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  • T80252BMAP-18;化合物 BMAP-18BMAP-18

    BMAP-18 is a biologically active peptide, a truncated derivative of BMAP-27, which is part of the Cathelicidin family of peptides known for their potent bactericidal properties against pathogens such as Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. Unlike the full-length BMAP-27, which can be cytotoxic to human erythrocytes and neutrophils at concentrations higher than required for its antimicrobial effect, BMAP-18 offers increased cell selectivity due to its reduced hemolyt

    价 格:¥电议型 号:T80252产 地:中国大陆

  • T80215BMAP-28;化合物 BMAP-28BMAP-28

    BMAP-28, an antibiotic peptide, induces cell death by triggering the mitochondrial permeability transition pore and serves as a research tool in the study of microbial infections and cancer [1].

    价 格:¥电议型 号:T80215产 地:中国大陆

  • T80213BMAP-27;化合物 BMAP-27BMAP-27

    BMAP-27, an antimicrobial peptide, disrupts the membrane integrity of microorganisms, exhibiting inhibitory activity against bacteria and cancer cells due to its membrane permeability [1].

    价 格:¥电议型 号:T80213产 地:中国大陆

  • T80174BmP02;化合物 BmP02BmP02

    BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator. It delays Kv4.2 inactivation in HEK293T cells, exhibiting an EC50 of approximately 850 nM, and inhibits the transient outward potassium currents (Ito) in ventricular muscle cells [1] [2].

    价 格:¥电议型 号:T80174产 地:中国大陆

  • T80000Multiflorin B;化合物 Multiflorin BMultiflorin B

    Multiflorin B (compound 5), a kaempferol glycoside, can be extracted from the root of Neocheiropteris palmatopedata. This compound demonstrates the ability to inhibit nitric oxide production, achieving a 52% inhibition at a concentration of 20 μg/ml [1].

    价 格:¥电议型 号:T80000产 地:中国大陆

  • T79757Meliadubin B;化合物 Meliadubin BMeliadubin B

    Meliadubin B, a natural triterpenoid, effectively inhibits inflammatory responses by suppressing superoxide anion generation in human neutrophils (EC 50 of 5.54 μM) as well as inducible nitric oxide synthase activity. Additionally, it demonstrates significant antifungal properties against the rice pathogen Magnaporthe oryzae, with an IC 50 of 182.50 μM.

    价 格:¥电议型 号:T79757产 地:中国大陆

  • T79556NDBM;化合物 NDBMNDBM

    NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screening and killing. It possesses targeted action on lysosomes and a sensitive pH response, enabling the monitoring of intracellular pH variations associated with autophagy and external stimuli [1].

    价 格:¥电议型 号:T79556产 地:中国大陆

  • T79546BMP agonist 1;化合物 BMP agonist 1BMP agonist 1

    BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells. It acts by inhibiting GSK3β and enhancing β-catenin signaling, thereby synergistically modulating Id2 and Id3 expression. This compound is employed in skeletal disease and defect research [1].

    价 格:¥电议型 号:T79546产 地:中国大陆

  • T79223BMPR2-IN-1;化合物 BMPR2-IN-1BMPR2-IN-1

    BMPR2-IN-1 (Compound 8a), is a potent inhibitor of BMPR2, exhibiting an IC50 value of 506 nM and a Kd of 83.5 nM. It is utilized in the study of various diseases including pulmonary arterial hypertension, Alzheimer´s disease, and cancer [1].

    价 格:¥电议型 号:T79223产 地:中国大陆

  • T78659Crexavibart;化合物 CrexavibartBMS-986413|||C-144-LS;BMS-986413|||C-144-LS

    Crexavibart (BMS-986413; C-144-LS), an IgG1 λ2 antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].

    价 格:¥电议型 号:T78659产 地:中国大陆

  • T78294Tavolixizumab;化合物 TavolixizumabMEDI 0562|||Tavolimab;MEDI 0562|||Tavolimab

    Tavolixizumab (also known as MEDI 0562 and Tavolimab) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4), utilized in cancer immunology studies [1].

    价 格:¥电议型 号:T78294产 地:中国大陆

  • T78285Sofituzumab;化合物 SofituzumabMMUC 1206A;MMUC 1206A

    Sofituzumab (MMUC 1206A) is a humanized monoclonal antibody targeting the MUC16 antigen, specifically the recombinant V-kappa immunoglobulin variant [1].

    价 格:¥电议型 号:T78285产 地:中国大陆

  • T78249Nipocalimab;化合物 NipocalimabM281;M281

    Nipocalimab (M281), a fully human, recombinant, aglycosylated IgG1 monoclonal antibody, exhibits high-affinity binding to the Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6, characterized by its picomolar affinity and specificity as a human deglycosylated anti-FcRn monoclonal antibody [1] [2].

    价 格:¥电议型 号:T78249产 地:中国大陆

  • T78245Batoclimab;化合物 BatoclimabIMVT-1401|||HBM9161;IMVT-1401|||HBM9161

    Batoclimab, a human anti-FcRn monoclonal antibody, is utilized in the study of IgG-mediated autoimmune diseases [1].

    价 格:¥电议型 号:T78245产 地:中国大陆

  • T7804LGarenoxacin mesylate;化合物 T7804LGarenoxacin mesilate|||BMS 284756|||BM-284756|||BMS284756;Garenoxacin

    Garenoxacin mesylate, a novel oral des-fluoro quinolone, has potent antimicrobial activity against common respiratory pathogens, including resistant strains and Gram-negative and Gram-positive bacterial infections.

    价 格:¥电议型 号:T7804L产 地:中国大陆

  • T7804Garenoxacin mesylate hydrate;加雷沙星甲磺酸盐Garenoxacin mesylate [USAN]|||BMS284756 (Mesylate hydrate);Gare

    Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.

    价 格:¥电议型 号:T7804产 地:中国大陆

  • T7799BMP signaling agonist sb4;化合物SB 4SB 4;SB 4

    BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)

    价 格:¥电议型 号:T7799产 地:中国大陆

  • T77909Mirzotamab;化合物 MirzotamabMirzotamab

    Mirzotamab is an IgG1κ antibody targeting CD276/B7-H3 and is the naked antibody to Mirzotamab clezutoclax, consisting of 1320 amino acids.

    价 格:¥电议型 号:T77909产 地:中国大陆

  • T77874Maytansinoid B;化合物 Maytansinoid BMaytansinoid B

    Maytansinoid B, an ADC cytotoxin, conjugates with antibodies to create antibody-drug conjugates (ADCs). This antimitotic agent binds to tubulin, inhibiting microtubule assembly, and induces G2/M arrest in the cell cycle, leading to apoptosis [1] [2].

    价 格:¥电议型 号:T77874产 地:中国大陆

  • T7787BMS817378化合物BMS817378[3-[[4-((2-氨基-3-氯吡啶-4-基)氧基)-3-氟苯基]氨基甲酰基]-5-(4-氟苯基)-4-氧代-4H-吡啶-1-基]甲基磷酸二氢酯

    BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).

    价 格:¥电议型 号:T7787产 地:中国大陆

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