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T8710MSAB;化合物MSABMSAB
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.
价 格:¥电议型 号:T8710产 地:中国大陆
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T8551Nitrobenzylthioinosine;S-(4-硝基苄基)-6-硫代肌苷NBMPR;NBMPR|||S-(4-硝基苄基)-6-硫代肌苷
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
价 格:¥电议型 号:T8551产 地:中国大陆
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T8542BMS-345541 hydrochloride化合物BMS-345541 hydrochlorideN-(1,8-二甲基咪唑并[1,2-A]喹喔啉-4-基)-1,2-乙二胺盐酸盐
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).
价 格:¥电议型 号:T8542产 地:中国大陆
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T8470BMS-1001;化合物BMS-1001BMS-1001
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
价 格:¥电议型 号:T8470产 地:中国大陆
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T84297BMS-986365;化合物 BMS-986365BMS-986365
BMS-986365 is a ligand-directed androgen receptor degrader (AR LDD) that inhibits androgen-stimulated transcription of AR target genes and can be used to study prostate cancer.
价 格:¥电议型 号:T84297产 地:中国大陆
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T839096-hydroxy Buspirone;化合物 6-hydroxy BuspironeBMY 28674|||BMS-52821;BMY 28674|||BMS-52821
6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, demonstrating efficacy in the rat hippocampus and dorsal raphe with half-maximal effective concentrations (EC50s) of 4 and 1 ?M, respectively. Furthermore, 6-Hydroxy Buspirone acts as a potent antagonist against dopamine D2, D3, and D4 receptors with half-maximal inhibitory conce
价 格:¥电议型 号:T83909产 地:中国大陆
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T8384Gatifloxacin hydrochloride;加替沙星盐酸盐AM-1155 (hydrochloride)|||BMS-206584 (hydrochloride)|||PD135432 (h
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.
价 格:¥电议型 号:T8384产 地:中国大陆
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T83706BMAP 28 (bovine) TFA;化合物 BMAP 28 (bovine) TFACathelicidin-5 (132-158)|||Bovine Myeloid Antimicrobial
Bovine Myeloid Antimicrobial Peptide (BMAP) 28, a synthetic peptide derived from bovine cathelicidin-5 (amino acids 132-158), exhibits antimicrobial activity against E. coli, S. aureus, MRSA, S. epidermidis, and the fungus C. albicans, with minimum inhibitory concentrations (MICs) of 2, 2, 4, 1, and 8 ?M respectively. At a concentration of 200 nM, BMAP 28 permeabilizes the inner membrane of E. coli, and at 5 ?M, it inhibits herpes simplex virus 1 (HSV-1) replication in Vero 76 cells. Furthermore
价 格:¥电议型 号:T83706产 地:中国大陆
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T83510[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2;化合物 [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2BM-PACAP;BM
[Arg-15,-20,-21, Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic analogue of PACAP 1-27 that exhibits a relaxant effect [1].
价 格:¥电议型 号:T83510产 地:中国大陆
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T8326BMS-2化合物BMS-21-(4-氟苯基)-N-[3-氟-4-(1H-吡咯并[2,3-B]吡啶-4-基氧基)苯基]-1,2-二氢-2-氧代-3-吡啶甲酰胺
BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.
价 格:¥电议型 号:T8326产 地:中国大陆
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T82994Anzurstobart;化合物 AnzurstobartBMS-986351|||CC-95251;BMS-986351|||CC-95251
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture assays with Rituximab and shows promise in solid and hematologic malignancy research [1].
价 格:¥电议型 号:T82994产 地:中国大陆
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T82853BM 15766 sulfate;化合物 BM 15766 sulfateBM 15766 sulfate
BM 15766 sulfate, an inhibitor of 7-dehydrocholesterol δ7-reductase, effectively reduces plasma cholesterol levels and functions as a hypolipidemic agent [1] [2].
价 格:¥电议型 号:T82853产 地:中国大陆
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T82852BMI-Glu;化合物 BMI-GluBMI-Glu
BMI-Glu, a selective γ-glutamyl transpeptidase (GGT) fluorescent probe, exhibits a Michaelis constant (Km) of 69.63 ?M and is characterized by its high sensitivity, good water solubility, and biocompatibility [1].
价 格:¥电议型 号:T82852产 地:中国大陆
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T82851BMP2-derived peptide;化合物 BMP2-derived peptideBMP2-derived peptide
BMP2-derived peptide, encompassing amino acids 73 to 92 of BMP-2, induces osteogenic differentiation in bone marrow stromal cells (BMSCs) and augments bone regeneration [1].
价 格:¥电议型 号:T82851产 地:中国大陆
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T82850BMS-332;化合物 BMS-332BMS-332
BMS-332 is a dual inhibitor of the lipid kinases DGKα and DGKζ, demonstrating half-maximal inhibitory concentrations (IC50) of 0.005 μM for DGKα and 0.001 μM for DGKζ [1].
价 格:¥电议型 号:T82850产 地:中国大陆
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T82849BMS-496;化合物 BMS-496BMS-496
BMS-496 is a dual DGKα/ζ lipid kinase inhibitor exhibiting IC50 values of 0.09 μM (DGKα) and 0.006 μM (DGKζ) [1].
价 格:¥电议型 号:T82849产 地:中国大陆
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T82848BMS-986172;化合物 BMS-986172BMS-986172
BMS-986172 is an orally active, highly selective inhibitor of MGAT2, demonstrating inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM for mouse MGAT2 (mMGAT2). It exhibits a half-life (T1/2) greater than 120 minutes in vitro and is known to decrease food intake and body weight. This compound is considered promising for the research of metabolic disorders, including obesity and non-alcoholic steatohepatitis (NASH) [1].
价 格:¥电议型 号:T82848产 地:中国大陆
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T82477Elosulfase alfa;化合物 Elosulfase alfaChondrosulfatase|||Chondrosulfatases|||BMN 110|||Chondroitinase||
Elosulfase alfa (BMN 110), a recombinant human N-acetylgalactosamine-6-sulfatase (GALNS), serves as enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), commonly referred to as Morquio A syndrome [1].
价 格:¥电议型 号:T82477产 地:中国大陆
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T82414Favezelimab;化合物 FavezelimabMK-4280;MK-4280
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that inhibits the LAG-3/MHC class II interaction and shows potential for use in colorectal cancer (CRC) research, particularly when combined with the PD-L1 inhibitor pembrolizumab [1] [2].
价 格:¥电议型 号:T82414产 地:中国大陆
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T82271Golocdacimab;化合物 GolocdacimabMEDI6570;MEDI6570
Golocdacimab (MEDI6570) is a fully human monoclonal antibody targeting LOX-1 with potential application in type 2 diabetes research [1].
价 格:¥电议型 号:T82271产 地:中国大陆