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  • T39789BMS-986235；化合物BMS-986235BMS-986235|||LAR-1219；BMS-986235|||LAR-1219

    BMS-986235 (LAR-1219) is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 can be used in studies about the prevention of heart failure.

    价 格：￥电议型 号：T39789产 地：中国大陆

  • T39779BMT-297376；BMT-297376BMT-297376

    BMT-297376, the optimized Linrodostat, is a potent IDO1 inhibitor.

    价 格：￥电议型 号：T39779产 地：中国大陆

  • T39654Afimetoran；化合物AfimetoranBMS-986256；BMS-986256

    Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.

    价 格：￥电议型 号：T39654产 地：中国大陆

  • T39647BMS-986278；化合物BMS-986278BMS-986278

    BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively.BMS-986278 may be investigated for use in idiopathic pulmonary fibrosis.

    价 格：￥电议型 号：T39647产 地：中国大陆

  • T39448BMS-986224；化合物BMS-986224BMS 986224；BMS 986224

    BMS-986224 is an orally active, potent, and selective APJ receptor agonist. BMS-986224 has the potential to study heart failure.

    价 格：￥电议型 号：T39448产 地：中国大陆

  • T39399ABM-14；ABM-14ABM-14

    ABM-14, a ligand for the androgen receptor (AR), is utilized as a targeting agent in PROTAC. By binding to a ligand for the von Hippel-Lindau protein (VHL) via a linker, ABM-14 forms ARCC-4, which facilitates the degradation of AR.

    价 格：￥电议型 号：T39399产 地：中国大陆

  • T39245Poricoic acid BM；Poricoic acid BMPoricoic acid BM

    Poricoic acid BM is a lanostane triterpenoid present in the peels of Wolfiporia cocos mushrooms.

    价 格：￥电议型 号：T39245产 地：中国大陆

  • T39238DBM-MMAF；DBM-MMAFDBM-MMAF

    DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).

    价 格：￥电议型 号：T39238产 地：中国大陆

  • T39223MilvexianMilvexianJNJ-70033093|||BMS-986177

    Milvexian (BMS-986177) is a potent antithrombotic compound that inhibits human and rabbit factor XIa (FXIa) directly and reversibly. It is orally-bioavailable and exhibits a K i of 0.11 nM and 0.38 nM against human and rabbit FXIa, respectively.

    价 格：￥电议型 号：T39223产 地：中国大陆

  • T39129BMS-986143；BMS-986143BMS-986143

    BMS-986143, an orally active, reversible BTK inhibitor with an IC50 value of 0.26 nM, is designed for autoimmune disease research. Additionally, it targets TEC, BLK, BMX, TXK, FGR, YES1, and ITK, exhibiting IC50s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM, 19 nM, and 21 nM, respectively [1].

    价 格：￥电议型 号：T39129产 地：中国大陆

  • T39106BMSpep-57；BMSpep-57BMSpep-57

    BMSpep-57, a potent macrocyclic peptide inhibitor, competitively disrupts the PD-1/PD-L1 interaction, demonstrating a significant inhibitory concentration (IC50) of 7.68 nM. It exhibits binding affinity towards PD-L1 with dissociation constants (Kd) of 19 nM and 19.88 nM in MicroScale Thermophoresis (MST) and Surface Plasmon Resonance (SPR) assays, respectively. This compound enhances T cell functionality by promoting Interleukin-2 (IL-2) production within Peripheral Blood Mononuclear Cells (PBM

    价 格：￥电议型 号：T39106产 地：中国大陆

  • T38959BMS-604992 dihydrochlorideBMS-604992 dihydrochlorideEX-1314 dihydrochloride|||BMS-604992 dihydrochlo

    BMS-604992 (EX-1314) dihydrochloride is a selective and orally active small-molecule agonist of the growth hormone secretagogue receptor (GHSR). It exhibits high-affinity binding (k i = 2.3 nM) and potent functional activity (EC 50 = 0.4 nM). Furthermore, BMS-604992 dihydrochloride has been shown to stimulate food intake in rodents.

    价 格：￥电议型 号：T38959产 地：中国大陆

  • T38922BMS-963272；化合物 BMS-963272BMS-963272

    BMS-963272 is a selective and potent MGAT2 inhibitor with an IC50 value of 7.1 nM used in the study of metabolic disorders and obesity.

    价 格：￥电议型 号：T38922产 地：中国大陆

  • T38837Microcolin B；Microcolin BMicrocolin B

    Microcolin B, an acylpeptide immunosuppressant, is a highly potent and biologically unique compound containing proline. It is derived from the blue-green alga Lyngbya majuscule.

    价 格：￥电议型 号：T38837产 地：中国大陆

  • T38810BM-1197；BM-1197BM-1197

    BM-1197, a highly potent and specific dual inhibitor of Bcl-2 and Bcl-xL, effectively targets these proteins with IC50 values of 3.5 nM and 5.2 nM for Bcl-2 and Bcl-xL, respectively. This compound demonstrates notable antitumor activity in both in vitro and in vivo settings.

    价 格：￥电议型 号：T38810产 地：中国大陆

  • T38789BMS-984923；BMS-984923BMS-984923

    BMS-984923, a highly potent silent allosteric modulator (SAM) of mGluR5, demonstrates exceptional binding affinity (K i = 0.6 nM). Additionally, this compound possesses favorable oral bioavailability and blood-brain barrier (BBB) penetration. BMS-984923 effectively inhibits the interaction between PrPC and mGluR5, preventing pathological Aβo signaling, while leaving physiological glutamate signaling unaffected.

    价 格：￥电议型 号：T38789产 地：中国大陆

  • T38609Mycalolide B；Mycalolide BMycalolide B

    Mycalolide-B is a marine sponge-derived compound that functions as a selective inhibitor of actomyosin ATPase. It effectively hinders ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+.

    价 格：￥电议型 号：T38609产 地：中国大陆

  • T38607Etoposide phosphate disodiumEtoposide phosphate disodiumBMY-40481 disodium|||Etoposide phosphate dis

    Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, functions as a potent chemotherapeutic agent by selectively inhibiting topoisomerase II, hindering the re-ligation of DNA strands. It is regarded as the active equivalent of etoposide, effectively inducing cell cycle arrest, apoptosis, and autophagy in cancer cells.

    价 格：￥电议型 号：T38607产 地：中国大陆

  • T38397BMS-753426；BMS-753426BMS-753426

    BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .

    价 格：￥电议型 号：T38397产 地：中国大陆

  • T37889BHBM；BHBMBHBM

    BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1

    价 格：￥电议型 号：T37889产 地：中国大陆

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