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  • T77772MiTMAB；化合物 MiTMABMiTMAB

    MiTMAB, a selective dynamin inhibitor, targets the interaction between dynamin and phospholipids. This inhibitor can inhibit dynamin GTPase activity with a Ki value of 940 nM.

    价 格：￥电议型 号：T77772产 地：中国大陆

  • T77761BMS-502；化合物 BMS-502BMS-502

    BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune responses in a dose-dependent manner and can be used to study immune-related diseases.

    价 格：￥电议型 号：T77761产 地：中国大陆

  • T77760BMS-684；化合物BMS-684BMS-684

    BMS-684 is a selective and potent DGKα inhibitor (IC50: 15 nM) with potential antitumor activity.BMS-684 inhibits DGKα kinase, DGKβ, and DGKγ.BMS-684 activates T-cells, which may prevent and treat immune-related diseases.

    价 格：￥电议型 号：T77760产 地：中国大陆

  • T77697BML-278；化合物BML-278BML278|||BML 278；BML278|||BML 278

    BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 induces cell cycle arrest in primary human mesenchymal stromal cells at the G1/S phase, and can be used to delay senescence.BML-278 reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts. BML-278 reduces microtubule protein

    价 格：￥电议型 号：T77697产 地：中国大陆

  • T77367Urelumab；乌瑞芦单抗BMS-663513|||BMS-66513；BMS-663513|||BMS-66513

    Urelumab(BMS-66513) is a humanized IgG4 monoclonal antibody, often used as a CD137 agonist.Urelumab has potential antitumor activity, potentiating tumor cell killing by T-cells and natural killer cells, and enhancing the cytotoxicity of Rituximab.Urelumab has been used in the study of solid tumor-related diseases such as diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). Urelumab can be used to study diseases associated with solid tumors such as diffuse large B-cell lymphoma (DL

    价 格：￥电议型 号：T77367产 地：中国大陆

  • T77333L(Iso)-BMT-124110 Formate；化合物 (Iso)-BMT-124110 Formate(R)-N-(8-((2-amino-2,4-dimethylpentyl)oxy)-5H-c

    (Iso)-BMT-124110 Formate has an inhibitory effect on the protein serine/threonine kinase AAK, and is used in the treatment of Parkinson´s disease, schizophrenia, neuropathic pain, and Alzheimer´s disease.

    价 格：￥电议型 号：T77333L产 地：中国大陆

  • T77132Clesrovimab；单抗ClesrovimabMK-1654；MK-1654

    Clesrovimab (MK1654) is an anti-respiratory syncytial virus protein F human monoclonal antibody for the prevention and treatment of respiratory syncytial virus infections.

    价 格：￥电议型 号：T77132产 地：中国大陆

  • T77090Mitazalimab；化合物 MitazalimabMitazalimab

    Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that exhibits directed activity against tumors. By activating antigen-presenting cells, such as dendritic cells (DC), it triggers the initiation of tumor-reactive T cells. Consequently, Mitazalimab promotes the infiltration and destruction of tumors by tumor-specific T cells and remodels the tumor-infiltrating myeloid microenvironment [1] [2].

    价 格：￥电议型 号：T77090产 地：中国大陆

  • T77088Mirikizumab；化合物 MirikizumabMirikizumab

    Mirikizumab (LY3074828), a humanized IgG4 monoclonal antibody, specifically targets the p19 subunit of interleukin 23. It is currently under research for its potential application in treating ulcerative colitis [1].

    价 格：￥电议型 号：T77088产 地：中国大陆

  • T77087Mipeginterferon alfa-2b；化合物 Mipeginterferon alfa-2bMipeginterferon alfa-2b

    Mipeginterferon alfa-2b, an analog of interferon alpha-2b (IFNA2B), features an average substitution of 5 among its 11 amino groups (one N-terminal and 10 lysine N6), and exhibits a relative molecular mass of 40 kDa [1].

    价 格：￥电议型 号：T77087产 地：中国大陆

  • T77085Mipasetamab；化合物 MipasetamabMipasetamab

    Mipasetamab, an IgG1κ antibody, targets AXL, a tyrosine kinase receptor and TAM Receptor. It plays a crucial role in synthesizing ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC), known for its anti-tumor activity [1].

    价 格：￥电议型 号：T77085产 地：中国大陆

  • T77084Mezagitamab；化合物 MezagitamabMezagitamab

    Mezagitamab (TAK-079), an IgG1λ anti-CD38 monoclonal antibody, functions by depleting tumor cells that express CD38 through both antibody and complement-dependent cytotoxicity. It shows potential for use in the treatment of relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) [1] [2] [3].

    价 格：￥电议型 号：T77084产 地：中国大陆

  • T77083Melrilimab；化合物 MelrilimabMelrilimab

    Melrilimab (GSK 3772847), an IgG2-kappa monoclonal antibody targeting IL1RL1/ST2/IL33R/DER4/FIT-1, is utilized in asthma research [1].

    价 格：￥电议型 号：T77083产 地：中国大陆

  • T77081Mazorelvimab；化合物 MazorelvimabMazorelvimab

    Mazorelvimab (SYN023), a cocktail composed of the humanized monoclonal antibodies CTB011 and CTB012, targets the rabies virus (RABV) by binding to non-overlapping epitopes on the RABV´s glycoprotein (G). This interaction showcases Mazorelvimab´s potential in rabies prevention [1] [2].

    价 格：￥电议型 号：T77081产 地：中国大陆

  • T77080Manfidokimab；化合物 ManfidokimabManfidokimab

    Manfidokimab (AK120), an IgG4 monoclonal antibody targeting the interleukin 4 receptor alpha (IL-4Rα), demonstrates therapeutic efficacy as detailed in reference [1].

    价 格：￥电议型 号：T77080产 地：中国大陆

  • T77079Manelimab；化合物 ManelimabManelimab

    Manelimab is a monoclonal antibody that inhibits programmed death-ligand 1 ( PD-L1 ) [1] .

    价 格：￥电议型 号：T77079产 地：中国大陆

  • T77078Maftivimab；化合物 MaftivimabMaftivimab

    Maftivimab (REGN3470-3471-3479), also known as Atoltivimab, Odesivimab (Inmazeb), is a Filovirus inhibitor and a Food and Drug Administration (FDA)-approved agent for the research of Zaire ebolavirus infection [1].

    价 格：￥电议型 号：T77078产 地：中国大陆

  • T76830Teneliximab；化合物TeneliximabChi220|||Anti-Human CD40 Recombinant Antibody|||BMS 224819；Chi220|||Anti-H

    Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD40 and peripheral B-cell depletion, and may be used to study organ transplant rejection and rheumatoid arthritis.

    价 格：￥电议型 号：T76830产 地：中国大陆

  • T76819Metelimumab；化合物 MetelimumabMetelimumab

    Metelimumab (CAT-192), a human IgG4 monoclonal antibody, selectively neutralizes TGFβ1 [1].

    价 格：￥电议型 号：T76819产 地：中国大陆

  • T76794Ulocuplumab；乌洛鲁单抗BMS 936564|||MDX 1338；BMS 936564|||MDX 1338

    Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin´s lymphoma (NHL), and multiple myeloma transplantation models.Ulocplumab inhibits the migration of chronic lymphocytic leukemia (CLL) cells under CXCR4 activation, induces apoptosis, and inhibits the growth and migration of cancer cells. Ulocplumab inhibits CXCL12-mediated chronic lymphocytic leukemia (CLL) cell migration in response to CXCR

    价 格：￥电议型 号：T76794产 地：中国大陆

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