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T69163BML277 Acid;化合物 BML277 AcidBML277 Acid
BML277 Acid is a metabolite of BML277 which is a selective checkpoint kinase 2 inhibitor.
价 格:¥电议型 号:T69163产 地:中国大陆
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T68935BMS-645737;化合物 BMS-645737BMS-645737
BMS-645737 is an inhibitor of vascular endothelial growth factor (VEGF) receptor-2 and fibroblast growth factor (FGF) receptor-1. BMS-646737 has anti-angiogenic activity and was evaluated in nonclinical studies as a treatment for cancer.
价 格:¥电议型 号:T68935产 地:中国大陆
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T6864Ixabepilone;伊沙匹隆BMS 247550|||Ixempra|||Azaepothilone B|||BMS 247550-1;BMS 247550|||Ixempra|||Azaepot
Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.
价 格:¥电议型 号:T6864产 地:中国大陆
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T68558BML-288;化合物 BML-288BML-288
BML-288 is a phosphodiesterase Type II (PDE2) inhibitor that demonstrates no inhibition of 5-lipoxygenase (5-LO) or cyclooxygenase (COX-1).
价 格:¥电议型 号:T68558产 地:中国大陆
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T68447BM-42304;化合物 BM-42304BM-42304
BM-42304 is an inhibitor of fatty acid oxidation.
价 格:¥电议型 号:T68447产 地:中国大陆
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T68410CBM 301940;化合物 CBM 301940CBM 301940
CBM 301940 is a potent malonyl-CoA decarboxylase inhibitor that is orally bioavailable.
价 格:¥电议型 号:T68410产 地:中国大陆
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T68266BMS-751324;化合物 BMS-751324BMS-751324
BMS-751324, a p38α MAPK inhibitor, features a carbamyl-methyl linkage precursor with esters and phosphate functional groups from hydroxyphenylacetic acid (HPA). It effectively reduces foot swelling and suppresses LPS-induced TNFα production in an arthritic rat model.
价 格:¥电议型 号:T68266产 地:中国大陆
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T68227BMS-214662 HCl;化合物 BMS-214662 HClBMS-214662 HCl
BMS-214662 is a Farnesyltransferase inhibitor , is also a nonsedating benzodiazepine derivative with potential antineoplastic activity. BMS-214662 inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction, which may result in the inhibition of Ras function and apoptosis in susceptible tumor cells. This agent may reverse the malignant phenotype of H-Ras-transformed cells and has been shown to be active against tumor cell
价 格:¥电议型 号:T68227产 地:中国大陆
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T68170Xl-281;化合物 Xl-281BMS-908662;BMS-908662
Xl-281 (BMS-908662) is a BRAF inhibitor with anti-tumor activity for the study of colorectal cancer and melanoma.
价 格:¥电议型 号:T68170产 地:中国大陆
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T68043Ciamexon;腈美克松Ciamexone|||BM 41332|||BM41332|||BM-41332;Ciamexone|||BM 41332|||BM41332|||BM-41332
Ciamexon (Ciamexone) is a novel immunomodulator that has shown promising results in experimental models of autoimmune disease with little demonstrated cytotoxicity.Ciamexon can be used to study endocrine ophthalmopathies and diabetes mellitus, with slight improvement in ophthalmic disease following short-term administration.
价 格:¥电议型 号:T68043产 地:中国大陆
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T68022LSulotroban potassium;磺曲苯钾盐BM 13177 potassium|||Sulotroban potassium(72131-33-0 Free base);BM 13177 p
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.
价 格:¥电议型 号:T68022L产 地:中国大陆
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T6789BMS582949;化合物BMS582949BMS 582949|||PS540446|||BMS-582949;BMS 582949|||PS540446|||BMS-582949
BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13 nM, inhibiting both p38 kinase activity and activation of p38.
价 格:¥电议型 号:T6789产 地:中国大陆
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T67818BMS-641988;化合物BMS-641988BMS-641988
BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.
价 格:¥电议型 号:T67818产 地:中国大陆
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T67791BMS-903452;化合物BMS-903452BMS-903452
BMS-903452 is a potent and selective GPR119 agonist with EC50 of 14 nM. BMS-903452 is indicated for the treatment of acute and chronic rodent diabetes. GPR119 was mainly expressed in pancreatic b cells and gastrointestinal endocrine cells. GPR119 had no significant inhibitory effect on 9 different cytochrome P450 enzymes (IC50 > 40 μM), did not activate PXR (EC50>50 μM), and was not toxic to liver (HEPG2) cell lines.
价 格:¥电议型 号:T67791产 地:中国大陆
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T67739BMY-14802;化合物BMY-14802alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol;alpha-(
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
价 格:¥电议型 号:T67739产 地:中国大陆
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T67703mTOR inhibitor 9b;化合物 mTOR inhibitor 9bmTOR inhibitor 9b
mTOR inhibitor 9b is an enzyme inhibitor of protein kinase mTOR he phosphatidylinositol 3-kinase PIK3CA with IC50s of 0.76 nm and 1.262 ?M, respectively.mTOR inhibitor 9b possesses anticancer activity and can be used to study leukemia, skin, breast, lung and colon cancers.
价 格:¥电议型 号:T67703产 地:中国大陆
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T6735XL413 hydrochloride;化合物XL413 hydrochlorideBMS-863233 Hydrochloride|||XL413|||BMS-863233;BMS-863233 H
XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC 50 of 3.4 nM. XL413 hydrochloride also exhibits potent effect with IC 50 s of 215, 42 nM on CK2, PIM1, respectively, and an EC 50 of 118 nM on pMCM.
价 格:¥电议型 号:T6735产 地:中国大陆
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T67265Ru(Oac)2[(S)-Dtbm-Segphos];化合物 Diacetato{(S)-(+)-5,5’-bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphin
Ru(Oac)2[(S)-Dtbm-Segphos] has a wide range of applications in life science related research.
价 格:¥电议型 号:T67265产 地:中国大陆
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T6529Halobetasol propionate;卤倍他索丙酸酯Halobetasol Propionate|||Ulobetasol propionate|||BMY-30056|||CGP-1445
Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phos
价 格:¥电议型 号:T6529产 地:中国大陆
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T6420BMS-707035化合物BMS707035N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:中国大陆