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.
价 格:¥电议型 号:T61898产 地:中国大陆
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T61897SMO-IN-1;化合物 SMO-IN-1SMO-IN-1
SMO-IN-1 (Compound 15) is an oral effective Smoothened (SMO) inhibitor. The EC50 value of sonic Hh protein (shh) is 89 nM.
价 格:¥电议型 号:T61897产 地:中国大陆
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T61896hCAIX-IN-12;化合物 hCAIX-IN-12hCAIX-IN-12
hCAIX-IN-12 is an effective hCAIX inhibitor, IC50 for CAIX and CAII is 0.74 and 10.78 μM , respectively. hCAIX-IN-12 inhibits cell proliferation and induces apoptosis. HCAIX-IN-12 can increase the generation of ROS. HCAIX-IN-12 has research potential in colorectal cancer (CRC).
价 格:¥电议型 号:T61896产 地:中国大陆
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T61895AZD7254;化合物 AZD7254AZD7254
AZD7254 is an oral effective Smoothened (SMO) inhibitor, and the EC50 of sonic Hh protein (shh) is 1.0 nM.
价 格:¥电议型 号:T61895产 地:中国大陆
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T61894sEH inhibitor-2;化合物 sEH inhibitor-2sEH inhibitor-2
SEH inhibitor-2 (compound 5l) is a soluble epoxide hydrolase (sEH) inhibitor with oral activity (IC50=0.9 nM), and the predicted oral absorption percentage is 71.2-88.4%. SEH inhibitor-2 can maintain a high concentration of eicosanoic acid (EETs) in serum. SEH inhibitor-2 has research value in cardiovascular protection.
价 格:¥电议型 号:T61894产 地:中国大陆
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T61893CSF1R-IN-12;化合物 CSF1R-IN-12CSF1R-IN-12
CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.
价 格:¥电议型 号:T61893产 地:中国大陆
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T61892CDK4/6-IN-8;化合物 CDK4/6-IN-8CDK4/6-IN-8
CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).
价 格:¥电议型 号:T61892产 地:中国大陆
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T61891SHP2-IN-8;化合物 SHP2-IN-8SHP2-IN-8
SHP2-IN-8 is a reversible, noncompetitive, selective and efficient allosteric SHP2 inhibitor (IC50=23 nM, Ki=22 nM), which also has effects in cells. SHP2-IN-8 can cause significant thermal displacement( Δ Tm = 7.01 ℃)。 SHP2-IN-8 can inhibit the phosphorylation of AKT and induce apoptosis of Hela cells.
价 格:¥电议型 号:T61891产 地:中国大陆
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T61890(E/Z)-BIO-acetoxime;化合物 (E/Z)-BIO-acetoxime(E/Z)-BIO-acetoxime
(E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。
价 格:¥电议型 号:T61890产 地:中国大陆
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T6189Mirdametinib;化合物PD0325901PD325901|||PD0325901;PD325901|||PD0325901
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis.
价 格:¥电议型 号:T6189产 地:中国大陆